{"disease":{"id":"blood-loss","name":"blood loss"},"drugs":{"marketed":[{"drug_id":"meclofenamic-acid","indication_name":"Idiopathic Heavy Menstrual Blood Loss","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Meclofenamate","generic_name":"MECLOFENAMIC ACID","company_name":"","drug_phase":"marketed","molecular_target":"Prostaglandin G/H synthase 2","drug_class":"meclofenamic acid","quality_score":40,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06403163","title":"Transfusion Surveillance in Anaesthesia","phase":"","overall_status":"RECRUITING","enrollment_count":50000,"lead_sponsor_name":"Erasme University Hospital","has_results":false},{"nct_id":"NCT03578419","title":"Small-Volume Tubes to Reduce Anemia and Transfusion","phase":"NA","overall_status":"COMPLETED","enrollment_count":27411,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT03468738","title":"Investigation of the Transfusion Practices in Surgical Patients in Turkey","phase":"","overall_status":"COMPLETED","enrollment_count":6481,"lead_sponsor_name":"Diskapi Teaching and Research Hospital","has_results":false},{"nct_id":"NCT03313583","title":"French One Day Survey in 2011 - Knowing Our Population of Labile Blood Products Recipients","phase":"","overall_status":"COMPLETED","enrollment_count":4720,"lead_sponsor_name":"Etablissement Français du Sang","has_results":false},{"nct_id":"NCT03954314","title":"DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":3242,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT03278548","title":"Safety and Efficacy of 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Patients Undergoing Elective Abdominal Surgery","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":2289,"lead_sponsor_name":"Fresenius Kabi","has_results":false},{"nct_id":"NCT05783648","title":"Do Anesthesiologists Follow Guidelines on Perioperative Use of Tranexamic Acid?","phase":"","overall_status":"COMPLETED","enrollment_count":1726,"lead_sponsor_name":"Erasme University Hospital","has_results":false},{"nct_id":"NCT06189911","title":"Perioperative Blood Transfusion in Open Liver Resection","phase":"","overall_status":"COMPLETED","enrollment_count":1201,"lead_sponsor_name":"Chiang Mai University","has_results":false},{"nct_id":"NCT04431349","title":"Comparison of CABG Related Bleeding Complications in Patients Treated With Ticagrelor or Clopidogrel","phase":"","overall_status":"COMPLETED","enrollment_count":1097,"lead_sponsor_name":"Ajou University School of Medicine","has_results":false},{"nct_id":"NCT05077124","title":"Safe and Timely Antithrombotic Removal (STAR) Registry","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"CytoSorbents, Inc","has_results":false},{"nct_id":"NCT04834414","title":"CHIlled Platelet Study \"CHIPS\"","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"Philip Spinella","has_results":false},{"nct_id":"NCT06903299","title":"Prospective Investigation of Intra-Articular Tranexamic Acid Use in Elective Hip Arthroplasty","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"St. Anne's University Hospital Brno, Czech Republic","has_results":false},{"nct_id":"NCT04040023","title":"Patient Blood Management in Cardiac Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":900,"lead_sponsor_name":"Clinique Pasteur","has_results":false},{"nct_id":"NCT06414031","title":"Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":850,"lead_sponsor_name":"Ulrich Ronellenfitsch, MD","has_results":false},{"nct_id":"NCT03487341","title":"Placental Cord Drainage After Vaginal Delivery","phase":"NA","overall_status":"COMPLETED","enrollment_count":600,"lead_sponsor_name":"Ain Shams University","has_results":false},{"nct_id":"NCT06201910","title":"Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini","phase":"","overall_status":"COMPLETED","enrollment_count":575,"lead_sponsor_name":"Goethe University","has_results":false},{"nct_id":"NCT05481606","title":"Cesarean Scar Pregnancy and Clinical Outcomes","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Peking University Third Hospital","has_results":false},{"nct_id":"NCT04744181","title":"Patient Blood Management In CARdiac sUrgical patientS","phase":"","overall_status":"COMPLETED","enrollment_count":479,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT06637137","title":"Patient Blood Management in Patients Scheduled for Cardiac Surgery","phase":"","overall_status":"RECRUITING","enrollment_count":464,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT06060327","title":"Comparing Tranexamic Acid Versus Ecbolics in Preventing Hemorrhage During and After Cesarean Section","phase":"NA","overall_status":"COMPLETED","enrollment_count":440,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT04089865","title":"Oral Versus Intravenous Tranexamic Acid","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"Hospital for Special Surgery, New York","has_results":true},{"nct_id":"NCT06879353","title":"Comparison of Single-Dose Tranexamic Acid Vs. Placebo in Ovarian Cancer Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":372,"lead_sponsor_name":"Sheikh Zayed Medical College","has_results":false},{"nct_id":"NCT03284944","title":"Small-Volume Tubes to Reduce Anemia and Transfusion (STRATUS)","phase":"","overall_status":"COMPLETED","enrollment_count":369,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT05056376","title":"Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs","phase":"NA","overall_status":"COMPLETED","enrollment_count":368,"lead_sponsor_name":"Johns Hopkins