{"name":"Organon and Co","slug":"organon-and-co","ticker":"","exchange":"","domain":"organonand.com","description":"","hq":"","founded":0,"employees":"","ceo":"","sector":"Pharma / Biotech","stockPrice":0,"stockChange":0,"stockChangePercent":0,"marketCap":"","metrics":{"revenue":0,"revenueGrowth":0,"grossMargin":0,"rdSpend":0,"netIncome":0,"cash":0,"dividendYield":0,"peRatio":0,"fiscalYear":"FY2026"},"revenueBreakdown":[],"timeline":[{"date":"2026-07-28","label":"Q2 2026 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2026-10-28","label":"Q3 2026 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-01-28","label":"Q4 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-04-28","label":"Q1 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-07-28","label":"Q2 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-10-28","label":"Q3 2027 Earnings","type":"earnings","sentiment":"neutral"}],"diseaseAreas":[{"name":"Other","slug":"other","revenue":0,"percentOfTotal":0,"drugCount":66,"colorKey":"neuroscience","drugs":[{"name":"Comparator: Usual Care","genericName":"Comparator: Usual Care","slug":"comparator-usual-care","indication":"Other","status":"phase_3"},{"name":"Etoricoxib 90 mg","genericName":"Etoricoxib 90 mg","slug":"etoricoxib-90-mg","indication":"Other","status":"marketed"},{"name":"Hypolipemics","genericName":"Hypolipemics","slug":"hypolipemics","indication":"Other","status":"phase_2"},{"name":"MK0217, /Duration of Treatment : 12 Months","genericName":"MK0217, /Duration of Treatment : 12 Months","slug":"mk0217-duration-of-treatment-12-months","indication":"Other","status":"phase_3"},{"name":"Rizatriptan 10 mg","genericName":"Rizatriptan 10 mg","slug":"rizatriptan-10-mg","indication":"Other","status":"phase_3"},{"name":"etorocoxib","genericName":"etorocoxib","slug":"etorocoxib","indication":"Other","status":"phase_2"},{"name":"fluticasone propionate hydrofluoroalkane (HFA)","genericName":"fluticasone propionate hydrofluoroalkane (HFA)","slug":"fluticasone-propionate-hydrofluoroalkane-hfa","indication":"Other","status":"marketed"},{"name":"(rec)hCG","genericName":"(rec)hCG","slug":"rec-hcg","indication":"Induction of ovulation in anovulatory women","status":"phase_3"},{"name":"20-mg Desloratadine","genericName":"20-mg Desloratadine","slug":"20-mg-desloratadine","indication":"Other","status":"marketed"},{"name":"Asenapine - Open Label","genericName":"Asenapine - Open Label","slug":"asenapine-open-label","indication":"Other","status":"phase_3"},{"name":"Asmanex twisthaler","genericName":"Asmanex twisthaler","slug":"asmanex-twisthaler","indication":"Other","status":"marketed"},{"name":"Atorvastatin 10 mg","genericName":"Atorvastatin 10 mg","slug":"atorvastatin-10-mg","indication":"Other","status":"marketed"},{"name":"Atorvastatin 80 mg","genericName":"Atorvastatin 80 mg","slug":"atorvastatin-80-mg","indication":"Other","status":"marketed"},{"name":"Atovastatin","genericName":"Atovastatin","slug":"atovastatin","indication":"Other","status":"phase_3"},{"name":"Beclomethasone dipropionate nasal spray","genericName":"Beclomethasone dipropionate nasal spray","slug":"beclomethasone-dipropionate-nasal-spray","indication":"Allergic rhinitis","status":"phase_3"},{"name":"CE/MPA","genericName":"CE/MPA","slug":"ce-mpa","indication":"Contraception","status":"phase_3"},{"name":"Chlorpheniramine maleate syrup","genericName":"Chlorpheniramine maleate syrup","slug":"chlorpheniramine-maleate-syrup","indication":"Allergic rhinitis","status":"phase_3"},{"name":"Comparator: cetirizine","genericName":"Comparator: cetirizine","slug":"comparator-cetirizine","indication":"Allergic rhinitis (seasonal and perennial)","status":"phase_3"},{"name":"Comparator: loratadine","genericName":"Comparator: loratadine","slug":"comparator-loratadine","indication":"Allergic rhinitis (seasonal and perennial)","status":"phase_3"},{"name":"Desloratadine (Clarinex)","genericName":"Desloratadine (Clarinex)","slug":"desloratadine-clarinex","indication":"Allergic rhinitis (seasonal and perennial)","status":"phase_3"},{"name":"Desloratadine 5 mg","genericName":"Desloratadine 5 mg","slug":"desloratadine-5-mg","indication":"Other","status":"marketed"},{"name":"Desloratadine placebo tablet","genericName":"Desloratadine placebo tablet","slug":"desloratadine-placebo-tablet","indication":"Clinical trial control (not a therapeutic indication)","status":"marketed"},{"name":"Duration of Treatment: 3 months","genericName":"Duration of Treatment: 3 months","slug":"duration-of-treatment-3-months","indication":"Treatment of endometriosis","status":"phase_3"},{"name":"Duration of Treatment: 6 weeks","genericName":"Duration of Treatment: 6 weeks","slug":"duration-of-treatment-6-weeks","indication":"Treatment of endometriosis","status":"phase_3"},{"name":"E6005","genericName":"E6005","slug":"e6005","indication":"Other","status":"phase_2"},{"name":"ENG 120 µg + EE 15 µg intravaginal ring","genericName":"ENG 120 µg + EE 15 µg intravaginal ring","slug":"eng-120-g-ee-15-g-intravaginal-ring","indication":"Contraception in women of reproductive age","status":"phase_3"},{"name":"Etidronate","genericName":"Etidronate","slug":"etidronate","indication":"Heterotopic ossification","status":"phase_3"},{"name":"Etonogestrel-releasing IUS","genericName":"Etonogestrel-releasing IUS","slug":"etonogestrel-releasing-ius","indication":"Contraception for up to 5 years","status":"phase_2"},{"name":"FOSAMAX PLUS","genericName":"FOSAMAX PLUS","slug":"fosamax-plus","indication":"Osteoporosis in postmenopausal women","status":"marketed"},{"name":"FOSAMAX PLUS D","genericName":"FOSAMAX PLUS D","slug":"fosamax-plus-d","indication":"Osteoporosis prevention and treatment in postmenopausal women","status":"marketed"},{"name":"Follitropin beta injection","genericName":"Follitropin beta injection","slug":"follitropin-beta-injection","indication":"Induction of ovulation in anovulatory infertile women, Assisted reproductive technology","status":"phase_2"},{"name":"INEGY","genericName":"INEGY","slug":"inegy","indication":"Hormone replacement therapy","status":"phase_2"},{"name":"LNG-EE","genericName":"LNG-EE","slug":"lng-ee","indication":"Contraception / prevention of pregnancy","status":"phase_3"},{"name":"MK-0954A","genericName":"MK-0954A","slug":"mk-0954a","indication":"Chemotherapy-induced nausea and vomiting (CINV)","status":"phase_3"},{"name":"MK0733 / Duration of Treatment: 18 Weeks","genericName":"MK0733 / Duration of Treatment: 18 Weeks","slug":"mk0733-duration-of-treatment-18-weeks","indication":"Chemotherapy-induced nausea and vomiting (CINV)","status":"phase_3"},{"name":"MK0954, /Duration of Treatment : 5 Years","genericName":"MK0954, /Duration of Treatment : 5 Years","slug":"mk0954-duration-of-treatment-5-years","indication":"Chemotherapy-induced nausea and vomiting (CINV)","status":"phase_3"},{"name":"Matching Placebo for Ibuprofen","genericName":"Matching Placebo for Ibuprofen","slug":"matching-placebo-for-ibuprofen","indication":"Control arm in phase 3 clinical trials for ibuprofen efficacy and safety","status":"phase_3"},{"name":"Matching placebo nasal spray","genericName":"Matching placebo nasal spray","slug":"matching-placebo-nasal-spray","indication":"Other","status":"phase_3"},{"name":"Mometasone Furoate MDI 200 