{"disease":{"id":"cardiac-disease","name":"cardiac disease"},"drugs":{"marketed":[{"drug_id":"dobutamine-hydrochloride","indication_name":"Organic Cardiac Disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Dobutamine Hydrochloride In Dextrose 5% In Plastic Container","generic_name":"Dobutamine Hydrochloride","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"Beta-receptors of the heart","drug_class":"Inotropic agent","quality_score":10,"revenue":null,"mechanism":"Direct-acting inotropic agent stimulating cardiac beta-receptors with mild chronotropic and vasodilative effects."},{"drug_id":"dobutamine","indication_name":"Organic Cardiac Disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Dobutamine Hydrochloride In Dextrose 5% In Plastic Container","generic_name":"DOBUTAMINE","company_name":"","drug_phase":"marketed","molecular_target":"Beta-2 adrenergic receptor","drug_class":"beta-Adrenergic Agonist","quality_score":49,"revenue":null,"mechanism":""},{"drug_id":"dobutamin","indication_name":"Organic Cardiac Disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Dobutamin","company_name":"Competence Network for Congenital Heart Defects","drug_phase":"discontinued","molecular_target":"Solute carrier family 22 member 1, Alpha-1D adrenergic receptor, Alpha-2B adrenergic receptor","drug_class":"","quality_score":null,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":3,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04053335","title":"Smarter Care Virginia, Examining Low-Value Care in Virginia","phase":"","overall_status":"COMPLETED","enrollment_count":5000000,"lead_sponsor_name":"University of California, Los Angeles","has_results":false},{"nct_id":"NCT06881797","title":"Unrecognised Comorbidity Detection in Hospitalised Patients","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":4500000,"lead_sponsor_name":"University of Oxford","has_results":false},{"nct_id":"NCT05837364","title":"Predicting Risk of Atrial Fibrillation and Association With Other Diseases","phase":"","overall_status":"COMPLETED","enrollment_count":2159663,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT06409481","title":"Pharmacovigilance Assessment of Reporting of Cardiovascular Adverse Events With Antineoplastic Agents (PARCA)","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":800000,"lead_sponsor_name":"The First Affiliated Hospital of Xinxiang Medical College","has_results":false},{"nct_id":"NCT03530215","title":"Evaluation of Reporting of Cardio-vascular Adverse Events With Antineoplastic and Immunomodulating Agents (EROCA)","phase":"","overall_status":"COMPLETED","enrollment_count":500000,"lead_sponsor_name":"Groupe Hospitalier Pitie-Salpetriere","has_results":false},{"nct_id":"NCT05214573","title":"Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk","phase":"","overall_status":"COMPLETED","enrollment_count":386301,"lead_sponsor_name":"Mayo Clinic","has_results":true},{"nct_id":"NCT03413176","title":"Evaluation of Reporting of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor Inhibitors Associated Cardiovascular Adverse reactioN.","phase":"","overall_status":"COMPLETED","enrollment_count":150000,"lead_sponsor_name":"Groupe Hospitalier Pitie-Salpetriere","has_results":false},{"nct_id":"NCT05961748","title":"Registry of Multicenter Brain-Heart Comorbidity in China","phase":"","overall_status":"RECRUITING","enrollment_count":100000,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT04584645","title":"A Digital Flu Intervention for People With Cardiovascular Conditions","phase":"NA","overall_status":"COMPLETED","enrollment_count":49138,"lead_sponsor_name":"Evidation Health","has_results":true},{"nct_id":"NCT03946410","title":"Danish Cardiovascular Screening Trial II","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":38000,"lead_sponsor_name":"Odense University Hospital","has_results":false},{"nct_id":"NCT03394859","title":"Electronic Medical Records and Genomics (eMERGE) Phase III","phase":"","overall_status":"COMPLETED","enrollment_count":25380,"lead_sponsor_name":"Vanderbilt University Medical Center","has_results":false},{"nct_id":"NCT06001073","title":"Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics","phase":"","overall_status":"RECRUITING","enrollment_count":25000,"lead_sponsor_name":"First