University","has_results":true},{"nct_id":"NCT06822036","title":"EFFICACY of INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION on the POSTOPERATIVE BLOOD LOSS in PATIENTS UNDERGOING RARP for the TREATMENT of PROSTATE CANCER","phase":"NA","overall_status":"RECRUITING","enrollment_count":362,"lead_sponsor_name":"St. Antonius Hospital Gronau","has_results":false},{"nct_id":"NCT03152461","title":"Evaluation of the Clinical Performance of the Quantra System With the Quantra Surgical Cartridge","phase":"","overall_status":"COMPLETED","enrollment_count":302,"lead_sponsor_name":"HemoSonics LLC","has_results":false},{"nct_id":"NCT05273632","title":"Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline)","phase":"NA","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Egymedicalpedia","has_results":false},{"nct_id":"NCT06802874","title":"Maternal-fetal Outcomes of Genital Blood Loss Beyond 18 Weeks of Pregnancy","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","has_results":false},{"nct_id":"NCT04058665","title":"Hemostatic Agent Use and Intraoperative Blood Loss in Lumbar Spine Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Johns Hopkins University","has_results":false},{"nct_id":"NCT06255496","title":"QStat Cartridge in Obstetric Patients","phase":"","overall_status":"COMPLETED","enrollment_count":296,"lead_sponsor_name":"HemoSonics LLC","has_results":false},{"nct_id":"NCT06606119","title":"The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma","phase":"","overall_status":"RECRUITING","enrollment_count":275,"lead_sponsor_name":"University of Florida","has_results":false},{"nct_id":"NCT03338218","title":"Safety and Efficacy of a 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Trauma Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":238,"lead_sponsor_name":"Fresenius Kabi","has_results":false},{"nct_id":"NCT06855472","title":"The MAR Method Versus the Visual Estimation Method in Predicting External Blood Loss","phase":"NA","overall_status":"COMPLETED","enrollment_count":237,"lead_sponsor_name":"Betül Akbuğa Özel","has_results":false},{"nct_id":"NCT02403596","title":"Blood-sparing During Hip Prosthesis Surgery With Exacyl® in Patients Treated With Rivaroxaban","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":231,"lead_sponsor_name":"University Hospital, Brest","has_results":false},{"nct_id":"NCT04656067","title":"Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":230,"lead_sponsor_name":"Egymedicalpedia","has_results":false},{"nct_id":"NCT04691362","title":"Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":230,"lead_sponsor_name":"University of Liege","has_results":false},{"nct_id":"NCT05230381","title":"Intravenous Tranexamic Acid Reducing Intraoperative Blood Loss in Huge Meningiomas Resection","phase":"NA","overall_status":"UNKNOWN","enrollment_count":228,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT03952546","title":"To Evaluate the Safety and Efficacy of the Saline-coupled Bipolar Sealer in Primary Unilateral Total Knee Arthroplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":211,"lead_sponsor_name":"Northwell Health","has_results":true},{"nct_id":"NCT03984851","title":"Hemostasis Using Surgicel in Pediatric Tonsillectomy","phase":"","overall_status":"COMPLETED","enrollment_count":203,"lead_sponsor_name":"Dr. Abdul Mohsen Ibrahim Al-Turki Clinic","has_results":false},{"nct_id":"NCT04797832","title":"IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVI","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Rambam Health Care Campus","has_results":false},{"nct_id":"NCT04494126","title":"Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"College of Medical Sciences Teaching Hospital. Nepal","has_results":false},{"nct_id":"NCT04762576","title":"Thrombin in Cardiac Surgery","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"University Health Network, Toronto","has_results":false},{"nct_id":"NCT04635007","title":"Tranexamic Acid Versus Misoprostol in Reducing Blood Loss in Cesarean Section in Primigravida","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT05108597","title":"Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Pak Emirates Military Hospital","has_results":false},{"nct_id":"NCT04706221","title":"Clinical Evaluation of the CM-1500 in Postoperative Surgery Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Zynex Monitoring Solutions","has_results":true},{"nct_id":"NCT05081063","title":"Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":199,"lead_sponsor_name":"Loma Linda University","has_results":true},{"nct_id":"NCT05047133","title":"Effect of Early Administration of TXA in Adult Hip Fractures","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":170,"lead_sponsor_name":"Ascension Health","has_results":false},{"nct_id":"NCT03740438","title":"Modeling of the Hemoglobin Drop in the Uncomplicated Postoperative Course","phase":"","overall_status":"COMPLETED","enrollment_count":154,"lead_sponsor_name":"Hospital Clinic of Barcelona","has_results":false},{"nct_id":"NCT04508101","title":"Suction Drainage in the Management of Peri-operative Bleeding in Total and Unicomcompartmental Knee Arthroplasty","phase":"","overall_status":"UNKNOWN","enrollment_count":153,"lead_sponsor_name":"I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio","has_results":false},{"nct_id":"NCT05292001","title":"Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Trauma","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Oregon Health and Science University","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}