mcg","genericName":"Mometasone Furoate MDI 200 mcg","slug":"mometasone-furoate-mdi-200-mcg","indication":"Other","status":"marketed"},{"name":"Mometasone furoate dry powder inhaler","genericName":"Mometasone furoate dry powder inhaler","slug":"mometasone-furoate-dry-powder-inhaler","indication":"Other","status":"marketed"},{"name":"Montelukast chewable tablets","genericName":"Montelukast chewable tablets","slug":"montelukast-chewable-tablets","indication":"Other","status":"marketed"},{"name":"Phase 3 NOMAC-E2 \"Batch A\"","genericName":"Phase 3 NOMAC-E2 \"Batch A\"","slug":"phase-3-nomac-e2-batch-a","indication":"Contraception in women of reproductive age","status":"marketed"},{"name":"Placebo Corifollitropin alfa","genericName":"Placebo Corifollitropin alfa","slug":"placebo-corifollitropin-alfa","indication":"Controlled ovarian hyperstimulation in women undergoing assisted reproductive technology (ART) for infertility","status":"phase_3"},{"name":"Placebo for FDC EZ/Ator","genericName":"Placebo for FDC EZ/Ator","slug":"placebo-for-fdc-ez-ator","indication":"FDC EZ/Ator treatment for phase 3 clinical trials","status":"phase_3"},{"name":"Placebo for FP","genericName":"Placebo for FP","slug":"placebo-for-fp","indication":"FP (indication not specified)","status":"phase_3"},{"name":"Placebo for MF","genericName":"Placebo for MF","slug":"placebo-for-mf","indication":"Other","status":"phase_3"},{"name":"Placebo for MFNS","genericName":"Placebo for MFNS","slug":"placebo-for-mfns","indication":"Mild to moderate menopausal flushing","status":"phase_3"},{"name":"Placebo for SCH 900962","genericName":"Placebo for SCH 900962","slug":"placebo-for-sch-900962","indication":"Other","status":"phase_3"},{"name":"Placebo for etoricoxib","genericName":"Placebo for etoricoxib","slug":"placebo-for-etoricoxib","indication":"Control arm in clinical trials for etoricoxib efficacy evaluation","status":"marketed"},{"name":"Placebo for recFSH","genericName":"Placebo for recFSH","slug":"placebo-for-recfsh","indication":"Control arm in clinical trials for recombinant FSH in female infertility / assisted reproductive technology","status":"phase_3"},{"name":"Placebo to MK-0954A","genericName":"Placebo to MK-0954A","slug":"placebo-to-mk-0954a","indication":"Chemotherapy-induced nausea and vomiting (CINV)","status":"phase_3"},{"name":"Placebo to MK-954H","genericName":"Placebo to MK-954H","slug":"placebo-to-mk-954h","indication":"Other","status":"phase_3"},{"name":"Placebo to match amlodipine","genericName":"Placebo to match amlodipine","slug":"placebo-to-match-amlodipine","indication":"Use as control in clinical trials comparing amlodipine efficacy and safety","status":"marketed"},{"name":"Placebo to match asenapine","genericName":"Placebo to match asenapine","slug":"placebo-to-match-asenapine","indication":"Control comparator in phase 3 clinical trials of asenapine","status":"phase_3"},{"name":"Placebo vaginal ring","genericName":"Placebo vaginal ring","slug":"placebo-vaginal-ring","indication":"Placebo control in clinical trials for vaginal ring contraceptives and hormone replacement therapies","status":"marketed"},{"name":"Radiopaque Etonogestrel Implant","genericName":"Radiopaque Etonogestrel Implant","slug":"radiopaque-etonogestrel-implant","indication":"Contraception in women of reproductive age","status":"phase_3"},{"name":"Radiopaque Implanon","genericName":"Radiopaque Implanon","slug":"radiopaque-implanon","indication":"Long-acting reversible contraception in women of reproductive age","status":"phase_3"},{"name":"Simivastatin","genericName":"Simivastatin","slug":"simivastatin","indication":"Other","status":"phase_3"},{"name":"aminophylline hydrate","genericName":"aminophylline hydrate","slug":"aminophylline-hydrate","indication":"Other","status":"phase_3"},{"name":"estradiol-norethisterone","genericName":"estradiol-norethisterone","slug":"estradiol-norethisterone","indication":"Treatment of moderate to severe vasomotor symptoms associated with menopause","status":"phase_3"},{"name":"fluticasone nasal spray","genericName":"fluticasone nasal spray","slug":"fluticasone-nasal-spray","indication":"Other","status":"marketed"},{"name":"low-dose estradiol/noresterone","genericName":"low-dose estradiol/noresterone","slug":"low-dose-estradiol-noresterone","indication":"Contraception","status":"marketed"},{"name":"mometasone furoate nasal spray","genericName":"mometasone furoate nasal spray","slug":"mometasone-furoate-nasal-spray","indication":"Other","status":"marketed"},{"name":"open-label recFSH","genericName":"open-label recFSH","slug":"open-label-recfsh","indication":"Treatment of infertility in women","status":"phase_3"},{"name":"placebo nasal spray","genericName":"placebo nasal spray","slug":"placebo-nasal-spray","indication":"Other","status":"marketed"},{"name":"recFSH","genericName":"recFSH","slug":"recfsh","indication":"Other","status":"marketed"}]},{"name":"Cardiovascular","slug":"cardiovascular","revenue":0,"percentOfTotal":0,"drugCount":21,"colorKey":"immunology","drugs":[{"name":"A-Phase: tirofiban; Z-Phase simvastatin","genericName":"A-Phase: tirofiban; Z-Phase simvastatin","slug":"a-phase-tirofiban-z-phase-simvastatin","indication":"Acute coronary syndrome (unstable angina and non-ST elevation myocardial infarction)","status":"phase_3"},{"name":"Comparator: simvastatin","genericName":"Comparator: simvastatin","slug":"comparator-simvastatin","indication":"Hypercholesterolemia","status":"phase_3"},{"name":"MK0733, simvastatin","genericName":"MK0733, simvastatin","slug":"mk0733-simvastatin","indication":"Hypercholesterolemia and dyslipidemia","status":"phase_3"},{"name":"ezetimibe/simvastatin 10/40","genericName":"ezetimibe/simvastatin 10/40","slug":"ezetimibe-simvastatin-10-40","indication":"Hypercholesterolemia and mixed dyslipidemia","status":"phase_3"},{"name":"Amlodipine camsylate","genericName":"Amlodipine camsylate","slug":"amlodipine-camsylate","indication":"Hypertension","status":"marketed"},{"name":"Comparator: amlodipine besylate","genericName":"Comparator: amlodipine besylate","slug":"comparator-amlodipine-besylate","indication":"Hypertension","status":"phase_3"},{"name":"Comparator: atorvastatin","genericName":"Comparator: atorvastatin","slug":"comparator-atorvastatin","indication":"Hypercholesterolemia and dyslipidemia","status":"marketed"},{"name":"Comparator: carvedilol","genericName":"Comparator: carvedilol","slug":"comparator-carvedilol","indication":"Hypertension","status":"marketed"},{"name":"Comparator: fluvastatin","genericName":"Comparator: fluvastatin","slug":"comparator-fluvastatin","indication":"Hypercholesterolemia and dyslipidemia for reduction of cardiovascular risk","status":"phase_3"},{"name":"Comparator: losartan +/- HCTZ","genericName":"Comparator: losartan +/- HCTZ","slug":"comparator-losartan-hctz","indication":"Hypertension (as combination therapy or monotherapy with losartan)","status":"phase_3"},{"name":"Comparator: lovastatin","genericName":"Comparator: lovastatin","slug":"comparator-lovastatin","indication":"Hypercholesterolemia","status":"phase_3"},{"name":"Comparator: placebo, losartan, hydrochlorothiazide","genericName":"Comparator: placebo, losartan, hydrochlorothiazide","slug":"comparator-placebo-losartan-hydrochlorothiazide","indication":"Hypertension","status":"phase_3"},{"name":"Comparator: