{"disease":{"id":"chronic-periodontitis","name":"chronic periodontitis"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03369405","title":"Thyroid Disease and Chronic Periodontitis","phase":"","overall_status":"COMPLETED","enrollment_count":4965,"lead_sponsor_name":"University at Buffalo","has_results":false},{"nct_id":"NCT04277390","title":"microRNA 155 Levels and Periodontal Microflora (Bacteria and Virus) in Preeclampsia.","phase":"","overall_status":"COMPLETED","enrollment_count":445,"lead_sponsor_name":"Meenakshi Ammal Dental College and Hospital","has_results":false},{"nct_id":"NCT07069881","title":"Sonic vs Passive Ultrasonic Irrigation for Chronic Apical Periodontitis","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Nanfang Hospital, Southern Medical University","has_results":false},{"nct_id":"NCT02585596","title":"A Phase II Clinical Trial of YH23537 in Patients With Chronic Periodontal Disease.","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":275,"lead_sponsor_name":"Yuhan Corporation","has_results":false},{"nct_id":"NCT03610607","title":"Intense Education of Periodontal Health Maintenance","phase":"NA","overall_status":"COMPLETED","enrollment_count":270,"lead_sponsor_name":"Meharry Medical College","has_results":false},{"nct_id":"NCT04026828","title":"Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Kocaeli University","has_results":false},{"nct_id":"NCT04047212","title":"The Link Between Periodontitis, Smoking and Oral Cancer","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT03364751","title":"Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome","phase":"NA","overall_status":"COMPLETED","enrollment_count":179,"lead_sponsor_name":"Philip Morris Products S.A.","has_results":true},{"nct_id":"NCT06833515","title":"The Effect of Using Reciprocal Files Alone and With Different Files on Postoperative Pain","phase":"NA","overall_status":"COMPLETED","enrollment_count":168,"lead_sponsor_name":"Harran University","has_results":false},{"nct_id":"NCT06578832","title":"Assessment of The Oral Health Status of Children With Chronic Kidney Disease","phase":"","overall_status":"COMPLETED","enrollment_count":167,"lead_sponsor_name":"Marmara University","has_results":false},{"nct_id":"NCT07388901","title":"In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers","phase":"NA","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"The Dental Hospital of Zhejiang University School of Medicine","has_results":false},{"nct_id":"NCT03343366","title":"Glycemic Control in T2DM Through Non-Surgical Periodontal Therapy","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Dow University of Health Sciences","has_results":false},{"nct_id":"NCT06481059","title":"suPAR is a Potential Biomarker of in Chronic Periodontitis Through the Impact of Post-radiotherapy on HNCs Patients","phase":"","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Al-Maarif University College","has_results":false},{"nct_id":"NCT06529588","title":"Estimation of (suPAR) in Chronic Periodontitis With Post-radiotherapy on HNCs Patients","phase":"","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Al-Maarif University College","has_results":false},{"nct_id":"NCT07033247","title":"The Effect of Different Sodium Hypochlorite Concentrations and Activation Techniques on Postoperative Pain","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Cukurova University","has_results":false},{"nct_id":"NCT03745300","title":"Comparative Evaluation Of 1.2% Atorvastatin and 1.2% Simvastatin Gel Local Drug Delivery And Redelivery In Chronic Periodontitis Subjects With Diabetes Mellitus: A Randomized Controlled Clinical Trial.","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Government Dental College and Research Institute, Bangalore","has_results":false},{"nct_id":"NCT04070729","title":"Injectable Platelet Rich Fibrin With Non Surgical Periodontal Therapy","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Institute of Dental Sciences, Bareilly, Uttar Pradesh, India","has_results":false},{"nct_id":"NCT06856369","title":"Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":120,"lead_sponsor_name":"Bahria University","has_results":false},{"nct_id":"NCT04503746","title":"A Study to Evaluate the Efficacy and Safety of ALH-L1005 in Patients With Chronic Periodontitis","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":117,"lead_sponsor_name":"AngioLab, Inc.","has_results":false},{"nct_id":"NCT05231096","title":"Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic Periodontitis","phase":"NA","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"Dow University of Health Sciences","has_results":false},{"nct_id":"NCT07262606","title":"Salivary Mitofusin-1 Levels in Periodontitis: Associations With Disease Severity, Smoking, and Treatment Response","phase":"NA","overall_status":"RECRUITING","enrollment_count":104,"lead_sponsor_name":"Ömer Faruk Okumuş","has_results":false},{"nct_id":"NCT07427069","title":"Chronic Kidney Disease Associated Diet","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":100,"lead_sponsor_name":"Recep Tayyip Erdogan University Training and Research Hospital","has_results":false},{"nct_id":"NCT02672384","title":"Chronic Periodontitis in Critically Ill Patients: Diagnosis and Epidemiology","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"University Hospital, Brest","has_results":false},{"nct_id":"NCT03553095","title":"Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":92,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT07057336","title":"Evaluation of Post-Operative Pain Following the Use of Nano-Calcium Hydroxide","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Cukurova University","has_results":false},{"nct_id":"NCT05498012","title":"CBD