{"disease":{"id":"cataract","name":"cataract"},"drugs":{"marketed":[{"drug_id":"bromfenac-ophthalmic-solution","indication_name":"Postoperative inflammation and ocular pain after cataract surgery","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"bromfenac ophthalmic solution","company_name":"Bausch & Lomb Incorporated","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":9,"revenue":null,"mechanism":null},{"drug_id":"chymotrypsin","indication_name":"Cataract surgery","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Zolyse","generic_name":"CHYMOTRYPSIN","company_name":"Novartis","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":17,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05197660","title":"Routine Surgical Procedures During COVID-19 Pandemic: a French Nationwide Cohort Study","phase":"","overall_status":"COMPLETED","enrollment_count":2000000,"lead_sponsor_name":"EPI-PHARE","has_results":false},{"nct_id":"NCT03455478","title":"Shanghai Eye Study for Adults","phase":"NA","overall_status":"RECRUITING","enrollment_count":1000000,"lead_sponsor_name":"Shanghai Eye Disease Prevention and Treatment Center","has_results":false},{"nct_id":"NCT06616506","title":"Artificial Intelligence for Highly Myopic Cataract","phase":"","overall_status":"RECRUITING","enrollment_count":500000,"lead_sponsor_name":"Shanghai High Myopia Study Group","has_results":false},{"nct_id":"NCT03062085","title":"Shanghai High Myopia Study","phase":"","overall_status":"RECRUITING","enrollment_count":60000,"lead_sponsor_name":"Shanghai High Myopia Study Group","has_results":false},{"nct_id":"NCT07227714","title":"Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":40000,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT04340635","title":"Multi-center Ocular Biological Parameters Study","phase":"","overall_status":"UNKNOWN","enrollment_count":20000,"lead_sponsor_name":"Aier School of Ophthalmology, Central South University","has_results":false},{"nct_id":"NCT06092164","title":"Visual Outcomes of Functional Intraocular Lenses in Cataracts","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":20000,"lead_sponsor_name":"Eye & ENT Hospital of Fudan University","has_results":false},{"nct_id":"NCT03470584","title":"Vegetarian Diet and Chronic Degenerative Diseases","phase":"","overall_status":"COMPLETED","enrollment_count":18064,"lead_sponsor_name":"Dalin Tzu Chi General Hospital","has_results":false},{"nct_id":"NCT03278587","title":"Village-Integrated Eye Worker Trial II - Pilot","phase":"NA","overall_status":"COMPLETED","enrollment_count":16075,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT07497815","title":"Artificial Intelligence-assisted Diagnosis in Ophthalmology","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":15000,"lead_sponsor_name":"Marisse Masis-Solano","has_results":false},{"nct_id":"NCT05194696","title":"Caffeine Consumption and Cataract Prevention","phase":"","overall_status":"UNKNOWN","enrollment_count":12000,"lead_sponsor_name":"Vienna Institute for Research in Ocular Surgery","has_results":false},{"nct_id":"NCT03047369","title":"The Myelin Disorders Biorepository Project","phase":"","overall_status":"RECRUITING","enrollment_count":12000,"lead_sponsor_name":"Children's Hospital of Philadelphia","has_results":false},{"nct_id":"NCT04992403","title":"Ocular Biometrics in a French Population","phase":"","overall_status":"COMPLETED","enrollment_count":11650,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04187157","title":"Association Between Light Spectrum and Survival After Cataract Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":10192,"lead_sponsor_name":"University of Pittsburgh","has_results":false},{"nct_id":"NCT03063216","title":"Shanghai Pediatric Cataract Study","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Evidence Based Cataract Study Group","has_results":false},{"nct_id":"NCT00342342","title":"Family Studies of Eye Traits","phase":"","overall_status":"COMPLETED","enrollment_count":7370,"lead_sponsor_name":"National Human Genome Research Institute (NHGRI)","has_results":false},{"nct_id":"NCT06112431","title":"Eye Health Intervention Study in Upper Manhattan","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":5840,"lead_sponsor_name":"Columbia University","has_results":false},{"nct_id":"NCT04732351","title":"Evaluation of the Active Sentry System During Cataract Surgery With the Centurion Phacoemulsifier","phase":"","overall_status":"COMPLETED","enrollment_count":5000,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT05472844","title":"The Cohort Study of Pediatric Cataract","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Zhongshan Ophthalmic Center, Sun Yat-sen University","has_results":false},{"nct_id":"NCT04763785","title":"Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images","phase":"","overall_status":"UNKNOWN","enrollment_count":4800,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT04143334","title":"Prevalence of Blindness, Visual Impairment in Chao Nan Area, China","phase":"","overall_status":"COMPLETED","enrollment_count":3700,"lead_sponsor_name":"Chinese University of Hong Kong","has_results":false},{"nct_id":"NCT00056771","title":"Clinical and Genetic Studies of Families With Congenital or Hereditary Cataracts","phase":"","overall_status":"COMPLETED","enrollment_count":3432,"lead_sponsor_name":"National Eye Institute (NEI)","has_results":false},{"nct_id":"NCT07257536","title":"Xinxing Eye Cohort Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":3000,"lead_sponsor_name":"Zhongshan Ophthalmic Center, Sun Yat-sen University","has_results":false},{"nct_id":"NCT05290870","title":"Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.","phase":"","overall_status":"COMPLETED","enrollment_count":2183,"lead_sponsor_name":"Teleon