pravastatin","genericName":"Comparator: pravastatin","slug":"comparator-pravastatin","indication":"Hypercholesterolemia","status":"phase_3"},{"name":"Comparator: statins","genericName":"Comparator: statins","slug":"comparator-statins","indication":"Hypercholesterolemia and dyslipidemia","status":"phase_3"},{"name":"Comparators: simvastatin and ezetimibe","genericName":"Comparators: simvastatin and ezetimibe","slug":"comparators-simvastatin-and-ezetimibe","indication":"Hypercholesterolemia / dyslipidemia for cardiovascular risk reduction","status":"phase_3"},{"name":"Double Atorvastatin","genericName":"Double Atorvastatin","slug":"double-atorvastatin","indication":"Hypercholesterolemia and dyslipidemia","status":"marketed"},{"name":"Eptifibatide (Integrilin)","genericName":"Eptifibatide (Integrilin)","slug":"eptifibatide-integrilin","indication":"Acute coronary syndrome (unstable angina and non-ST elevation myocardial infarction)","status":"phase_3"},{"name":"Ezetimibe + Atorvastatin","genericName":"Ezetimibe + Atorvastatin","slug":"ezetimibe-atorvastatin","indication":"Hypercholesterolemia and mixed dyslipidemia","status":"marketed"},{"name":"Ezetimibe + Simvastatin","genericName":"Ezetimibe + Simvastatin","slug":"ezetimibe-simvastatin","indication":"Hypercholesterolemia and mixed dyslipidemia","status":"marketed"},{"name":"Losartan (+) amlodipine","genericName":"Losartan (+) amlodipine","slug":"losartan-amlodipine","indication":"Hypertension","status":"marketed"},{"name":"Other Statin","genericName":"Other Statin","slug":"other-statin","indication":"Hypercholesterolemia","status":"marketed"}]},{"name":"Respiratory","slug":"respiratory","revenue":0,"percentOfTotal":0,"drugCount":13,"colorKey":"rare","drugs":[{"name":"Albuterol/Salbutamol PRN","genericName":"Albuterol/Salbutamol PRN","slug":"albuterol-salbutamol-prn","indication":"Acute bronchospasm relief in asthma","status":"phase_3"},{"name":"Budesonide DPI","genericName":"Budesonide DPI","slug":"budesonide-dpi","indication":"Asthma (maintenance and reliever therapy)","status":"phase_3"},{"name":"Comparator: Montelukast","genericName":"Comparator: Montelukast","slug":"comparator-montelukast","indication":"Asthma (maintenance and acute prevention)","status":"marketed"},{"name":"Comparator: Salmeterol","genericName":"Comparator: Salmeterol","slug":"comparator-salmeterol","indication":"Asthma maintenance therapy","status":"phase_3"},{"name":"Comparator: montelukast/loratadine","genericName":"Comparator: montelukast/loratadine","slug":"comparator-montelukast-loratadine","indication":"Allergic rhinitis and asthma (combination indication)","status":"phase_3"},{"name":"Comparator: pranlukast","genericName":"Comparator: pranlukast","slug":"comparator-pranlukast","indication":"Asthma (allergic and exercise-induced)","status":"phase_3"},{"name":"Formoterol MDI","genericName":"Formoterol MDI","slug":"formoterol-mdi","indication":"Asthma maintenance therapy","status":"phase_3"},{"name":"Loratadine/montelukast combination","genericName":"Loratadine/montelukast combination","slug":"loratadine-montelukast-combination","indication":"Allergic rhinitis","status":"phase_3"},{"name":"MK0476; montelukast sodium","genericName":"MK0476; montelukast sodium","slug":"mk0476-montelukast-sodium","indication":"Asthma (maintenance and prophylaxis)","status":"marketed"},{"name":"Montelukast Oral Granules (OG)","genericName":"Montelukast Oral Granules (OG)","slug":"montelukast-oral-granules-og","indication":"Asthma (prophylaxis and chronic treatment)","status":"phase_3"},{"name":"Placebo to budesonide inhaler","genericName":"Placebo to budesonide inhaler","slug":"placebo-to-budesonide-inhaler","indication":"Asthma maintenance therapy","status":"marketed"},{"name":"Placebo to montelukast chewable tablets","genericName":"Placebo to montelukast chewable tablets","slug":"placebo-to-montelukast-chewable-tablets","indication":"Asthma (prophylaxis and chronic treatment)","status":"marketed"},{"name":"loratadine; montelukast","genericName":"loratadine; montelukast","slug":"loratadine-montelukast","indication":"Perennial allergic rhinitis","status":"phase_3"}]},{"name":"Immunology","slug":"immunology","revenue":0,"percentOfTotal":0,"drugCount":9,"colorKey":"ophthalmology","drugs":[{"name":"Comparator: Diclofenac sodium","genericName":"Comparator: Diclofenac sodium","slug":"comparator-diclofenac-sodium","indication":"Acute pain and inflammation","status":"phase_3"},{"name":"Comparator: celecoxib","genericName":"Comparator: celecoxib","slug":"comparator-celecoxib","indication":"Rheumatoid arthritis","status":"phase_3"},{"name":"Comparator: etoricoxib","genericName":"Comparator: etoricoxib","slug":"comparator-etoricoxib","indication":"Rheumatoid arthritis","status":"phase_3"},{"name":"Comparator: ibuprofen","genericName":"Comparator: ibuprofen","slug":"comparator-ibuprofen","indication":"Mild to moderate pain","status":"phase_3"},{"name":"Comparator: naproxen sodium","genericName":"Comparator: naproxen sodium","slug":"comparator-naproxen-sodium","indication":"Mild to moderate pain","status":"phase_3"},{"name":"Duration of Treatment: Z-Phase, 2 years.","genericName":"Duration of Treatment: Z-Phase, 2 years.","slug":"duration-of-treatment-z-phase-2-years","indication":"Moderate to severe rheumatoid arthritis","status":"phase_3"},{"name":"MK0663, etoricoxib","genericName":"MK0663, etoricoxib","slug":"mk0663-etoricoxib","indication":"Osteoarthritis","status":"phase_3"},{"name":"Placebo to etoricoxib","genericName":"Placebo to etoricoxib","slug":"placebo-to-etoricoxib","indication":"Osteoarthritis","status":"phase_3"},{"name":"Placebo to ibuprofen","genericName":"Placebo to ibuprofen","slug":"placebo-to-ibuprofen","indication":"Relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, and other conditions","status":"phase_3"}]},{"name":"Metabolic","slug":"metabolic","revenue":0,"percentOfTotal":0,"drugCount":7,"colorKey":"respiratory","drugs":[{"name":"Comparator: ezetimibe and simvastatin","genericName":"Comparator: ezetimibe and simvastatin","slug":"comparator-ezetimibe-and-simvastatin","indication":"Hypercholesterolemia and mixed dyslipidemia","status":"phase_3"},{"name":"MK-0653, ezetimibe","genericName":"MK-0653, ezetimibe","slug":"mk-0653-ezetimibe","indication":"Hyperlipidemia","status":"phase_3"},{"name":"MK0653, 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disorders","status":"phase_3"},{"name":"MK-954H","genericName":"MK-954H","slug":"mk-954h","indication":"Non-small cell lung cancer, PD-L1 positive","status":"phase_3"},{"name":"Prednisone/Prednisolone","genericName":"Prednisone/Prednisolone","slug":"prednisone-prednisolone","indication":"Rheumatoid arthritis and other autoimmune inflammatory conditions","status":"marketed"}]},{"name":"Dermatology","slug":"dermatology","revenue":0,"percentOfTotal":0,"drugCount":5,"colorKey":"metabolic","drugs":[{"name":"Cetirizine (Zyrtec)","genericName":"Cetirizine (Zyrtec)","slug":"cetirizine-zyrtec","indication":"Allergic rhinitis (seasonal and perennial)","status":"marketed"},{"name":"DRSP-EE","genericName":"DRSP-EE","slug":"drsp-ee","indication":"Contraception (prevention of pregnancy)","status":"phase_3"},{"name":"Mometasone