Effects on Periodontal Health of Patients With Chronic Periodontitis","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Palacky University","has_results":false},{"nct_id":"NCT03354338","title":"Amoxicillin to Prevent Bacteria and Inflammatory Biomarkers After Intensive Periodontal Therapy","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":90,"lead_sponsor_name":"Universidad El Bosque, Bogotá","has_results":false},{"nct_id":"NCT03204058","title":"Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Government Dental College and Research Institute, Bangalore","has_results":false},{"nct_id":"NCT03225950","title":"Interaction Between Immune Cells and Bacteria Associated With Periodontitis","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"University of Copenhagen","has_results":false},{"nct_id":"NCT04262011","title":"Effect of Non-surgical Periodontal Treatment and C-reactive Protein Levels in Hemodialysis Patients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":88,"lead_sponsor_name":"Universidade Federal de Santa Maria","has_results":false},{"nct_id":"NCT07353606","title":"Cofilin-2 (rs80358250) and Lactoferrin (rs1126478) Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CHD","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":84,"lead_sponsor_name":"Meenakshi Ammal Dental College and Hospital","has_results":false},{"nct_id":"NCT03308019","title":"Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers.","phase":"NA","overall_status":"COMPLETED","enrollment_count":83,"lead_sponsor_name":"King Saud University","has_results":false},{"nct_id":"NCT06895980","title":"Effect of Periodontal Treatment on Metabolic Control in Patients with Type-2 Diabetes Mellitus Treated in the Cardiovascular Healt Program","phase":"NA","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"University of Chile","has_results":false},{"nct_id":"NCT06860191","title":"Effect of Different Sealers and Activation Methods on Pain","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":80,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT03621891","title":"Alterations in Subgingival Microbiota and Hypoxia in Occlusal Trauma","phase":"","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Tokat Gaziosmanpasa University","has_results":false},{"nct_id":"NCT04857346","title":"Antimicrobial Photodynamic Therapy in Chronic Periodontitis and Diabetes Mellitus","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"King Saud University","has_results":false},{"nct_id":"NCT06834711","title":"Chlorhexidine Versus N-Asetil Sistein Irrigation in Mandibular Molar Teeth with Chronic Apical Periodontitis","phase":"NA","overall_status":"COMPLETED","enrollment_count":78,"lead_sponsor_name":"Cukurova University","has_results":false},{"nct_id":"NCT04583085","title":"Interplay of miRNA-146a and miRNA-126 in Chronic Periodontitis Patients With Coronary Artery Disease","phase":"","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Meenakshi Ammal Dental College and Hospital","has_results":false},{"nct_id":"NCT04074915","title":"Effects of Herbal Mouth Rinse for Chronic Periodontitis","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Institute of Dental Sciences, Bareilly, Uttar Pradesh, India","has_results":false},{"nct_id":"NCT05852366","title":"Efficacy of Herbal Dentifrice for Management of Dentinal Hypersensitivity","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Dr. D. Y. Patil Dental College & Hospital","has_results":false},{"nct_id":"NCT06043687","title":"Efficacy of Herbal Dentifrice in Treatment of Chronic Periodontitis","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Dr. D. Y. Patil Dental College & Hospital","has_results":false},{"nct_id":"NCT03041480","title":"Serum Lipid Levels and Lp-PLA2 in Chronic Periodontitis","phase":"","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Meenakshi Ammal Dental College and Hospital","has_results":false},{"nct_id":"NCT03241511","title":"Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"UConn Health","has_results":false},{"nct_id":"NCT03741374","title":"Minimally-invasive Non-surgical Therapy of Intrabony Defects","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":66,"lead_sponsor_name":"Queen Mary University of London","has_results":false},{"nct_id":"NCT03749369","title":"Adjunctive Use of Salvadora Persica in Chronic Periodontitis","phase":"EARLY_PHASE1","overall_status":"UNKNOWN","enrollment_count":66,"lead_sponsor_name":"King Saud University","has_results":false},{"nct_id":"NCT05663476","title":"NSPT On Vitronectin And Fetuin-A Levels In Patients With Periodontitis And Coronary Artery Disease","phase":"NA","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Meenakshi Ammal Dental College and Hospital","has_results":false},{"nct_id":"NCT05995158","title":"Metagenomic Analysis of the Link Between Periodontitis and Smoking: Case-control Study","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"King Abdulaziz University","has_results":false},{"nct_id":"NCT05744661","title":"Mechanical Vs Chemomechanical Method For Calcium Hydroxide Removal","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Pakistan Institute of Medical Sciences","has_results":false},{"nct_id":"NCT03644901","title":"Assessment of Response to the Conventional Periodontal Treatment Based on the Blood Group Phenotypes.","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Damascus University","has_results":false},{"nct_id":"NCT01647282","title":"Local Minocycline to Reduce Future Inflammation and Bone Loss in Periodontal Maintenance Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"University of Nebraska","has_results":true}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}