{"disease":{"id":"acute-hypercapnic-respiratory-failure","name":"acute hypercapnic respiratory failure"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04650412","title":"Integrated Care of Co-morbidities vs Standard Care After AHRF in the Intensive Care Unit","phase":"NA","overall_status":"TERMINATED","enrollment_count":188,"lead_sponsor_name":"CTU","has_results":false},{"nct_id":"NCT06114667","title":"Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":174,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT06495086","title":"HFNC vs. NIV in Acute COPD Exacerbations","phase":"NA","overall_status":"COMPLETED","enrollment_count":137,"lead_sponsor_name":"Haseki Training and Research Hospital","has_results":false},{"nct_id":"NCT04102735","title":"Under the Nose Face Mask to Prevent Facial Pressure Ulcers During NIV for Acute Hypercapnic Respiratory Failure (AHRF)","phase":"NA","overall_status":"COMPLETED","enrollment_count":108,"lead_sponsor_name":"Centre Hospitalier Arras","has_results":false},{"nct_id":"NCT05499039","title":"High Flow Nasal Cannula Versus Non-Invasive (NIV)in Both Hypoxemic and Hypercapnic Respiratory Failure.","phase":"NA","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT05674760","title":"ReAcT CO2: A Study to Assess TcCO2 to Guide Acute NIV","phase":"NA","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Nottingham University Hospitals NHS Trust","has_results":false},{"nct_id":"NCT04362787","title":"High Pressure Non Invasive Ventilation in Hypercapnic Respiratory Failure","phase":"","overall_status":"UNKNOWN","enrollment_count":52,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT04750408","title":"NHF vs. COT in Hypoxemic Pandemic Viral Illness","phase":"NA","overall_status":"UNKNOWN","enrollment_count":52,"lead_sponsor_name":"Jens Bräunlich","has_results":false},{"nct_id":"NCT06374589","title":"Closed-Loop O2 Use During High Flow Oxygen Treatment of Critical Care Adult Patients (CLOUDHFOT)","phase":"NA","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"Başakşehir Çam & Sakura City Hospital","has_results":false},{"nct_id":"NCT06108284","title":"Impact of Negative Pressure Ventilation in Patients Hospitalized With Acute Hypercapnic Respiratory Failure","phase":"NA","overall_status":"TERMINATED","enrollment_count":50,"lead_sponsor_name":"University of Missouri-Columbia","has_results":false},{"nct_id":"NCT05011877","title":"The Simplify Project","phase":"","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"Unity Health Toronto","has_results":false},{"nct_id":"NCT04109560","title":"HFNC and Acute Hypercapnic Respiratory Failure","phase":"","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Argentinian Intensive Care Society","has_results":false},{"nct_id":"NCT06204276","title":"Asymmetrical Versus Conventional High-flow Nasal Cannula in Acute Respiratory Failure","phase":"NA","overall_status":"UNKNOWN","enrollment_count":40,"lead_sponsor_name":"Siriraj Hospital","has_results":false},{"nct_id":"NCT03883555","title":"High Flow Nasal Cannula Therapy for Early Management of Acute Hypercapnic Cardiogenic Pulmonary Edema in the Emergency Department","phase":"","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04568642","title":"Comparing Closed-loop FiO2 Controller With Conventional Control of FiO2","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Dr. Behcet Uz Children's Hospital","has_results":false},{"nct_id":"NCT03033251","title":"High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease","phase":"NA","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Unity Health Toronto","has_results":false},{"nct_id":"NCT03314883","title":"Diaphragmatic Ultrasound in Acute Hypoxic - Hypercapnic Respiratory Failure (ARF)","phase":"NA","overall_status":"COMPLETED","enrollment_count":21,"lead_sponsor_name":"Azienda Ospedaliero Universitaria Maggiore della Carita","has_results":false},{"nct_id":"NCT03756415","title":"CO2 Clearance During Noninvasive Ventilation (NIV)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":20,"lead_sponsor_name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","has_results":false},{"nct_id":"NCT04131660","title":"Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation","phase":"NA","overall_status":"TERMINATED","enrollment_count":14,"lead_sponsor_name":"University Hospital, Rouen","has_results":false}],"total":19},"guidelines":[],"source":"Drug Landscape verified database"}