Furoate (MF)","genericName":"Mometasone Furoate (MF)","slug":"mometasone-furoate-mf","indication":"Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses","status":"phase_3"},{"name":"VTAMA (tapinarof) cream, 1%","genericName":"VTAMA (tapinarof) cream, 1%","slug":"vtama-tapinarof-cream-1","indication":"Atopic dermatitis (mild to moderate)","status":"marketed"},{"name":"Vehicle Cream","genericName":"Vehicle Cream","slug":"vehicle-cream","indication":"Pharmaceutical vehicle/excipient for topical dermatological formulations","status":"marketed"}]},{"name":"Pain","slug":"pain","revenue":0,"percentOfTotal":0,"drugCount":2,"colorKey":"infectious","drugs":[{"name":"Comparator: acetaminophen + codeine","genericName":"Comparator: acetaminophen + codeine","slug":"comparator-acetaminophen-codeine","indication":"Moderate pain","status":"phase_3"},{"name":"MK0954, /Duration of Treatment : 16 Weeks","genericName":"MK0954, /Duration of Treatment : 16 Weeks","slug":"mk0954-duration-of-treatment-16-weeks","indication":"Chronic pain conditions (Phase 3 development)","status":"phase_3"}]},{"name":"Infectious Disease","slug":"infectious-disease","revenue":0,"percentOfTotal":0,"drugCount":1,"colorKey":"dermatology","drugs":[{"name":"Zyrtec® (cetirizine)","genericName":"Zyrtec® (cetirizine)","slug":"zyrtec-cetirizine","indication":"Seasonal and perennial allergic rhinitis","status":"marketed"}]}],"pipeline":[{"name":"raloxifen","genericName":"raloxifen","slug":"raloxifen","phase":"marketed","mechanism":"Aldehyde oxidase, HLA class I histocompatibility antigen, A-3 alpha chain, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase","indications":["Postmenopausal osteoporosis","Prevention of Breast Carcinoma"],"catalyst":""},{"name":"A-Phase: tirofiban; Z-Phase simvastatin","genericName":"A-Phase: tirofiban; Z-Phase simvastatin","slug":"a-phase-tirofiban-z-phase-simvastatin","phase":"phase_3","mechanism":"This is a combination therapy pairing tirofiban (a platelet glycoprotein IIb/IIIa inhibitor) with simvastatin (an HMG-CoA reductase inhibitor/statin) to provide dual antiplatelet and lipid-lowering effects.","indications":["Acute coronary syndrome (unstable angina and non-ST elevation myocardial infarction)","Secondary prevention of cardiovascular events in patients with hyperlipidemia"],"catalyst":""},{"name":"Comparator: Rizatriptan","genericName":"Comparator: Rizatriptan","slug":"comparator-rizatriptan","phase":"phase_3","mechanism":"Rizatriptan is a selective serotonin 5-HT1B/1D receptor agonist that constricts cranial blood vessels and inhibits neuropeptide release to relieve migraine headaches.","indications":["Acute treatment of migraine with or without aura in adults"],"catalyst":""},{"name":"Comparator: Usual Care","genericName":"Comparator: Usual Care","slug":"comparator-usual-care","phase":"phase_3","mechanism":"Usual Care is a comparator arm representing standard clinical management without the investigational intervention.","indications":[],"catalyst":""},{"name":"Comparator: acetaminophen + codeine","genericName":"Comparator: acetaminophen + codeine","slug":"comparator-acetaminophen-codeine","phase":"phase_3","mechanism":"Acetaminophen reduces fever and pain through central nervous system effects, while codeine is an opioid agonist that enhances analgesia and suppresses cough.","indications":["Moderate pain","Pain with fever"],"catalyst":""},{"name":"Comparator: ezetimibe and simvastatin","genericName":"Comparator: ezetimibe and simvastatin","slug":"comparator-ezetimibe-and-simvastatin","phase":"phase_3","mechanism":"This is a fixed-dose combination of ezetimibe (which blocks cholesterol absorption in the intestine) and simvastatin (which inhibits HMG-CoA reductase to reduce cholesterol synthesis), working synergistically to lower LDL cholesterol.","indications":["Hypercholesterolemia and mixed dyslipidemia"],"catalyst":""},{"name":"Comparator: simvastatin","genericName":"Comparator: simvastatin","slug":"comparator-simvastatin","phase":"phase_3","mechanism":"Simvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia","Primary prevention of cardiovascular disease","Secondary prevention of cardiovascular events in patients with established coronary heart disease"],"catalyst":""},{"name":"Comparator: sumatriptan","genericName":"Comparator: sumatriptan","slug":"comparator-sumatriptan","phase":"phase_3","mechanism":"Sumatriptan is a selective serotonin 5-HT1B/1D receptor agonist that constricts cranial blood vessels and inhibits neuropeptide release to relieve migraine headaches.","indications":["Acute migraine with or without aura","Cluster headache"],"catalyst":""},{"name":"Etoricoxib 90 mg","genericName":"Etoricoxib 90 mg","slug":"etoricoxib-90-mg","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Hypolipemics","genericName":"Hypolipemics","slug":"hypolipemics","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"MFNS","genericName":"MFNS","slug":"mfns","phase":"phase_3","mechanism":"MFNS is a progestin (megestrol acetate formulation) that acts as a synthetic progesterone receptor agonist to suppress appetite and promote weight gain in cachectic patients.","indications":["Cancer cachexia and anorexia","Weight loss and appetite stimulation in advanced malignancy"],"catalyst":""},{"name":"MK-0653, ezetimibe","genericName":"MK-0653, ezetimibe","slug":"mk-0653-ezetimibe","phase":"phase_3","mechanism":"Ezetimibe inhibits the absorption of cholesterol in the small intestine.","indications":["Hyperlipidemia","Homozygous familial hypercholesterolemia"],"catalyst":""},{"name":"MK0217, /Duration of Treatment : 12 Months","genericName":"MK0217, /Duration of Treatment : 12 Months","slug":"mk0217-duration-of-treatment-12-months","phase":"phase_3","mechanism":"MK0217 is an investigational compound developed by Organon that modulates a specific molecular target to treat its indicated condition.","indications":[],"catalyst":""},{"name":"MK0653, ezetimibe","genericName":"MK0653, ezetimibe","slug":"mk0653-ezetimibe","phase":"phase_3","mechanism":"Ezetimibe inhibits cholesterol absorption in the small intestine by blocking the Niemann-Pick C1-Like 1 (NPC1L1) transporter.","indications":["Hypercholesterolemia (primary and secondary)","Homozygous familial hypercholesterolemia","Heterozygous familial hypercholesterolemia"],"catalyst":""},{"name":"MK0733, simvastatin","genericName":"MK0733, simvastatin","slug":"mk0733-simvastatin","phase":"phase_3","mechanism":"Simvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia and dyslipidemia","Primary and secondary prevention of cardiovascular disease"],"catalyst":""},{"name":"RecFSH / follitropin beta","genericName":"RecFSH / follitropin beta","slug":"recfsh-follitropin-beta","phase":"phase_3","mechanism":"RecFSH / follitropin beta stimulates the production of follicle-stimulating hormone, promoting ovulation and follicular growth.","indications":["Induction of ovulation and pregnancy in women with ovulatory disorders","Fertility preservation in cancer patients"],"catalyst":""},{"name":"Rizatriptan 10 mg","genericName":"Rizatriptan 10 mg","slug":"rizatriptan-10-mg","phase":"phase_3","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"etorocoxib","genericName":"etorocoxib","slug":"etorocoxib","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"ezetimibe/simvastatin 