{"disease":{"id":"central-nervous-system-neoplasms","name":"central nervous system neoplasms"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT00276640","title":"Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas","phase":"NA","overall_status":"COMPLETED","enrollment_count":3417,"lead_sponsor_name":"Societe Internationale d'Oncologie Pediatrique","has_results":false},{"nct_id":"NCT03147989","title":"Retrospective Study of MRI With MULTIHANCE at 0.10 and 0.05 mmol/Kg Dose in CNS Patients","phase":"","overall_status":"COMPLETED","enrollment_count":352,"lead_sponsor_name":"Bracco Diagnostics, Inc","has_results":false},{"nct_id":"NCT03012620","title":"Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":334,"lead_sponsor_name":"UNICANCER","has_results":false},{"nct_id":"NCT03750188","title":"Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs","phase":"","overall_status":"COMPLETED","enrollment_count":125,"lead_sponsor_name":"Bracco Diagnostics, Inc","has_results":false},{"nct_id":"NCT04446962","title":"LOC-R01 Study of Lenalidomide and Ibrutinib in Association With Rituximab-Methotrexate Procarbazine Vincristin (R-MPV)","phase":"PHASE1, PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":118,"lead_sponsor_name":"Institut Curie","has_results":false},{"nct_id":"NCT05850377","title":"5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":90,"lead_sponsor_name":"Sociedad de Lucha Contra el Cáncer del Ecuador","has_results":false},{"nct_id":"NCT04859543","title":"Pediatric Prospective Personalized Immune and Target Identification Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Masaryk University","has_results":false},{"nct_id":"NCT03434262","title":"SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":68,"lead_sponsor_name":"St. Jude Children's Research Hospital","has_results":false},{"nct_id":"NCT03257631","title":"A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":53,"lead_sponsor_name":"Celgene","has_results":true},{"nct_id":"NCT01931098","title":"Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":true},{"nct_id":"NCT03911388","title":"HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":24,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false},{"nct_id":"NCT06322342","title":"Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"Reveal Pharmaceuticals Inc.","has_results":false},{"nct_id":"NCT03435952","title":"Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT","phase":"PHASE1","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":18,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false},{"nct_id":"NCT04096716","title":"Mapping Draining Lymph Nodes in CNS Malignancies","phase":"PHASE1","overall_status":"TERMINATED","enrollment_count":14,"lead_sponsor_name":"Washington University School of Medicine","has_results":false},{"nct_id":"NCT02692898","title":"Biomarker Analysis of Central Nervous System Tumors","phase":"","overall_status":"TERMINATED","enrollment_count":12,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":false},{"nct_id":"NCT02095353","title":"Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients","phase":"","overall_status":"TERMINATED","enrollment_count":6,"lead_sponsor_name":"University of Nebraska","has_results":false},{"nct_id":"NCT03188354","title":"Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma","phase":"NA","overall_status":"COMPLETED","enrollment_count":3,"lead_sponsor_name":"Norwegian University of Science and Technology","has_results":false},{"nct_id":"NCT04525014","title":"RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors","phase":"PHASE1","overall_status":"TERMINATED","enrollment_count":2,"lead_sponsor_name":"EpicentRx, Inc.","has_results":false},{"nct_id":"NCT03530605","title":"Use of Optune TTF With Radiation as an Alternative for Elderly Patients With Primary CNS Lymphoma","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Saint Luke's Health System","has_results":false},{"nct_id":"NCT05064306","title":"131I-omburtamab for the Treatment of Central Nervous System/Leptomeningeal Neoplasms in Children and Young Adults","phase":"","overall_status":"NO_LONGER_AVAILABLE","enrollment_count":null,"lead_sponsor_name":"Memorial Sloan Kettering Cancer Center","has_results":false},{"nct_id":"NCT05511714","title":"Expanded Access [11C] Methionine PET Imaging","phase":"","overall_status":"AVAILABLE","enrollment_count":null,"lead_sponsor_name":"St. Jude Children's Research Hospital","has_results":false}],"total":21},"guidelines":[],"source":"Drug Landscape verified database"}