{"disease":{"id":"abortion","name":"Abortion","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":6},"drugs":{"marketed":[{"drug_id":"progesterone-plus-hcg","indication_name":"Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Progesterone","generic_name":"Progesterone plus HCG","company_name":"Dunamenti REK Istenhegyi IVF Center","drug_phase":"marketed","molecular_target":"progesterone receptor, luteinizing hormone/choriogonadotropin receptor","drug_class":"Progesterone [EPC]","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"progesterone-plus-hcg","indication_name":"Therapeutic abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Progesterone","generic_name":"Progesterone plus HCG","company_name":"Dunamenti REK Istenhegyi IVF Center","drug_phase":"marketed","molecular_target":"progesterone receptor, luteinizing hormone/choriogonadotropin receptor","drug_class":"Progesterone [EPC]","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"ertapenem","indication_name":"Bacteroides Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Invanz","generic_name":"ERTAPENEM","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"","drug_class":"Penem Antibacterial","quality_score":70,"revenue":null,"mechanism":"Invanz works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death."},{"drug_id":"ertapenem","indication_name":"E. Coli Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Invanz","generic_name":"ERTAPENEM","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"","drug_class":"Penem Antibacterial","quality_score":70,"revenue":null,"mechanism":"Invanz works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death."},{"drug_id":"ertapenem","indication_name":"Peptostreptococcus Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Invanz","generic_name":"ERTAPENEM","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"","drug_class":"Penem Antibacterial","quality_score":70,"revenue":null,"mechanism":"Invanz works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death."},{"drug_id":"ertapenem","indication_name":"Prevotella Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Invanz","generic_name":"ERTAPENEM","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"","drug_class":"Penem Antibacterial","quality_score":70,"revenue":null,"mechanism":"Invanz works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death."},{"drug_id":"ertapenem","indication_name":"Septic Abortion due to Porphyromonas","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Invanz","generic_name":"ERTAPENEM","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"","drug_class":"Penem Antibacterial","quality_score":70,"revenue":null,"mechanism":"Invanz works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death."},{"drug_id":"ertapenem","indication_name":"Streptococcal Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Invanz","generic_name":"ERTAPENEM","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"","drug_class":"Penem Antibacterial","quality_score":70,"revenue":null,"mechanism":"Invanz works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death."},{"drug_id":"norfloxacin","indication_name":"Bacteroides Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"E. Coli Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"Enterococcus Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"Gardnerella Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"Peptostreptococcus Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"Prevotella Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"Streptococcal Septic Abortion","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":15,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04360564","title":"RPL: Interval to Live Birth and Adverse Perinatal Outcomes","phase":"","overall_status":"UNKNOWN","enrollment_count":140000,"lead_sponsor_name":"Children's & Women's Health Centre of British Columbia","has_results":false},{"nct_id":"NCT04182503","title":"Environmental Factors and Embryonic Development Project","phase":"","overall_status":"UNKNOWN","enrollment_count":100000,"lead_sponsor_name":"Jinling Hospital, China","has_results":false},{"nct_id":"NCT03220750","title":"University Hospital Advanced Age Pregnant Cohort","phase":"","overall_status":"UNKNOWN","enrollment_count":22000,"lead_sponsor_name":"Peking University","has_results":false},{"nct_id":"NCT06795334","title":"Long Term Impact of Induced Abortion","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":13000,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false},{"nct_id":"NCT04432792","title":"The California Home Abortion by Telehealth (CHAT) Study","phase":"","overall_status":"COMPLETED","enrollment_count":6020,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT03727308","title":"Study of Clinic-based Versus Self-use of Medical Abortion Pills","phase":"","overall_status":"COMPLETED","enrollment_count":4196,"lead_sponsor_name":"Ipas","has_results":false},{"nct_id":"NCT04242212","title":"Study