10/40","genericName":"ezetimibe/simvastatin 10/40","slug":"ezetimibe-simvastatin-10-40","phase":"phase_3","mechanism":"Ezetimibe/simvastatin reduces blood cholesterol by blocking intestinal cholesterol absorption (ezetimibe) and inhibiting hepatic cholesterol synthesis (simvastatin).","indications":["Hypercholesterolemia and mixed dyslipidemia","Cardiovascular risk reduction in patients requiring LDL-C lowering"],"catalyst":""},{"name":"fluticasone propionate hydrofluoroalkane (HFA)","genericName":"fluticasone propionate hydrofluoroalkane (HFA)","slug":"fluticasone-propionate-hydrofluoroalkane-hfa","phase":"marketed","mechanism":"Fluticasone propionate HFA is a potent inhaled corticosteroid that reduces airway inflammation by binding to glucocorticoid receptors.","indications":[],"catalyst":""},{"name":"rizatriptan benzoate (MK0462)","genericName":"rizatriptan benzoate (MK0462)","slug":"rizatriptan-benzoate-mk0462","phase":"phase_3","mechanism":"Rizatriptan benzoate is a selective serotonin 5-HT1B/1D receptor agonist, which is believed to relieve migraine headaches by causing vasoconstriction and inhibiting pro-inflammatory neuropeptide release.","indications":["Acute treatment of migraine attacks with or without aura"],"catalyst":""},{"name":"(rec)hCG","genericName":"(rec)hCG","slug":"rec-hcg","phase":"phase_3","mechanism":"Recombinant human chorionic gonadotropin (rec-hCG) mimics the natural hormone hCG to stimulate gonadal hormone production and support reproductive function.","indications":["Induction of ovulation in anovulatory women","Support of luteal phase in assisted reproductive technology (ART)","Treatment of hypogonadism in males"],"catalyst":""},{"name":"20-mg Desloratadine","genericName":"20-mg Desloratadine","slug":"20-mg-desloratadine","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Albuterol/Salbutamol PRN","genericName":"Albuterol/Salbutamol PRN","slug":"albuterol-salbutamol-prn","phase":"phase_3","mechanism":"Albuterol is a beta-2 adrenergic agonist that binds to beta-2 receptors on airway smooth muscle, causing rapid relaxation and bronchodilation.","indications":["Acute bronchospasm relief in asthma","Acute bronchospasm relief in chronic obstructive pulmonary disease (COPD)","Exercise-induced bronchoconstriction prevention"],"catalyst":""},{"name":"Amlodipine camsylate","genericName":"Amlodipine camsylate","slug":"amlodipine-camsylate","phase":"marketed","mechanism":"Amlodipine camsylate blocks L-type calcium channels in vascular smooth muscle and cardiac tissue, reducing calcium influx and causing vasodilation and decreased blood pressure.","indications":["Hypertension","Angina pectoris (chronic stable angina and vasospastic angina)"],"catalyst":""},{"name":"Asenapine - Double Blind","genericName":"Asenapine - Double Blind","slug":"asenapine-double-blind","phase":"phase_3","mechanism":"Asenapine is an atypical antipsychotic that blocks dopamine and serotonin receptors in the brain to reduce psychotic symptoms and mood disturbances.","indications":["Schizophrenia","Bipolar I disorder (acute manic or mixed episodes)"],"catalyst":""},{"name":"Asenapine - Open Label","genericName":"Asenapine - Open Label","slug":"asenapine-open-label","phase":"phase_3","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Asmanex twisthaler","genericName":"Asmanex twisthaler","slug":"asmanex-twisthaler","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Atorvastatin 10 mg","genericName":"Atorvastatin 10 mg","slug":"atorvastatin-10-mg","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Atorvastatin 80 mg","genericName":"Atorvastatin 80 mg","slug":"atorvastatin-80-mg","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Atovastatin","genericName":"Atovastatin","slug":"atovastatin","phase":"phase_3","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Beclomethasone dipropionate nasal spray","genericName":"Beclomethasone dipropionate nasal spray","slug":"beclomethasone-dipropionate-nasal-spray","phase":"phase_3","mechanism":"Beclomethasone dipropionate is a corticosteroid that reduces inflammation in the nasal passages by suppressing immune cell activity and inflammatory mediator release.","indications":["Allergic rhinitis","Nasal inflammation and congestion"],"catalyst":""},{"name":"Budesonide DPI","genericName":"Budesonide DPI","slug":"budesonide-dpi","phase":"phase_3","mechanism":"Budesonide is a corticosteroid that reduces inflammation by binding to glucocorticoid receptors and suppressing immune and inflammatory responses in the lungs.","indications":["Asthma (maintenance and reliever therapy)","Chronic obstructive pulmonary disease (COPD)"],"catalyst":""},{"name":"CE/MPA","genericName":"CE/MPA","slug":"ce-mpa","phase":"phase_3","mechanism":"CE/MPA is a combined oral contraceptive containing conjugated estrogens and medroxyprogesterone acetate that prevents ovulation and alters the uterine environment to inhibit pregnancy.","indications":["Contraception","Menstrual cycle regulation"],"catalyst":""},{"name":"Cetirizine (Zyrtec)","genericName":"Cetirizine (Zyrtec)","slug":"cetirizine-zyrtec","phase":"marketed","mechanism":"Cetirizine is a selective H1-receptor antagonist that blocks histamine binding to H1 receptors on cells, preventing allergic symptoms.","indications":["Allergic rhinitis (seasonal and perennial)","Chronic urticaria","Allergic conjunctivitis","Allergic dermatitis"],"catalyst":""},{"name":"Chlorpheniramine maleate syrup","genericName":"Chlorpheniramine maleate syrup","slug":"chlorpheniramine-maleate-syrup","phase":"phase_3","mechanism":"Chlorpheniramine maleate blocks histamine H1 receptors to reduce allergic symptoms and itching.","indications":["Allergic rhinitis","Urticaria and pruritus","Allergic reactions"],"catalyst":""},{"name":"Comparator: Diclofenac sodium","genericName":"Comparator: Diclofenac sodium","slug":"comparator-diclofenac-sodium","phase":"phase_3","mechanism":"Diclofenac sodium inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation, pain, and fever.","indications":["Acute pain and inflammation","Rheumatoid arthritis","Osteoarthritis","Ankylosing spondylitis","Postoperative pain"],"catalyst":""},{"name":"Comparator: Montelukast","genericName":"Comparator: Montelukast","slug":"comparator-montelukast","phase":"marketed","mechanism":"Montelukast blocks cysteinyl leukotriene receptors (CysLT1) on airway and immune cells, preventing leukotriene-mediated inflammation and bronchoconstriction.","indications":["Asthma (maintenance and acute prevention)","Allergic rhinitis","Aspirin-exacerbated respiratory disease (AERD)","Exercise-induced bronchoconstriction"],"catalyst":""},{"name":"Comparator: Placebo to ezetimibe/simvastatin","genericName":"Comparator: Placebo to ezetimibe/simvastatin","slug":"comparator-placebo-to-ezetimibe-simvastatin","phase":"phase_3","mechanism":"Ezetimibe/simvastatin is a combination that reduces cholesterol by blocking intestinal cholesterol absorption (ezetimibe) and inhibiting hepatic cholesterol synthesis (simvastatin).","indications":["Hypercholesterolemia and mixed dyslipidemia"],"catalyst":""},{"name":"Comparator: Salmeterol","genericName":"Comparator: Salmeterol","slug":"comparator-salmeterol","phase":"phase_3","mechanism":"Salmeterol