{"disease":{"id":"acute-respiratory-distress","name":"acute respiratory distress"},"drugs":{"marketed":[{"drug_id":"albumin-human","indication_name":"Acute Respiratory Distress Syndrome (ARDS)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"ALBUMIN HUMAN","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":45,"revenue":null,"mechanism":"Human Albumin 25% contributes to plasma colloid oncotic pressure and transports various substances, stabilizing blood volume."}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06272942","title":"An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States","phase":"","overall_status":"COMPLETED","enrollment_count":640058,"lead_sponsor_name":"Bayer","has_results":false},{"nct_id":"NCT07317817","title":"Research on Risk Assessment and Early Warning Models for Adverse Clinical Outcomes in Critically Ill Patients","phase":"","overall_status":"COMPLETED","enrollment_count":55940,"lead_sponsor_name":"Chongqing Medical University","has_results":false},{"nct_id":"NCT06751693","title":"Development of a Scoring and Prediction Model for Weaning Success in ARDS Patients Using Ventilation Parameters Combined with Artificial Intelligence and Deep Learning Techniques","phase":"","overall_status":"COMPLETED","enrollment_count":25000,"lead_sponsor_name":"Bakirkoy Dr. Sadi Konuk Research and Training Hospital","has_results":false},{"nct_id":"NCT04158479","title":"China Extracorporeal Life Support Registry","phase":"","overall_status":"RECRUITING","enrollment_count":20000,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT04663776","title":"Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform","phase":"","overall_status":"COMPLETED","enrollment_count":16000,"lead_sponsor_name":"Boston Children's Hospital","has_results":false},{"nct_id":"NCT03255109","title":"WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE","phase":"","overall_status":"COMPLETED","enrollment_count":11000,"lead_sponsor_name":"European Society of Intensive Care Medicine","has_results":false},{"nct_id":"NCT04457505","title":"One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19","phase":"","overall_status":"COMPLETED","enrollment_count":8500,"lead_sponsor_name":"Consorcio Centro de Investigación Biomédica en Red (CIBER)","has_results":false},{"nct_id":"NCT05097677","title":"Follow-up of Covid-19 Long Term Sequelae","phase":"","overall_status":"COMPLETED","enrollment_count":7599,"lead_sponsor_name":"Azienda Ospedaliera Universitaria Integrata Verona","has_results":false},{"nct_id":"NCT04663802","title":"Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":7342,"lead_sponsor_name":"University of Pennsylvania","has_results":true},{"nct_id":"NCT05650957","title":"PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia","phase":"","overall_status":"COMPLETED","enrollment_count":7145,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT03415529","title":"Impact of Arterial CO2 Tension on Management and Outcome in Patients With Acute Hypoxemic Respirator Failure and ARDS","phase":"","overall_status":"COMPLETED","enrollment_count":4500,"lead_sponsor_name":"European Society of Intensive Care Medicine","has_results":false},{"nct_id":"NCT05534074","title":"University Hospital of Ioannina COVID-19 (Coronavirus Disease 2019) Registry","phase":"","overall_status":"UNKNOWN","enrollment_count":2500,"lead_sponsor_name":"University Hospital, Ioannina","has_results":false},{"nct_id":"NCT05954351","title":"PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients.","phase":"","overall_status":"COMPLETED","enrollment_count":2465,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT03021824","title":"Severe ARDS: Generating Evidence","phase":"","overall_status":"COMPLETED","enrollment_count":2400,"lead_sponsor_name":"Montefiore Medical Center","has_results":false},{"nct_id":"NCT05162508","title":"Impact of COVID-19 SARS-CoV-2 Variability in ICU Hospitalized Patients With Severe Disease","phase":"","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03260348","title":"Acute Respiratory Distress Syndrome in Taiwan","phase":"","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"Chang Gung Memorial Hospital","has_results":false},{"nct_id":"NCT04319965","title":"Complications Related to Transpulmonary Thermodilution","phase":"","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"Bicetre Hospital","has_results":false},{"nct_id":"NCT06123962","title":"ALI/ARDS Clinical Sub-phenotyping Study","phase":"","overall_status":"RECRUITING","enrollment_count":1500,"lead_sponsor_name":"China-Japan Friendship Hospital","has_results":false},{"nct_id":"NCT04328467","title":"Pre-exposure Prophylaxis for SARS-Coronavirus-2","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1483,"lead_sponsor_name":"University of Minnesota","has_results":true},{"nct_id":"NCT03096314","title":"Vitamin D to Improve Outcomes by Leveraging Early Treatment","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1358,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT04308668","title":"Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1312,"lead_sponsor_name":"University of Minnesota","has_results":true},{"nct_id":"NCT05611177","title":"Predicting ICU Mortality in ARDS Patients","phase":"","overall_status":"COMPLETED","enrollment_count":1303,"lead_sponsor_name":"Dr. Negrin University Hospital","has_results":false},{"nct_id":"NCT05993377","title":"Prediction of Duration of Mechanical Ventilation in ARDS","phase":"","overall_status":"COMPLETED","enrollment_count":1303,"lead_sponsor_name":"Dr. Negrin University Hospital","has_results":false},{"nct_id":"NCT06690801","title":"Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome","phase":"","overall_status":"RECRUITING","enrollment_count":1260,"lead_sponsor_name":"Children's Hospital Los