of Clinic-based vs. Self-use of a Misoprostol-only Regimen for Induced Abortion","phase":"","overall_status":"UNKNOWN","enrollment_count":4000,"lead_sponsor_name":"Ipas","has_results":false},{"nct_id":"NCT06787274","title":"Research on Equity in Abortion Care by TeleHealth","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT03413774","title":"Unexplained Early Miscarriage : Role and Prevalence of Lower Genital Tract Infections","phase":"","overall_status":"COMPLETED","enrollment_count":1850,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT03461653","title":"Telemedicin Counselling for Medical Abortion","phase":"NA","overall_status":"COMPLETED","enrollment_count":1598,"lead_sponsor_name":"Karolinska Institutet","has_results":false},{"nct_id":"NCT06002035","title":"Study on Clinical Value of Vitamin D in Recurrent Spontaneous Abortion","phase":"","overall_status":"COMPLETED","enrollment_count":1421,"lead_sponsor_name":"Jianmei Xia","has_results":false},{"nct_id":"NCT03248050","title":"Evaluating an Intervention to Increase Use of Call Centre Support for Self-managed Medical Abortion","phase":"NA","overall_status":"UNKNOWN","enrollment_count":1359,"lead_sponsor_name":"Marie Stopes International","has_results":false},{"nct_id":"NCT03214848","title":"Evaluation of an Intervention to Increase Post-abortion LARC Uptake.","phase":"NA","overall_status":"COMPLETED","enrollment_count":1314,"lead_sponsor_name":"Emory University","has_results":false},{"nct_id":"NCT03622073","title":"Misoprostol Treatment of Mid Trimester Incomplete Abortion by Midwives and Doctors in Uganda.","phase":"NA","overall_status":"COMPLETED","enrollment_count":1191,"lead_sponsor_name":"Makerere University","has_results":false},{"nct_id":"NCT02579785","title":"Using mHealth to Promote Post-Menstrual Regulation Contraceptive Uptake and Continuation in Bangladesh","phase":"NA","overall_status":"COMPLETED","enrollment_count":972,"lead_sponsor_name":"Marie Stopes International","has_results":false},{"nct_id":"NCT04336358","title":"Telemedicine for First Trimester Abortion in South Africa","phase":"NA","overall_status":"UNKNOWN","enrollment_count":900,"lead_sponsor_name":"University of Cape Town","has_results":false},{"nct_id":"NCT06871618","title":"Retrospective Study of Surgical Induced Abortions Between 14 and 16 Weeks of Amenorrhea At Croix Rousse University Hospital in Lyon","phase":"","overall_status":"COMPLETED","enrollment_count":700,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT07422506","title":"A Real-World Study Comparing the Efficacy of Different Treatment Regimens for Early Missed Abortion","phase":"NA","overall_status":"RECRUITING","enrollment_count":580,"lead_sponsor_name":"The Third Xiangya Hospital of Central South University","has_results":false},{"nct_id":"NCT03913104","title":"Mail Order Mifepristone Study","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":536,"lead_sponsor_name":"Daniel Grossman, MD","has_results":true},{"nct_id":"NCT06705712","title":"Physical Activity, Fertility, and Spontaneous Abortion in Danish Couples Trying to Conceive","phase":"NA","overall_status":"RECRUITING","enrollment_count":530,"lead_sponsor_name":"University of Aarhus","has_results":false},{"nct_id":"NCT00878098","title":"Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa","phase":"","overall_status":"COMPLETED","enrollment_count":513,"lead_sponsor_name":"National Institute of Environmental Health Sciences (NIEHS)","has_results":false},{"nct_id":"NCT05516810","title":"The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":500,"lead_sponsor_name":"King's College Hospital NHS Trust","has_results":false},{"nct_id":"NCT05169541","title":"Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Aalborg University Hospital","has_results":false},{"nct_id":"NCT05481606","title":"Cesarean Scar Pregnancy and Clinical Outcomes","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Peking University Third Hospital","has_results":false},{"nct_id":"NCT05725512","title":"Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":490,"lead_sponsor_name":"Leiden University Medical Center","has_results":false},{"nct_id":"NCT04017754","title":"Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)","phase":"","overall_status":"COMPLETED","enrollment_count":452,"lead_sponsor_name":"Aalborg University Hospital","has_results":true},{"nct_id":"NCT03227614","title":"Friends/Family in the Abortion Procedure Room (FAIR)","phase":"NA","overall_status":"COMPLETED","enrollment_count":422,"lead_sponsor_name":"Planned Parenthood of Southwest and Central Florida","has_results":false},{"nct_id":"NCT07405294","title":"TeleMAb Retrospective Cohort Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Columbia University","has_results":false},{"nct_id":"NCT05182008","title":"A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":365,"lead_sponsor_name":"Nova Scotia Health Authority","has_results":false},{"nct_id":"NCT05532085","title":"Assessment