is a long-acting beta-2 adrenergic agonist that binds to beta-2 receptors on airway smooth muscle to cause bronchodilation and improve airflow.","indications":["Asthma maintenance therapy","Chronic obstructive pulmonary disease (COPD) maintenance therapy"],"catalyst":""},{"name":"Comparator: amlodipine besylate","genericName":"Comparator: amlodipine besylate","slug":"comparator-amlodipine-besylate","phase":"phase_3","mechanism":"Amlodipine besylate is a calcium channel blocker that relaxes blood vessels and reduces blood pressure by inhibiting calcium influx into vascular smooth muscle cells.","indications":["Hypertension","Angina pectoris (chronic stable angina and vasospastic angina)"],"catalyst":""},{"name":"Comparator: atorvastatin","genericName":"Comparator: atorvastatin","slug":"comparator-atorvastatin","phase":"marketed","mechanism":"Atorvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia and dyslipidemia","Primary and secondary prevention of cardiovascular disease","Reduction of risk of myocardial infarction and stroke"],"catalyst":""},{"name":"Comparator: carvedilol","genericName":"Comparator: carvedilol","slug":"comparator-carvedilol","phase":"marketed","mechanism":"Carvedilol is a non-selective beta-adrenergic receptor antagonist with alpha-1 blocking activity that reduces heart rate, blood pressure, and cardiac workload.","indications":["Hypertension","Heart failure with reduced ejection fraction","Left ventricular dysfunction following myocardial infarction","Angina pectoris"],"catalyst":""},{"name":"Comparator: celecoxib","genericName":"Comparator: celecoxib","slug":"comparator-celecoxib","phase":"phase_3","mechanism":"Celecoxib selectively inhibits cyclooxygenase-2 (COX-2), reducing the production of prostaglandins that mediate inflammation and pain.","indications":["Rheumatoid arthritis","Osteoarthritis","Acute pain","Familial adenomatous polyposis (FAP)"],"catalyst":""},{"name":"Comparator: cetirizine","genericName":"Comparator: cetirizine","slug":"comparator-cetirizine","phase":"phase_3","mechanism":"Cetirizine is a selective H1-receptor antagonist that blocks histamine-mediated allergic responses without significant central nervous system penetration.","indications":["Allergic rhinitis (seasonal and perennial)","Chronic urticaria","Allergic conjunctivitis"],"catalyst":""},{"name":"Comparator: etoricoxib","genericName":"Comparator: etoricoxib","slug":"comparator-etoricoxib","phase":"phase_3","mechanism":"Etoricoxib selectively inhibits cyclooxygenase-2 (COX-2) to reduce prostaglandin production and inflammation.","indications":["Rheumatoid arthritis","Osteoarthritis","Ankylosing spondylitis","Acute pain","Chronic pain conditions"],"catalyst":""},{"name":"Comparator: fenofibrate monotherapy","genericName":"Comparator: fenofibrate monotherapy","slug":"comparator-fenofibrate-monotherapy","phase":"phase_3","mechanism":"Fenofibrate is a fibric acid derivative that activates peroxisome proliferator-activated receptor alpha (PPARα) to reduce triglycerides and increase HDL cholesterol.","indications":["Hypertriglyceridemia","Mixed dyslipidemia","Primary hypercholesterolemia (as adjunct to diet)"],"catalyst":""},{"name":"Comparator: fluvastatin","genericName":"Comparator: fluvastatin","slug":"comparator-fluvastatin","phase":"phase_3","mechanism":"Fluvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia and dyslipidemia for reduction of cardiovascular risk","Primary and secondary prevention of coronary heart disease"],"catalyst":""},{"name":"Comparator: ibuprofen","genericName":"Comparator: ibuprofen","slug":"comparator-ibuprofen","phase":"phase_3","mechanism":"Ibuprofen inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation, pain, and fever.","indications":["Mild to moderate pain","Fever reduction","Inflammatory conditions (e.g., rheumatoid arthritis, osteoarthritis)"],"catalyst":""},{"name":"Comparator: loratadine","genericName":"Comparator: loratadine","slug":"comparator-loratadine","phase":"phase_3","mechanism":"Loratadine is a selective H1-receptor antagonist that blocks histamine-mediated allergic responses without significant central nervous system penetration.","indications":["Allergic rhinitis (seasonal and perennial)","Chronic urticaria"],"catalyst":""},{"name":"Comparator: losartan +/- HCTZ","genericName":"Comparator: losartan +/- HCTZ","slug":"comparator-losartan-hctz","phase":"phase_3","mechanism":"Losartan is an angiotensin II receptor antagonist that blocks vasoconstriction and aldosterone secretion to lower blood pressure; HCTZ is a thiazide diuretic that reduces fluid volume.","indications":["Hypertension (as combination therapy or monotherapy with losartan)"],"catalyst":""},{"name":"Comparator: lovastatin","genericName":"Comparator: lovastatin","slug":"comparator-lovastatin","phase":"phase_3","mechanism":"Lovastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia","Primary prevention of coronary heart disease","Secondary prevention of coronary heart disease"],"catalyst":""},{"name":"Comparator: montelukast/loratadine","genericName":"Comparator: montelukast/loratadine","slug":"comparator-montelukast-loratadine","phase":"phase_3","mechanism":"This is a fixed-dose combination of montelukast (a cysteinyl leukotriene receptor antagonist) and loratadine (a selective H1-receptor antagonist) that reduces airway inflammation and blocks allergic mediators.","indications":["Allergic rhinitis and asthma (combination indication)"],"catalyst":""},{"name":"Comparator: naproxen sodium","genericName":"Comparator: naproxen sodium","slug":"comparator-naproxen-sodium","phase":"phase_3","mechanism":"Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation, pain, and fever.","indications":["Mild to moderate pain","Rheumatoid arthritis","Osteoarthritis","Menstrual cramps","Fever"],"catalyst":""},{"name":"Comparator: placebo, losartan, hydrochlorothiazide","genericName":"Comparator: placebo, losartan, hydrochlorothiazide","slug":"comparator-placebo-losartan-hydrochlorothiazide","phase":"phase_3","mechanism":"This drug is an angiotensin II receptor blocker (ARB) that lowers blood pressure by blocking the angiotensin II type 1 receptor, preventing vasoconstriction and aldosterone release.","indications":["Hypertension","Heart failure with reduced ejection fraction"],"catalyst":""},{"name":"Comparator: pranlukast","genericName":"Comparator: pranlukast","slug":"comparator-pranlukast","phase":"phase_3","mechanism":"Pranlukast is a cysteinyl leukotriene receptor antagonist that blocks the inflammatory effects of leukotrienes in the airways.","indications":["Asthma (allergic and exercise-induced)","Allergic rhinitis"],"catalyst":""},{"name":"Comparator: pravastatin","genericName":"Comparator: pravastatin","slug":"comparator-pravastatin","phase":"phase_3","mechanism":"Pravastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels and cardiovascular risk.","indications":["Hypercholesterolemia","Primary prevention of cardiovascular disease","Secondary prevention of cardiovascular events in patients with established coronary heart disease"],"catalyst":""},{"name":"Comparator: rizatriptan benzoate","genericName":"Comparator: rizatriptan benzoate","slug":"comparator-rizatriptan-benzoate","phase":"phase_3","mechanism":"Rizatriptan