{"disease":{"id":"breast-cancers","name":"breast cancers"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03987633","title":"EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality","phase":"","overall_status":"RECRUITING","enrollment_count":200000,"lead_sponsor_name":"Future Genetics Limited","has_results":false},{"nct_id":"NCT03667417","title":"Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Institut Paoli-Calmettes","has_results":false},{"nct_id":"NCT06805812","title":"Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study","phase":"","overall_status":"RECRUITING","enrollment_count":3500,"lead_sponsor_name":"Fondazione IRCCS Istituto Nazionale dei Tumori, Milano","has_results":false},{"nct_id":"NCT06606730","title":"Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":2454,"lead_sponsor_name":"UNICANCER","has_results":false},{"nct_id":"NCT06628388","title":"Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong","phase":"NA","overall_status":"RECRUITING","enrollment_count":1728,"lead_sponsor_name":"The University of Hong Kong","has_results":false},{"nct_id":"NCT03896958","title":"The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"SpeciCare","has_results":false},{"nct_id":"NCT04025541","title":"Analysis of Circulating Tumor Markers in Blood","phase":"NA","overall_status":"RECRUITING","enrollment_count":992,"lead_sponsor_name":"Institut du Cancer de Montpellier - Val d'Aurelle","has_results":false},{"nct_id":"NCT06960291","title":"Sustainable Implementation of the EXCEL Exercise Oncology Program Across Canada","phase":"NA","overall_status":"RECRUITING","enrollment_count":740,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT03797326","title":"Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":611,"lead_sponsor_name":"Merck Sharp & Dohme LLC","has_results":true},{"nct_id":"NCT02568267","title":"Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":534,"lead_sponsor_name":"Hoffmann-La Roche","has_results":false},{"nct_id":"NCT06711939","title":"Vocorder Device Validation in Clinical Settings - Continuous Monitoring of Individuals (Vocorder Clinical Validation-VCV)","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":515,"lead_sponsor_name":"Mitera Hospital","has_results":false},{"nct_id":"NCT01631552","title":"Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":515,"lead_sponsor_name":"Gilead Sciences","has_results":true},{"nct_id":"NCT06825975","title":"A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Triple-Negative and HER2+ Breast Cancer Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":348,"lead_sponsor_name":"Guangdong Provincial People's Hospital","has_results":false},{"nct_id":"NCT02664389","title":"Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation","phase":"NA","overall_status":"COMPLETED","enrollment_count":289,"lead_sponsor_name":"University Hospital, Rouen","has_results":false},{"nct_id":"NCT03412877","title":"Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":285,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":false},{"nct_id":"NCT03289962","title":"A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":272,"lead_sponsor_name":"Genentech, Inc.","has_results":false},{"nct_id":"NCT02734004","title":"A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.","phase":"PHASE1, PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":264,"lead_sponsor_name":"AstraZeneca","has_results":true},{"nct_id":"NCT06819501","title":"Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":226,"lead_sponsor_name":"Guangdong Provincial People's Hospital","has_results":false},{"nct_id":"NCT06602167","title":"Electroacupuncture Combined With Self-administered Acupressure for the Prevention of Capecitabine-Associated Hand-Foot Syndrome","phase":"NA","overall_status":"RECRUITING","enrollment_count":220,"lead_sponsor_name":"Affiliated Hospital of Qinghai University","has_results":false},{"nct_id":"NCT07108517","title":"A Manualized Post-Traumatic Growth Intervention for People With Cancer in Greece - IC-Growth","phase":"NA","overall_status":"RECRUITING","enrollment_count":180,"lead_sponsor_name":"Centre for Research and Technology Hellas","has_results":false},{"nct_id":"NCT06811870","title":"A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Breast Cancer Patients","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":161,"lead_sponsor_name":"Guangdong Provincial People's Hospital","has_results":false},{"nct_id":"NCT02266420","title":"Comparison of Biological Features Between pN0 Triple Negative Breast Tumours With Size < or = 10 mm (pT1a/b) Versus pT1c T2 < or = 30 mm","phase":"NA","overall_status":"COMPLETED","enrollment_count":151,"lead_sponsor_name":"Institut Claudius Regaud","has_results":false},{"nct_id":"NCT06835426","title":"High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins","phase":"NA","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Algemeen Ziekenhuis Maria