{"disease":{"id":"bronchopulmonary-dysplasia","name":"bronchopulmonary dysplasia"},"drugs":{"marketed":[{"drug_id":"rsvpref-vaccine","indication_name":"Prevention of severe lower respiratory tract disease caused by respiratory syncytial virus (RSV) in young children with a history of premature birth or bronchopulmonary dysplasia.","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"RSVpreF Vaccine","generic_name":"rsvpref-vaccine","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"RSV","drug_class":"vaccine","quality_score":22,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05181319","title":"Prediction for Bronchopulmonary Dysplasia","phase":"","overall_status":"UNKNOWN","enrollment_count":5000,"lead_sponsor_name":"Kai Mu","has_results":false},{"nct_id":"NCT03850457","title":"Epidemiological Study for Bronchopulmonary Dysplasia (BPD) in China","phase":"","overall_status":"COMPLETED","enrollment_count":3800,"lead_sponsor_name":"Children's Hospital of Fudan University","has_results":false},{"nct_id":"NCT03808402","title":"The Effect of Surfactant Dose on Outcomes in Preterm Infants With RDS","phase":"","overall_status":"COMPLETED","enrollment_count":2973,"lead_sponsor_name":"Chiesi UK","has_results":false},{"nct_id":"NCT06443528","title":"Comparison of Lung Ultrasound Scores With Clinical Models for Predicting Bronchopulmonary Dysplasia：A Multi-center Prospective Cohort Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1620,"lead_sponsor_name":"The First Hospital of Jilin University","has_results":false},{"nct_id":"NCT06082414","title":"Systemic Management in Extremely Preterm and Extremely Low Birth Weight Infants","phase":"","overall_status":"COMPLETED","enrollment_count":1200,"lead_sponsor_name":"Peking University","has_results":false},{"nct_id":"NCT01780155","title":"Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity","phase":"","overall_status":"COMPLETED","enrollment_count":1068,"lead_sponsor_name":"National Institute of Environmental Health Sciences (NIEHS)","has_results":false},{"nct_id":"NCT06552455","title":"Post-extubation Pressures in Preterm Neonates: A CER Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1050,"lead_sponsor_name":"McMaster Children's Hospital","has_results":false},{"nct_id":"NCT07052201","title":"Dexamethasone Regimens for BPD Prevention in Preterm Infants","phase":"PHASE3","overall_status":"NOT_YET_RECRUITING","enrollment_count":970,"lead_sponsor_name":"The Children's Hospital of Zhejiang University School of Medicine","has_results":false},{"nct_id":"NCT07417111","title":"Continued Pressure for Alveolar Protection (CPAP Trial)","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":860,"lead_sponsor_name":"NICHD Neonatal Research Network","has_results":false},{"nct_id":"NCT01353313","title":"Hydrocortisone for BPD","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":800,"lead_sponsor_name":"NICHD Neonatal Research Network","has_results":true},{"nct_id":"NCT05849077","title":"Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)","phase":"NA","overall_status":"RECRUITING","enrollment_count":700,"lead_sponsor_name":"University of Texas Southwestern Medical Center","has_results":false},{"nct_id":"NCT04545866","title":"The Budesonide in Babies (BiB) Trial","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":642,"lead_sponsor_name":"NICHD Neonatal Research Network","has_results":true},{"nct_id":"NCT03411018","title":"Respiratory Management of Preterm Infants and Bronchopulmonary Dysplasia","phase":"","overall_status":"COMPLETED","enrollment_count":600,"lead_sponsor_name":"Manuel Sanchez Luna","has_results":false},{"nct_id":"NCT06045130","title":"PUFAs in Preterm Infants","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":600,"lead_sponsor_name":"The First Hospital of Jilin University","has_results":false},{"nct_id":"NCT06940856","title":"Chloride Imbalance in Preterm Infants","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":500,"lead_sponsor_name":"Kanuni Sultan Suleyman Training and Research Hospital","has_results":false},{"nct_id":"NCT05446272","title":"The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial","phase":"NA","overall_status":"RECRUITING","enrollment_count":478,"lead_sponsor_name":"University of Pennsylvania","has_results":false},{"nct_id":"NCT03372525","title":"Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"Daping Hospital and the Research Institute of Surgery of the Third Military Medical University","has_results":false},{"nct_id":"NCT05055193","title":"Outcome of Extremely Preterm Infants Who Received Systemic Postnatal Corticosteroid for Bronchopulmonary Dysplasia","phase":"","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT05711966","title":"Comparison of INRECSURE and LISA in Preterm Neonates With RDS","phase":"NA","overall_status":"UNKNOWN","enrollment_count":381,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT06897839","title":"Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD)","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":366,"lead_sponsor_name":"Airway Therapeutics, Inc.","has_results":false},{"nct_id":"NCT04050488","title":"Zinc Supplementation on Very Low Birth Weight Infant","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":364,"lead_sponsor_name":"Fakultas Kedokteran Universitas Indonesia","has_results":false},{"nct_id":"NCT07377955","title":"Combined Oscillation-Volume guarantEe Study","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":348,"lead_sponsor_name":"Xingwang Zhu","has_results":false},{"nct_id":"NCT03253263","title":"A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":338,"lead_sponsor_name":"OHB Neonatology Ltd.","has_results":false},{"nct_id":"NCT05618769","title":"Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants","phase":"NA","overall_status":"UNKNOWN","enrollment_count":330,"lead_sponsor_name":"Franciscus