{"disease":{"id":"cognitive-dysfunction-postoperative","name":"cognitive dysfunction postoperative"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06268249","title":"Ulinastatin Improves Post-Cardiac Surgery Cognitive Dysfunction","phase":"","overall_status":"COMPLETED","enrollment_count":7065,"lead_sponsor_name":"Qin Zhang","has_results":false},{"nct_id":"NCT04965324","title":"Depth of Anaesthesia and Long-term Survival: The Balanced Anaesthesia Follow-up Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":6644,"lead_sponsor_name":"Auckland City Hospital","has_results":false},{"nct_id":"NCT05439707","title":"Effects of Perioperative Transauricular Vagus Nerve Electrical Stimulation on POD, POCD and CPSP","phase":"NA","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"Xuzhou Central Hospital","has_results":false},{"nct_id":"NCT04787536","title":"Perioperative Cognitive Trajectories in Deferred Surgery (CoTELE-SURGE)","phase":"","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"McMaster University","has_results":false},{"nct_id":"NCT07192549","title":"Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pediatric Surgery","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"General Hospital of Ningxia Medical University","has_results":false},{"nct_id":"NCT03074604","title":"Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce Neurological Injuries After Surgical Coronary Revascularization (CANON): a Randomised, Controlled, Investigator and Patient Blinded Single Center Superiority Trial With Three Parallel Arms.","phase":"NA","overall_status":"COMPLETED","enrollment_count":192,"lead_sponsor_name":"Collegium Medicum w Bydgoszczy","has_results":false},{"nct_id":"NCT06704451","title":"Perioperative IL-33 is Associated with the Early Stage of Postoperative Neurocognitive Dysfunction After Major Abdominal Surgery","phase":"","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"First Affiliated Hospital of Kunming Medical University","has_results":false},{"nct_id":"NCT07509372","title":"Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium","phase":"","overall_status":"COMPLETED","enrollment_count":137,"lead_sponsor_name":"Ankara University","has_results":false},{"nct_id":"NCT06752421","title":"Effect of Low Tidal Volume Ventilation on Postoperative Delirium","phase":"NA","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"Nevsehir Public Hospital","has_results":false},{"nct_id":"NCT07113483","title":"Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"Romanian Society for Enteral and Parenteral Nutrition","has_results":false},{"nct_id":"NCT06371638","title":"Dexmedetomidine and Postoperative Cognitive Dysfunction (POCD)","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":112,"lead_sponsor_name":"Udayana University","has_results":false},{"nct_id":"NCT04214496","title":"Electroencephalographic Biomarker to Predict Acute Post-operatory Cognitive Dysfunction","phase":"","overall_status":"COMPLETED","enrollment_count":106,"lead_sponsor_name":"University of Chile","has_results":false},{"nct_id":"NCT07000461","title":"Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass","phase":"","overall_status":"RECRUITING","enrollment_count":106,"lead_sponsor_name":"Bakirkoy Dr. Sadi Konuk Research and Training Hospital","has_results":false},{"nct_id":"NCT03966950","title":"Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia","phase":"NA","overall_status":"UNKNOWN","enrollment_count":104,"lead_sponsor_name":"University of Sao Paulo","has_results":false},{"nct_id":"NCT07361068","title":"Assessment of Brain Oxygen Drops During Surgery and Related Risk Factors for Cognitive Problems After Heart Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Bursa Yuksek Ihtisas Training and Research Hospital","has_results":false},{"nct_id":"NCT05364216","title":"Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":92,"lead_sponsor_name":"The First Hospital of Qinhuangdao","has_results":false},{"nct_id":"NCT06597812","title":"the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium","phase":"","overall_status":"COMPLETED","enrollment_count":84,"lead_sponsor_name":"Amasya University","has_results":false},{"nct_id":"NCT04634656","title":"Lidocaine on Early Cognitive Dysfunction in Shoulder Arthroscopy","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT06689137","title":"Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":80,"lead_sponsor_name":"Haseki Training and Research Hospital","has_results":false},{"nct_id":"NCT04191642","title":"Correlation of NLRP3 With Cognitive Dysfunction Early After Heart Valve Replacement Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"General Hospital of Ningxia Medical University","has_results":false},{"nct_id":"NCT04195204","title":"A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surgery","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":72,"lead_sponsor_name":"Beijing Chao Yang Hospital","has_results":false},{"nct_id":"NCT06797713","title":"Effect of Targeted Fluid Therapy on Postoperative Cognitive Dysfunction.","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT05209555","title":"Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)","phase":"","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Catharina Ziekenhuis Eindhoven","has_results":false},{"nct_id":"NCT06005363","title":"CSF Metabolomics and Glymphatic Function in Patients Receiving VP- Shunt Surgery.","phase":"NA","overall_status":"RECRUITING","enrollment_count":48,"lead_sponsor_name":"Chang Gung Memorial Hospital","has_results":false},{"nct_id":"NCT04837391","title":"Postoperative Cognitive Dysfunction in Elderly Urologic Oncology Patients (POCD)","phase":"","overall_status":"UNKNOWN","enrollment_count":48,"lead_sponsor_name":"Istanbul University","has_results":false},{"nct_id":"NCT06925711","title":"The Effect of Hypotensive Anesthesia on Cognitive Functions in Orthognatic Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"Medipol University","has_results":false},{"nct_id":"NCT03683537","title":"Association Between Changes of GFAP After Surgery and Postoperative Delayed Cognitive Recovery","phase":"","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Moscow Clinical Scientific Center","has_results":false},{"nct_id":"NCT07339124","title":"The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":30,"lead_sponsor_name":"Ankara Ataturk Sanatorium Training and Research Hospital","has_results":false},{"nct_id":"NCT03337282","title":"Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients","phase":"","overall_status":"TERMINATED","enrollment_count":23,"lead_sponsor_name":"Ciusss de L'Est de l'Île de Montréal","has_results":false},{"nct_id":"NCT04246320","title":"Taking Brain Monitoring to the Next Level","phase":"NA","overall_status":"COMPLETED","enrollment_count":7,"lead_sponsor_name":"University of California, Los Angeles","has_results":false},{"nct_id":"NCT05398757","title":"Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Osijek University Hospital","has_results":false}],"total":31},"guidelines":[],"source":"Drug Landscape verified database"}