of Pain During an Abortion With Knowledge of the Predictive Factors of Pain.","phase":"","overall_status":"COMPLETED","enrollment_count":362,"lead_sponsor_name":"Olivier CHASSANY","has_results":false},{"nct_id":"NCT06894732","title":"To Study the Safety and Efficacy of Disposable Cyclone Ring in Artificial Abortion","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":332,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false},{"nct_id":"NCT03320057","title":"Medication Abortion Via Pharmacy Dispensing","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":326,"lead_sponsor_name":"Daniel Grossman","has_results":true},{"nct_id":"NCT04593108","title":"Misoprostol With or Without Letrozole in Treatment of Missed Miscarriage","phase":"","overall_status":"UNKNOWN","enrollment_count":320,"lead_sponsor_name":"Dr.Dalia Mohammed Al Sayed Zaki","has_results":false},{"nct_id":"NCT03659045","title":"Pain Assessment in MToP Up to 7 WA (during 5h After Misoprostol Intake)","phase":"NA","overall_status":"COMPLETED","enrollment_count":320,"lead_sponsor_name":"Assistance Publique Hopitaux De Marseille","has_results":false},{"nct_id":"NCT04290832","title":"Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa","phase":"NA","overall_status":"TERMINATED","enrollment_count":317,"lead_sponsor_name":"Ipas","has_results":false},{"nct_id":"NCT06435949","title":"Effect of Oxycodone on Anxiety State in Painless Abortion","phase":"EARLY_PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":300,"lead_sponsor_name":"Ruijin Hospital","has_results":false},{"nct_id":"NCT03165136","title":"Hydroxychloroquine for Prevention of Recurrent Miscarriage.","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"University Hospital, Brest","has_results":false},{"nct_id":"NCT04326595","title":"Histopathological Evaluation of Product of Conception in Sporadic and Recurrent Abortions","phase":"NA","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT05001061","title":"Sublingual vs Vaginal Misoprostol for Termination of First Trimesteric Missed Abortion","phase":"EARLY_PHASE1","overall_status":"UNKNOWN","enrollment_count":288,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT06081556","title":"Difference Between Mean Gestational Sac Diameter and Crown-rump Length as a Marker of First-trimester Pregnancy Outcome in Patients With Recurrent Spontaneous Abortion","phase":"","overall_status":"COMPLETED","enrollment_count":256,"lead_sponsor_name":"The First Affiliated Hospital of Xiamen University","has_results":false},{"nct_id":"NCT04181541","title":"Midlevel Versus Physician-provided Medical Abortion in the Second Trimester","phase":"NA","overall_status":"COMPLETED","enrollment_count":245,"lead_sponsor_name":"Ipas","has_results":false},{"nct_id":"NCT02846909","title":"The Vaginal Progesterone and Cerclage","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":242,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT05986357","title":"The Relation of High Sensitivity C Reactive Protein and Total Leucocytic Count Levels in Threatened Abortion","phase":"","overall_status":"UNKNOWN","enrollment_count":240,"lead_sponsor_name":"Beni-Suef University","has_results":false},{"nct_id":"NCT04499976","title":"Isonicotinic Acid Hydrazide Pretreatment With Misoprostol Induction of Abortion in First-trimester Missed Miscarriage","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":240,"lead_sponsor_name":"Aswan University Hospital","has_results":false},{"nct_id":"NCT03346629","title":"Outpatient Service for Mid-trimester Termination of Pregnancy","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":230,"lead_sponsor_name":"Gynuity Health Projects","has_results":false},{"nct_id":"NCT04181021","title":"Evaluation of Values Clarification and Attitude Transformation Workshops on Abortion and Family Planning Service Provision and Client Experience","phase":"NA","overall_status":"COMPLETED","enrollment_count":217,"lead_sponsor_name":"Ibis Reproductive Health","has_results":false},{"nct_id":"NCT05688228","title":"Voluntary Interruption of Pregnancy on Women's Sexuality","phase":"","overall_status":"COMPLETED","enrollment_count":209,"lead_sponsor_name":"University Hospital, Bordeaux","has_results":false},{"nct_id":"NCT02309346","title":"Clindamycin Once a Day in Septic Abortion","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":202,"lead_sponsor_name":"Hospital de Clinicas de Porto Alegre","has_results":true},{"nct_id":"NCT05413525","title":"Ultrasound-guided Manual Vacuum Aspiration (USG-MVA)","phase":"","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Chinese University of Hong Kong","has_results":false},{"nct_id":"NCT06999278","title":"LIGHT Trial: Levothyroxine for Gestational Hypothyroidism in Recurrent Pregnancy Loss","phase":"PHASE3","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Women's Hospital School Of Medicine Zhejiang University","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}