Affiliated Hospital Xi'an Jiaotong University","has_results":false},{"nct_id":"NCT04963218","title":"A Multi-Center Study of Detection of Low Ventricular Ejection Fraction","phase":"","overall_status":"COMPLETED","enrollment_count":16000,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT07038018","title":"External Validation of Artificial Intelligence-enabled Electrocardiography (AI-ECG) for the Detection of Left Ventricular Dysfunction (LVD)","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":12500,"lead_sponsor_name":"Tri-Service General Hospital","has_results":false},{"nct_id":"NCT04823663","title":"BoStOn SCientific Rhythm MAnagemenT REgiStry (SOCRATES)","phase":"","overall_status":"RECRUITING","enrollment_count":12500,"lead_sponsor_name":"Boston Scientific Corporation","has_results":false},{"nct_id":"NCT06324682","title":"ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","phase":"","overall_status":"RECRUITING","enrollment_count":8400,"lead_sponsor_name":"University Hospital of Ferrara","has_results":false},{"nct_id":"NCT04492384","title":"Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients","phase":"","overall_status":"COMPLETED","enrollment_count":6396,"lead_sponsor_name":"Eurasian Association of Therapists","has_results":false},{"nct_id":"NCT03899298","title":"Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions","phase":"PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":5000,"lead_sponsor_name":"R3 Stem Cell","has_results":false},{"nct_id":"NCT04407780","title":"Cardio-Oncology Registry","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"European Georges Pompidou Hospital","has_results":false},{"nct_id":"NCT03946956","title":"Fighting Social Inequality in Cardiovascular Health I","phase":"NA","overall_status":"COMPLETED","enrollment_count":5000,"lead_sponsor_name":"Odense University Hospital","has_results":false},{"nct_id":"NCT05829993","title":"Development of an Artificial Intelligence Algorithm to Detect Pathological Repolarization Disorders on the ECG and the Risk of Ventricular Arrhythmias","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT02996903","title":"Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017","phase":"","overall_status":"COMPLETED","enrollment_count":4502,"lead_sponsor_name":"LMU Klinikum","has_results":false},{"nct_id":"NCT06804499","title":"Tampere Coronary Artery Disease and Sudden Cardiac Arrest Study","phase":"","overall_status":"RECRUITING","enrollment_count":4000,"lead_sponsor_name":"Tampere Heart Hospital","has_results":false},{"nct_id":"NCT05378139","title":"Continuous Wireless Monitoring of Vital Signs and Automated Alerts in Participants at Home and During Hospitalization","phase":"","overall_status":"RECRUITING","enrollment_count":3095,"lead_sponsor_name":"University Hospital Bispebjerg and Frederiksberg","has_results":false},{"nct_id":"NCT05189847","title":"Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis","phase":"","overall_status":"COMPLETED","enrollment_count":3059,"lead_sponsor_name":"Eurasian Association of Therapists","has_results":false},{"nct_id":"NCT05897710","title":"Virtual World-Based Cardiac Rehabilitation","phase":"NA","overall_status":"COMPLETED","enrollment_count":2881,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT05476991","title":"Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":2800,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04031989","title":"Repository of Phase Signals for Pulmonary Hypertension Algorithm Development","phase":"NA","overall_status":"UNKNOWN","enrollment_count":2500,"lead_sponsor_name":"Analytics For Life","has_results":false},{"nct_id":"NCT07370831","title":"Incidence and Prognostic of Cardiac Surgery-Associated Acute Kidney Injury: A Spanish Multicenter Study (SCARS-AKI)","phase":"","overall_status":"COMPLETED","enrollment_count":2500,"lead_sponsor_name":"Universidad de Oviedo","has_results":false},{"nct_id":"NCT02668250","title":"Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality","phase":"NA","overall_status":"COMPLETED","enrollment_count":2495,"lead_sponsor_name":"Centre Hospitalier Universitaire de Saint Etienne","has_results":false},{"nct_id":"NCT03579641","title":"Precision Event Monitoring for Patients With Heart