benzoate is a selective serotonin 5-HT1B/1D receptor agonist that constricts cranial blood vessels and inhibits neuropeptide release to relieve migraine headaches.","indications":["Acute migraine with or without aura"],"catalyst":""},{"name":"Comparator: statins","genericName":"Comparator: statins","slug":"comparator-statins","phase":"phase_3","mechanism":"Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia and dyslipidemia","Primary and secondary prevention of cardiovascular disease"],"catalyst":""},{"name":"Comparators: simvastatin and ezetimibe","genericName":"Comparators: simvastatin and ezetimibe","slug":"comparators-simvastatin-and-ezetimibe","phase":"phase_3","mechanism":"This is a combination therapy using simvastatin (a statin that inhibits HMG-CoA reductase) and ezetimibe (which blocks cholesterol absorption in the intestine) to lower LDL cholesterol through dual mechanisms.","indications":["Hypercholesterolemia / dyslipidemia for cardiovascular risk reduction"],"catalyst":""},{"name":"DRSP-EE","genericName":"DRSP-EE","slug":"drsp-ee","phase":"phase_3","mechanism":"DRSP-EE is a combined oral contraceptive containing drospirenone (a progestin) and ethinyl estradiol (an estrogen) that prevents ovulation and alters cervical mucus to inhibit fertilization.","indications":["Contraception (prevention of pregnancy)","Treatment of acne vulgaris (in females)","Treatment of premenstrual dysphoric disorder (PMDD)"],"catalyst":""},{"name":"Desloratadine (Clarinex)","genericName":"Desloratadine (Clarinex)","slug":"desloratadine-clarinex","phase":"phase_3","mechanism":"Desloratadine is a selective histamine H1-receptor antagonist that blocks histamine-mediated allergic responses without significant central nervous system penetration.","indications":["Allergic rhinitis (seasonal and perennial)","Chronic idiopathic urticaria"],"catalyst":""},{"name":"Desloratadine 5 mg","genericName":"Desloratadine 5 mg","slug":"desloratadine-5-mg","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Desloratadine placebo tablet","genericName":"Desloratadine placebo tablet","slug":"desloratadine-placebo-tablet","phase":"marketed","mechanism":"This is a placebo tablet containing no active pharmaceutical ingredient and therefore has no mechanistic effect.","indications":["Clinical trial control (not a therapeutic indication)"],"catalyst":""},{"name":"Double Atorvastatin","genericName":"Double Atorvastatin","slug":"double-atorvastatin","phase":"marketed","mechanism":"Double Atorvastatin is a statin that inhibits HMG-CoA reductase to reduce cholesterol synthesis and lower LDL cholesterol levels.","indications":["Hypercholesterolemia and dyslipidemia","Primary and secondary prevention of cardiovascular disease"],"catalyst":""},{"name":"Duration of Treatment: 3 months","genericName":"Duration of Treatment: 3 months","slug":"duration-of-treatment-3-months","phase":"phase_3","mechanism":"This drug works by inhibiting the activity of a specific enzyme.","indications":["Treatment of endometriosis","Treatment of uterine fibroids"],"catalyst":""},{"name":"Duration of Treatment: 6 weeks","genericName":"Duration of Treatment: 6 weeks","slug":"duration-of-treatment-6-weeks","phase":"phase_3","mechanism":"This drug works by inhibiting the activity of a specific enzyme.","indications":["Treatment of endometriosis","Treatment of uterine fibroids"],"catalyst":""},{"name":"Duration of Treatment: Z-Phase, 2 years.","genericName":"Duration of Treatment: Z-Phase, 2 years.","slug":"duration-of-treatment-z-phase-2-years","phase":"phase_3","mechanism":"Z-Phase is a medication that targets the body's natural processes to reduce inflammation and slow disease progression.","indications":["Moderate to severe rheumatoid arthritis","Psoriatic arthritis"],"catalyst":""},{"name":"E6005","genericName":"E6005","slug":"e6005","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"ENG 120 µg + EE 15 µg intravaginal ring","genericName":"ENG 120 µg + EE 15 µg intravaginal ring","slug":"eng-120-g-ee-15-g-intravaginal-ring","phase":"phase_3","mechanism":"This intravaginal ring releases etonogestrel (a progestin) and ethinyl estradiol (an estrogen) to prevent ovulation and provide contraception.","indications":["Contraception in women of reproductive age"],"catalyst":""},{"name":"Eptifibatide (Integrilin)","genericName":"Eptifibatide (Integrilin)","slug":"eptifibatide-integrilin","phase":"phase_3","mechanism":"Eptifibatide is a glycoprotein IIb/IIIa inhibitor that blocks platelet aggregation by preventing fibrinogen binding to platelet receptors.","indications":["Acute coronary syndrome (unstable angina and non-ST elevation myocardial infarction)","Percutaneous coronary intervention"],"catalyst":""},{"name":"Etidronate","genericName":"Etidronate","slug":"etidronate","phase":"phase_3","mechanism":"Type IV secretion-like conjugative transfer relaxase protein TraI","indications":["Heterotopic ossification","Humoral hypercalcemia of malignancy","Osteitis deformans"],"catalyst":""},{"name":"Etonogestrel-releasing IUS","genericName":"Etonogestrel-releasing IUS","slug":"etonogestrel-releasing-ius","phase":"phase_2","mechanism":"Etonogestrel-releasing IUS works by releasing a hormone that prevents ovulation and thickens cervical mucus to prevent sperm from reaching the egg.","indications":["Contraception for up to 5 years"],"catalyst":""},{"name":"Ezetimibe + Atorvastatin","genericName":"Ezetimibe + Atorvastatin","slug":"ezetimibe-atorvastatin","phase":"marketed","mechanism":"This combination reduces cholesterol by blocking intestinal cholesterol absorption (ezetimibe) and inhibiting HMG-CoA reductase to decrease hepatic cholesterol synthesis (atorvastatin).","indications":["Hypercholesterolemia and mixed dyslipidemia","Cardiovascular risk reduction in patients requiring LDL-C lowering"],"catalyst":""},{"name":"Ezetimibe + Simvastatin","genericName":"Ezetimibe + Simvastatin","slug":"ezetimibe-simvastatin","phase":"marketed","mechanism":"Ezetimibe and simvastatin work together to lower cholesterol by blocking intestinal cholesterol absorption and inhibiting hepatic cholesterol synthesis.","indications":["Hypercholesterolemia and mixed dyslipidemia","Cardiovascular risk reduction in patients requiring additional LDL-C lowering"],"catalyst":""},{"name":"FOSAMAX PLUS","genericName":"FOSAMAX PLUS","slug":"fosamax-plus","phase":"marketed","mechanism":"FOSAMAX PLUS combines alendronate (a bisphosphonate) with cholecalciferol (vitamin D3) to inhibit bone resorption and improve calcium absorption.","indications":["Osteoporosis in postmenopausal women","Osteoporosis in men","Glucocorticoid-induced osteoporosis"],"catalyst":""},{"name":"FOSAMAX PLUS D","genericName":"FOSAMAX PLUS D","slug":"fosamax-plus-d","phase":"marketed","mechanism":"FOSAMAX PLUS D combines alendronate (a bisphosphonate that inhibits bone resorption) with cholecalciferol (vitamin D3) to prevent and treat osteoporosis while ensuring adequate vitamin D status.","indications":["Osteoporosis prevention and treatment in postmenopausal women","Osteoporosis in men","Glucocorticoid-induced osteoporosis"],"catalyst":""},{"name":"Follitropin beta injection","genericName":"Follitropin beta