Gasthuis","has_results":false},{"nct_id":"NCT06065215","title":"Early-life MRI Biomarkers of Longer-term Respiratory Morbidity in Infants Born Extremely Preterm (EMBLEM)","phase":"","overall_status":"RECRUITING","enrollment_count":319,"lead_sponsor_name":"Children's Hospital of Eastern Ontario","has_results":false},{"nct_id":"NCT03275415","title":"Intratracheal Budesonide/Surfactant Prevents BPD","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":310,"lead_sponsor_name":"Taipei Medical University","has_results":false},{"nct_id":"NCT04984057","title":"Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome","phase":"NA","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Daping Hospital and the Research Institute of Surgery of the Third Military Medical University","has_results":false},{"nct_id":"NCT04237844","title":"Clinic Features and Outcome of BPD (SGBPD)","phase":"","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Wang Jianhui","has_results":false},{"nct_id":"NCT03717584","title":"A Cohort Study of the Intestinal Microbiota of Premature Infants","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":300,"lead_sponsor_name":"University of California, Davis","has_results":false},{"nct_id":"NCT06279741","title":"Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":265,"lead_sponsor_name":"EXO Biologics S.A.","has_results":false},{"nct_id":"NCT04163822","title":"Analysis of BPD in Premature Infants With Typical Imaging Changes","phase":"","overall_status":"COMPLETED","enrollment_count":256,"lead_sponsor_name":"Wang Jianhui","has_results":true},{"nct_id":"NCT04107701","title":"Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD","phase":"","overall_status":"UNKNOWN","enrollment_count":240,"lead_sponsor_name":"Boston Children's Hospital","has_results":false},{"nct_id":"NCT04077333","title":"MISA to NRDS：a Multicenter Study in China","phase":"NA","overall_status":"COMPLETED","enrollment_count":237,"lead_sponsor_name":"Peking University Third Hospital","has_results":false},{"nct_id":"NCT06915441","title":"Lipid Infusions to Optimize Nutrition Trial","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":230,"lead_sponsor_name":"The University of Texas Health Science Center, Houston","has_results":false},{"nct_id":"NCT05568264","title":"Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit","phase":"NA","overall_status":"RECRUITING","enrollment_count":222,"lead_sponsor_name":"Shirley Ryan AbilityLab","has_results":false},{"nct_id":"NCT04209088","title":"Interest of Pulmonary Ultrasound to Predict Evolution Towards Bronchopulmonary Dysplasia in Premature Infants at Gestational Age Less Than or Equal to 34 Weeks of Gestation","phase":"NA","overall_status":"UNKNOWN","enrollment_count":218,"lead_sponsor_name":"University Hospital, Limoges","has_results":false},{"nct_id":"NCT06000761","title":"Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit","phase":"NA","overall_status":"RECRUITING","enrollment_count":218,"lead_sponsor_name":"University of Florida","has_results":false},{"nct_id":"NCT02475434","title":"Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants","phase":"NA","overall_status":"COMPLETED","enrollment_count":210,"lead_sponsor_name":"Baylor College of Medicine","has_results":false},{"nct_id":"NCT04239690","title":"Preservation of Blood in Extremely Preterm Infants","phase":"NA","overall_status":"COMPLETED","enrollment_count":201,"lead_sponsor_name":"David Ley","has_results":false},{"nct_id":"NCT03775785","title":"Targeted vs Standard Fortification of Breast Milk","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Princess Anna Mazowiecka Hospital, Warsaw, Poland","has_results":false},{"nct_id":"NCT04184648","title":"Comparison of Classification Standards of BPD in Premature Infants","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Wang Jianhui","has_results":false},{"nct_id":"NCT04905732","title":"Nasal High-frequency Oscillatory Ventilation (NHFOV) for Ventilated Newborn Infants With BPD","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Daping Hospital and the Research Institute of Surgery of the Third Military Medical University","has_results":false},{"nct_id":"NCT03229967","title":"Gastrointestinal Microbiome Influence on the Development of Bronchopulmonary Dysplasia","phase":"","overall_status":"COMPLETED","enrollment_count":197,"lead_sponsor_name":"University of Tennessee","has_results":false},{"nct_id":"NCT03014453","title":"GER Poses a Potential Risk for Late Complications of BPD","phase":"","overall_status":"COMPLETED","enrollment_count":187,"lead_sponsor_name":"Shengjing Hospital","has_results":true},{"nct_id":"NCT04971694","title":"Impact of Steroid, Diuretic, and Fluid Use on BPD Outcomes","phase":"","overall_status":"COMPLETED","enrollment_count":175,"lead_sponsor_name":"Pediatrix","has_results":false},{"nct_id":"NCT05944055","title":"25OH Vitamin D Overdoses and Risk of Bronchopulmonary Dysplasia or Death","phase":"","overall_status":"UNKNOWN","enrollment_count":173,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT07058025","title":"Mesenchymal Stromal Cell Therapy to Prevent Bronchopulmonary Dysplasia in Extreme Preterm Infants","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":168,"lead_sponsor_name":"Ottawa Hospital Research Institute","has_results":false},{"nct_id":"NCT03657693","title":"MRI in BPD Subjects","phase":"","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT05152875","title":"Relationship Between Fungal Colonization and Severe Bronchopulmonary Dysplasia","phase":"","overall_status":"COMPLETED","enrollment_count":153,"lead_sponsor_name":"Centre Hospitalier Sud Francilien","has_results":false},{"nct_id":"NCT04756297","title":"Lung Ultrasound for Prediction of Bronchopulmonary Dysplasia","phase":"","overall_status":"COMPLETED","enrollment_count":152,"lead_sponsor_name":"Adel Mohamed","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}