Surgical B.V.","has_results":false},{"nct_id":"NCT03215186","title":"Non-genetic Risk Factors of Congenital Cataracts","phase":"","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT07022444","title":"Research Based on IOLMaster700 Cataract Diagnosis and Classification System","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Shanghai 10th People's Hospital","has_results":false},{"nct_id":"NCT07333248","title":"Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural Assam","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Seva Canada Society","has_results":false},{"nct_id":"NCT05394324","title":"A Post-market Clinical Study to Collect Safety and Performance Data on Johnson & Johnson Surgical Vision Products","phase":"","overall_status":"COMPLETED","enrollment_count":1674,"lead_sponsor_name":"Johnson & Johnson Surgical Vision, Inc.","has_results":false},{"nct_id":"NCT01774474","title":"PRevention of Macular EDema After Cataract Surgery","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1127,"lead_sponsor_name":"Maastricht University Medical Center","has_results":false},{"nct_id":"NCT03097562","title":"Wound Architecture and Functional Outcome After Cataract Surgery With Manual vs.Femtosecond Laser Assisted Procedures","phase":"NA","overall_status":"COMPLETED","enrollment_count":1123,"lead_sponsor_name":"Maisonneuve-Rosemont Hospital","has_results":false},{"nct_id":"NCT04104256","title":"Using Behavioral Economics to Reduce Low-Value Care","phase":"NA","overall_status":"COMPLETED","enrollment_count":1045,"lead_sponsor_name":"University of California, Los Angeles","has_results":true},{"nct_id":"NCT05779319","title":"1000 Eyes Lens Biometry Study: Artificial Intelligence for Intraocular Lens Power Calculation","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Johannes Kepler University of Linz","has_results":false},{"nct_id":"NCT06182605","title":"Multifunctional Cataract Surgery Assistive Instruments Used in Cataract Surgery","phase":"NA","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT05690893","title":"Crystalline Lens Tilt Evaluation Using Swept-source Optical Coherence Tomography","phase":"","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"Johannes Kepler University of Linz","has_results":false},{"nct_id":"NCT01982006","title":"Economic Evaluation of Femtosecond Laser Assisted Cataract Surgery","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":920,"lead_sponsor_name":"University Hospital, Bordeaux","has_results":false},{"nct_id":"NCT04328207","title":"Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits","phase":"NA","overall_status":"COMPLETED","enrollment_count":900,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":true},{"nct_id":"NCT03400124","title":"Cost-effectiveness of ISBCS vs. DSBCS","phase":"NA","overall_status":"COMPLETED","enrollment_count":858,"lead_sponsor_name":"Maastricht University Medical Center","has_results":false},{"nct_id":"NCT03739528","title":"Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":808,"lead_sponsor_name":"NTC srl","has_results":true},{"nct_id":"NCT03992807","title":"A Decision Aid for Patients With Age-related Cataract","phase":"NA","overall_status":"UNKNOWN","enrollment_count":773,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT00925600","title":"Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":769,"lead_sponsor_name":"Amgen","has_results":true},{"nct_id":"NCT04271709","title":"Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT)","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":749,"lead_sponsor_name":"Columbia University","has_results":false},{"nct_id":"NCT03367767","title":"Age-Related Eye Disease Study 2 (AREDS2) 10-year Follow-On","phase":"","overall_status":"COMPLETED","enrollment_count":709,"lead_sponsor_name":"National Eye Institute (NEI)","has_results":false},{"nct_id":"NCT03525015","title":"Impact of a Printed Decision Aid on Cataract Surgery Choice","phase":"NA","overall_status":"UNKNOWN","enrollment_count":696,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT04246346","title":"Effectiveness of Using Interactive Consulting System to Enhance Informed Choice","phase":"NA","overall_status":"UNKNOWN","enrollment_count":660,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT03653520","title":"Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)","phase":"NA","overall_status":"COMPLETED","enrollment_count":651,"lead_sponsor_name":"Avanti Anesthesia","has_results":false},{"nct_id":"NCT06356324","title":"The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":650,"lead_sponsor_name":"Montefiore Medical Center","has_results":false},{"nct_id":"NCT05158699","title":"Effectiveness of Periocular Drug Injection in CATaract Surgery","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":628,"lead_sponsor_name":"Luigi Rondas","has_results":false},{"nct_id":"NCT05287269","title":"Ocular Coherence Tomography During Cataract Assessment","phase":"","overall_status":"COMPLETED","enrollment_count":626,"lead_sponsor_name":"Brighton and Sussex University Hospitals NHS Trust","has_results":false},{"nct_id":"NCT03152747","title":"Influence of Posterior Vitreous Detachment on Retinal Detachment After Lens Surgery in Myopic Eyes","phase":"","overall_status":"COMPLETED","enrollment_count":609,"lead_sponsor_name":"Prim. Prof. Dr. Oliver Findl, MBA","has_results":false},{"nct_id":"NCT07087275","title":"Long-term Visual and Refractive Outcomes After Traumatic Cataract Surgery in Children","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":600,"lead_sponsor_name":"Jin Yang","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}