Angeles","has_results":false},{"nct_id":"NCT07369206","title":"ICU Admission Diagnoses and ICU Mortality","phase":"","overall_status":"COMPLETED","enrollment_count":1248,"lead_sponsor_name":"Ataturk University","has_results":false},{"nct_id":"NCT06849570","title":"Assessment of the PEEP Responsiveness to Titrate End-expiratory Pressure and of the Need for Muscle Relaxation During Prone Positioning in Moderate-to-severe Acute Respiratory Distress Syndrome: A Master Protocol","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT07351435","title":"The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1200,"lead_sponsor_name":"University of Genova","has_results":false},{"nct_id":"NCT07086755","title":"Vadadustat for the Treatment of Nonintubated Acute Respiratory Distress Syndrome Due to Pathogen-Associated Lung Injury","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":1100,"lead_sponsor_name":"Bentley J. Bobrow","has_results":false},{"nct_id":"NCT06066502","title":"Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":1100,"lead_sponsor_name":"Beth Israel Deaconess Medical Center","has_results":false},{"nct_id":"NCT05470907","title":"Registry for Hemoperfusion of Covid-19 ICU Patients","phase":"","overall_status":"COMPLETED","enrollment_count":1050,"lead_sponsor_name":"Croatian Society for Organ Support","has_results":false},{"nct_id":"NCT02509078","title":"Reevaluation Of Systemic Early Neuromuscular Blockade","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1008,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT06069466","title":"Epidemiological Characteristics and Prediction System of Acute Respiratory Distress Syndrome","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"China-Japan Friendship Hospital","has_results":false},{"nct_id":"NCT05844579","title":"The ICU LIBERATION Study","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Japanese Society for Early Mobilization","has_results":false},{"nct_id":"NCT07129330","title":"RSPO3/SDC-1 Pathway Dysfunction in Alveolar Repair After ARDS in Older Adults","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","has_results":false},{"nct_id":"NCT05026645","title":"The Medical Management in Patients Exposed to Weapons of Mass Destruction","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1000,"lead_sponsor_name":"St. Justine's Hospital","has_results":false},{"nct_id":"NCT03311165","title":"Epidemiological Study of Neonatal Acute Respiratory Distress Syndrome (ARDS)","phase":"","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"Daping Hospital and the Research Institute of Surgery of the Third Military Medical University","has_results":false},{"nct_id":"NCT06751654","title":"Can Total Mechanical Power Be a Determinant of Weaning Failure in Chronic Obstructive Pulmonary Disease (COPD)?","phase":"","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"Bakirkoy Dr. Sadi Konuk Research and Training Hospital","has_results":false},{"nct_id":"NCT07284888","title":"Practices of Prone Positioning Ventilation in Patients With Moderate-to-Severe ARDS in Intensive Care Units: A Registry-Based Observational Study","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Southeast University, China","has_results":false},{"nct_id":"NCT06598709","title":"International Survey for EXTubation Evaluation and Respiratory Dynamics in Acute Respiratory Distress Syndrome","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1000,"lead_sponsor_name":"Hiroshima University","has_results":false},{"nct_id":"NCT05354141","title":"Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":970,"lead_sponsor_name":"Direct Biologics, LLC","has_results":false},{"nct_id":"NCT04070053","title":"Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway","phase":"NA","overall_status":"COMPLETED","enrollment_count":920,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT04601090","title":"Survival Rates and Longterm Outcomes After COVID-19","phase":"","overall_status":"COMPLETED","enrollment_count":860,"lead_sponsor_name":"Oslo University Hospital","has_results":false},{"nct_id":"NCT03549910","title":"A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDS","phase":"NA","overall_status":"RECRUITING","enrollment_count":840,"lead_sponsor_name":"West China Hospital","has_results":false},{"nct_id":"NCT03089957","title":"Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS)","phase":"NA","overall_status":"COMPLETED","enrollment_count":840,"lead_sponsor_name":"Peking University Third Hospital","has_results":false},{"nct_id":"NCT04896866","title":"Efficacy and Safety of Antimicrobial Stewardship Intervention in Hospitalized COVID-19 Patients (COVASP)","phase":"NA","overall_status":"COMPLETED","enrollment_count":833,"lead_sponsor_name":"University of Alberta","has_results":false},{"nct_id":"NCT07126964","title":"Extended Prone Positioning for Intubated ARDS","phase":"NA","overall_status":"RECRUITING","enrollment_count":800,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT06322758","title":"Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":750,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04068038","title":"Pediatric Acute Respiratory Distress Syndrome Asia Study","phase":"","overall_status":"COMPLETED","enrollment_count":738,"lead_sponsor_name":"KK Women's and Children's Hospital","has_results":false},{"nct_id":"NCT04693403","title":"The Acute Respiratory Intervention StudiEs in Africa (ARISE-AFRICA) Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":705,"lead_sponsor_name":"Makerere University","has_results":false},{"nct_id":"NCT04941209","title":"imPulse™ Una Infrasound-to-ultrasound E-stethoscope","phase":"","overall_status":"COMPLETED","enrollment_count":702,"lead_sponsor_name":"Level 42 AI, Inc.","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}