Failure Using HeartLogic","phase":"","overall_status":"COMPLETED","enrollment_count":2184,"lead_sponsor_name":"Boston Scientific Corporation","has_results":false},{"nct_id":"NCT05002543","title":"CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting","phase":"","overall_status":"RECRUITING","enrollment_count":2150,"lead_sponsor_name":"Corcym S.r.l","has_results":false},{"nct_id":"NCT05452356","title":"Testing VIRTUES Patient Care Sets in Cardiac Patients (VIRTUES Cardiac Care)","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","has_results":false},{"nct_id":"NCT07150780","title":"Benefits of no Fasting Compared to Fasting Prior to Elective Cardiac Catheterization: A Single-center Randomized-controlled Trial","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Munson Medical Center","has_results":false},{"nct_id":"NCT05055830","title":"Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT03786965","title":"Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures.","phase":"NA","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"St. Petersburg State Pavlov Medical University","has_results":false},{"nct_id":"NCT07012668","title":"Outcomes and Risk Factors of Different Treatment Strategies for Neuro-co-cardiological Diseases and Post-cardiac Surgery Cerebrovascular Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT04609228","title":"Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors","phase":"","overall_status":"UNKNOWN","enrollment_count":1911,"lead_sponsor_name":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","has_results":false},{"nct_id":"NCT07335042","title":"Prediction Model for MINS After Major Hepatobiliary Surgery","phase":"","overall_status":"RECRUITING","enrollment_count":1800,"lead_sponsor_name":"Beijing Tsinghua Chang Gung Hospital","has_results":false},{"nct_id":"NCT07094737","title":"The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart Failure","phase":"","overall_status":"RECRUITING","enrollment_count":1600,"lead_sponsor_name":"Fondazione Don Carlo Gnocchi Onlus","has_results":false},{"nct_id":"NCT04129073","title":"QUality Of Life and surviVAl in carDIac arreSt Patients","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1600,"lead_sponsor_name":"Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva","has_results":false},{"nct_id":"NCT06332547","title":"Transfusion in Cardiac Valve Surgery","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":1600,"lead_sponsor_name":"Guangdong Provincial People's Hospital","has_results":false},{"nct_id":"NCT03098524","title":"Low Tidal MEChanical Ventilation Against NO Ventilation During Cardiopulmonary Bypass Heart Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":1502,"lead_sponsor_name":"CMC Ambroise Paré","has_results":false},{"nct_id":"NCT05647577","title":"The Relationship Between Inflammatory ARTritis and CArdiac DIseAse","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1285,"lead_sponsor_name":"University Hospital, Gentofte, Copenhagen","has_results":false},{"nct_id":"NCT05308719","title":"Nasal Oxygen Therapy After Cardiac Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":1280,"lead_sponsor_name":"Papworth Hospital NHS Foundation Trust","has_results":false},{"nct_id":"NCT03833843","title":"Sudden Cardiac Death in Systemic Right Ventricle","phase":"","overall_status":"COMPLETED","enrollment_count":1240,"lead_sponsor_name":"European Georges Pompidou Hospital","has_results":false},{"nct_id":"NCT06321900","title":"Personalized Risk Prediction of Sudden Cardiac Death","phase":"","overall_status":"UNKNOWN","enrollment_count":1050,"lead_sponsor_name":"Istituto Auxologico Italiano","has_results":false},{"nct_id":"NCT05443321","title":"Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1006,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT03902223","title":"Routine Cardiac Screening in Sarcoidosis Patients","phase":"","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"Foundation for Sarcoidosis Research","has_results":false},{"nct_id":"NCT07336394","title":"Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance Techniques","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Chinese Academy of Medical Sciences, Fuwai Hospital","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}