Middelares","has_results":false},{"nct_id":"NCT07038369","title":"A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations","phase":"PHASE1","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":134,"lead_sponsor_name":"Atavistik Bio, Inc","has_results":false},{"nct_id":"NCT05086692","title":"A Beta-only IL-2 ImmunoTherapY Study","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":115,"lead_sponsor_name":"Medicenna Therapeutics, Inc.","has_results":false},{"nct_id":"NCT07095023","title":"Neoadjuvant Oral Paclitaxel Plus Subcutaneous Pertuzumab/Trastuzumab in Patients With HER2-positive Breast Cancer","phase":"NA","overall_status":"RECRUITING","enrollment_count":112,"lead_sponsor_name":"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","has_results":false},{"nct_id":"NCT00984321","title":"A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer","phase":"NA","overall_status":"COMPLETED","enrollment_count":107,"lead_sponsor_name":"Memorial Sloan Kettering Cancer Center","has_results":false},{"nct_id":"NCT06774027","title":"Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT02045368","title":"Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":92,"lead_sponsor_name":"IGF Oncology, LLC","has_results":false},{"nct_id":"NCT06926075","title":"Early Phase Study of KESONOTIDE™in Participants With Solid Tumours","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Filamon LTD","has_results":false},{"nct_id":"NCT06910657","title":"IDOV-Immune for Advanced Solid Tumors","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":78,"lead_sponsor_name":"ViroMissile, Inc.","has_results":false},{"nct_id":"NCT06856876","title":"Examining the Effectiveness of Multidisciplinary Care Teams in Improving Outcomes for Breast Cancer Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":73,"lead_sponsor_name":"Yousaf Jan","has_results":false},{"nct_id":"NCT06433804","title":"Clinicopathological Parameters of HER2 Low Breast Cancers","phase":"","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"Vardhman Mahavir Medical College And Safdarjung Hospital","has_results":false},{"nct_id":"NCT06662864","title":"Study on Sleep, Lifestyle and Quality of Life in Women With Breast Cancer","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Institut Rafael","has_results":false},{"nct_id":"NCT02025192","title":"A Study of Tucatinib (ONT-380) Combined With Capecitabine and/or Trastuzumab in Patients With HER2+ Metastatic Breast Cancer","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Seagen Inc.","has_results":false},{"nct_id":"NCT07145827","title":"Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Uruk University","has_results":false},{"nct_id":"NCT01983501","title":"A Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":57,"lead_sponsor_name":"Seagen Inc.","has_results":false},{"nct_id":"NCT06825949","title":"A Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Hormone Receptor Positive Breast Cancer Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":55,"lead_sponsor_name":"Guangdong Provincial People's Hospital","has_results":false},{"nct_id":"NCT06956443","title":"Prediction of ICG for Skin Necrosis in Mastectomy With Immediate Reconstruction","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":50,"lead_sponsor_name":"University Medical Center Groningen","has_results":false},{"nct_id":"NCT01291420","title":"Dendritic Cell Vaccination for Patients with Solid Tumors","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":48,"lead_sponsor_name":"University Hospital, Antwerp","has_results":false},{"nct_id":"NCT06517212","title":"Tirzepatide Weight Loss for MRD+ Early Breast Cancer","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":48,"lead_sponsor_name":"Baylor Research Institute","has_results":false},{"nct_id":"NCT02576548","title":"A Phase 1/2 Study of MEDI4276 in Adults Subjects With Select HER2-expressing Advanced Solid Tumors.","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":47,"lead_sponsor_name":"MedImmune LLC","has_results":false},{"nct_id":"NCT07018505","title":"EpCAM-Targeted Surface-Enhanced Raman Spectroscopy Nanotags for Rapid Evaluation of Surgical Margins and Sentinel Lymph Node Metastasis Status in Breast Cancers","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":40,"lead_sponsor_name":"Yunnan Cancer Hospital","has_results":false},{"nct_id":"NCT05538572","title":"A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":22,"lead_sponsor_name":"Prelude Therapeutics","has_results":false},{"nct_id":"NCT06954623","title":"Partial Breast Re-irradiation for Breast Cancer","phase":"NA","overall_status":"RECRUITING","enrollment_count":20,"lead_sponsor_name":"University Hospital Heidelberg","has_results":false},{"nct_id":"NCT06943313","title":"Breast Cancer PET/CT Imaging With 68Ga-pAKTi","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":20,"lead_sponsor_name":"Fudan University","has_results":false},{"nct_id":"NCT04102436","title":"Non-Viral TCR Gene Therapy","phase":"PHASE2","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":false}],"total":47},"guidelines":[],"source":"Drug Landscape verified database"}