{"disease":{"id":"arterial-thrombosis","name":"arterial thrombosis"},"drugs":{"marketed":[{"drug_id":"apixaban","indication_name":"Arterial embolus and thrombosis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Eliquis","generic_name":"apixaban","company_name":"Bristol-Myers Squibb","drug_phase":"marketed","molecular_target":"Factor Xa (FXa)","drug_class":"Factor Xa inhibitor","quality_score":85,"revenue":"14443","mechanism":"Apixaban selectively inhibits Factor Xa, decreasing thrombin generation and thrombus development."}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03505723","title":"PeriOperative ISchemic Evaluation-3 Trial","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":9535,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT06727669","title":"Longitudinal Cohort of Thrombosis and Hemostasis Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":3000,"lead_sponsor_name":"Peking University People's Hospital","has_results":false},{"nct_id":"NCT06825416","title":"A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1166,"lead_sponsor_name":"Beijing Suncadia Pharmaceuticals Co., Ltd","has_results":false},{"nct_id":"NCT05411315","title":"Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment","phase":"NA","overall_status":"COMPLETED","enrollment_count":700,"lead_sponsor_name":"Dartmouth-Hitchcock Medical Center","has_results":false},{"nct_id":"NCT04409834","title":"Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":390,"lead_sponsor_name":"The TIMI Study Group","has_results":true},{"nct_id":"NCT05897554","title":"Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)","phase":"NA","overall_status":"COMPLETED","enrollment_count":247,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT06519292","title":"Immune Checkpoint Inhibitor Associated Cardiovascular Adverse Events in Patients With Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":214,"lead_sponsor_name":"Hanneke W. M. van Laarhoven","has_results":false},{"nct_id":"NCT05646394","title":"Registry on Augmented Antithrombotic Treatment Regimens for Patients With Arterial Thrombotic APS","phase":"","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"McMaster University","has_results":false},{"nct_id":"NCT04370691","title":"JETi Lower Extremity Arterial Thrombosis","phase":"","overall_status":"COMPLETED","enrollment_count":129,"lead_sponsor_name":"Abbott Medical Devices","has_results":true},{"nct_id":"NCT04343196","title":"Digital Variance Angiography in Diagnostic Angiographies for Effective Radiation Dose Reduction","phase":"NA","overall_status":"COMPLETED","enrollment_count":114,"lead_sponsor_name":"Kinepict Health Ltd.","has_results":false},{"nct_id":"NCT04367831","title":"Intermediate or Prophylactic-Dose Anticoagulation for Venous or Arterial Thromboembolism in Severe COVID-19","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":94,"lead_sponsor_name":"Columbia University","has_results":true},{"nct_id":"NCT05369767","title":"Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single-dose Injection of SHR-2004 in Healthy Subjects","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":64,"lead_sponsor_name":"Beijing Suncadia Pharmaceuticals Co., Ltd","has_results":false},{"nct_id":"NCT07327788","title":"QL1706 in Combination With Bevacizumab and RALOX HAIC for Hepatocellular Carcinoma With Vp3/4 PVTT","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":38,"lead_sponsor_name":"Nanfang Hospital, Southern Medical University","has_results":false},{"nct_id":"NCT06340763","title":"JETi Hong Kong Post Market Study (PMS)","phase":"","overall_status":"COMPLETED","enrollment_count":12,"lead_sponsor_name":"Abbott Medical Devices","has_results":true}],"total":14},"guidelines":[],"source":"Drug Landscape verified database"}