injection","slug":"follitropin-beta-injection","phase":"phase_2","mechanism":"Stimulates the production of follicle-stimulating hormone (FSH)","indications":["Induction of ovulation in anovulatory infertile women, Assisted reproductive technology"],"catalyst":""},{"name":"Formoterol MDI","genericName":"Formoterol MDI","slug":"formoterol-mdi","phase":"phase_3","mechanism":"Formoterol is a long-acting beta-2 adrenergic agonist that binds to beta-2 receptors on airway smooth muscle to cause bronchodilation and improve airflow.","indications":["Asthma maintenance therapy","Chronic obstructive pulmonary disease (COPD) maintenance therapy"],"catalyst":""},{"name":"INEGY","genericName":"INEGY","slug":"inegy","phase":"phase_2","mechanism":"Selective estrogen receptor modulator","indications":["Hormone replacement therapy"],"catalyst":""},{"name":"LNG-EE","genericName":"LNG-EE","slug":"lng-ee","phase":"phase_3","mechanism":"LNG-EE is a combined oral contraceptive containing levonorgestrel (a progestin) and ethinyl estradiol (an estrogen) that prevents pregnancy by suppressing ovulation and altering cervical mucus.","indications":["Contraception / prevention of pregnancy","Regulation of menstrual cycles"],"catalyst":""},{"name":"Loratadine/montelukast combination","genericName":"Loratadine/montelukast combination","slug":"loratadine-montelukast-combination","phase":"phase_3","mechanism":"This combination blocks histamine H1 receptors (loratadine) and cysteinyl leukotriene receptors (montelukast) to reduce allergic and inflammatory responses in the airways.","indications":["Allergic rhinitis","Asthma with allergic component"],"catalyst":""},{"name":"Losartan (+) amlodipine","genericName":"Losartan (+) amlodipine","slug":"losartan-amlodipine","phase":"marketed","mechanism":"This combination blocks angiotensin II receptors and calcium channels to reduce blood pressure through vasodilation and decreased vascular resistance.","indications":["Hypertension"],"catalyst":""},{"name":"MK-0954A","genericName":"MK-0954A","slug":"mk-0954a","phase":"phase_3","mechanism":"MK-0954A is a selective antagonist of the neurokinin-1 (NK1) receptor that blocks substance P signaling in the central nervous system.","indications":["Chemotherapy-induced nausea and vomiting (CINV)","Postoperative nausea and vomiting (PONV)"],"catalyst":""},{"name":"MK-954H","genericName":"MK-954H","slug":"mk-954h","phase":"phase_3","mechanism":"MK-954H is a monoclonal antibody targeting the PD-1 receptor.","indications":["Non-small cell lung cancer, PD-L1 positive","Head and neck squamous cell carcinoma"],"catalyst":""},{"name":"MK0476; montelukast sodium","genericName":"MK0476; montelukast sodium","slug":"mk0476-montelukast-sodium","phase":"marketed","mechanism":"Montelukast sodium blocks cysteinyl leukotriene receptors (CysLT1) on airway and inflammatory cells, preventing leukotriene-mediated bronchoconstriction and inflammation.","indications":["Asthma (maintenance and prophylaxis)","Allergic rhinitis","Exercise-induced bronchoconstriction prophylaxis"],"catalyst":""},{"name":"MK0663, etoricoxib","genericName":"MK0663, etoricoxib","slug":"mk0663-etoricoxib","phase":"phase_3","mechanism":"Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2, reducing prostaglandin synthesis and inflammation.","indications":["Osteoarthritis","Rheumatoid arthritis"],"catalyst":""},{"name":"MK0733 / Duration of Treatment: 18 Weeks","genericName":"MK0733 / Duration of Treatment: 18 Weeks","slug":"mk0733-duration-of-treatment-18-weeks","phase":"phase_3","mechanism":"MK0733 is a selective antagonist of the neurokinin-1 (NK1) receptor that blocks substance P signaling in the central nervous system.","indications":["Chemotherapy-induced nausea and vomiting (CINV)","Postoperative nausea and vomiting (PONV)"],"catalyst":""},{"name":"MK0954, /Duration of Treatment : 16 Weeks","genericName":"MK0954, /Duration of Treatment : 16 Weeks","slug":"mk0954-duration-of-treatment-16-weeks","phase":"phase_3","mechanism":"MK0954 is a selective antagonist of the neurokinin-1 (NK1) receptor that blocks substance P signaling in the central nervous system.","indications":["Chronic pain conditions (Phase 3 development)"],"catalyst":""},{"name":"MK0954, /Duration of Treatment : 5 Years","genericName":"MK0954, /Duration of Treatment : 5 Years","slug":"mk0954-duration-of-treatment-5-years","phase":"phase_3","mechanism":"MK0954 is a selective antagonist of the neurokinin-1 (NK1) receptor that blocks substance P signaling in the central nervous system.","indications":["Chemotherapy-induced nausea and vomiting (CINV)","Postoperative nausea and vomiting (PONV)"],"catalyst":""},{"name":"Matching Placebo for Ibuprofen","genericName":"Matching Placebo for Ibuprofen","slug":"matching-placebo-for-ibuprofen","phase":"phase_3","mechanism":"This is an inert placebo formulation designed to match the appearance and administration of ibuprofen for use as a control in clinical trials.","indications":["Control arm in phase 3 clinical trials for ibuprofen efficacy and safety"],"catalyst":""},{"name":"Matching placebo nasal spray","genericName":"Matching placebo nasal spray","slug":"matching-placebo-nasal-spray","phase":"phase_3","mechanism":"A placebo nasal spray formulation containing no active pharmaceutical ingredient, used as a control comparator in clinical trials.","indications":[],"catalyst":""},{"name":"Mometasone Furoate (MF)","genericName":"Mometasone Furoate (MF)","slug":"mometasone-furoate-mf","phase":"phase_3","mechanism":"Mometasone furoate is a topical corticosteroid that suppresses local inflammatory and immune responses by binding to glucocorticoid receptors.","indications":["Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses","Allergic rhinitis (nasal formulation)"],"catalyst":""},{"name":"Mometasone Furoate MDI 200 mcg","genericName":"Mometasone Furoate MDI 200 mcg","slug":"mometasone-furoate-mdi-200-mcg","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Mometasone furoate dry powder inhaler","genericName":"Mometasone furoate dry powder inhaler","slug":"mometasone-furoate-dry-powder-inhaler","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Montelukast Oral Granules (OG)","genericName":"Montelukast Oral Granules (OG)","slug":"montelukast-oral-granules-og","phase":"phase_3","mechanism":"Montelukast blocks cysteinyl leukotriene receptors (CysLT1) on airway and inflammatory cells, preventing leukotriene-mediated bronchoconstriction and inflammation.","indications":["Asthma (prophylaxis and chronic treatment)","Allergic rhinitis","Exercise-induced bronchoconstriction"],"catalyst":""},{"name":"Montelukast chewable tablets","genericName":"Montelukast chewable tablets","slug":"montelukast-chewable-tablets","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Other Statin","genericName":"Other Statin","slug":"other-statin","phase":"marketed","mechanism":"Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.","indications":["Hypercholesterolemia","Primary prevention of cardiovascular disease","Secondary prevention of cardiovascular events"],"catalyst":""},{"name":"Phase 3 NOMAC-E2 \"Batch A\"","genericName":"Phase 3 NOMAC-E2 \"Batch A\"","slug":"phase-3-nomac-e2-batch-a","phase":"marketed","mechanism":"NOMAC-E2 is a combined oral contraceptive containing norethisterone acetate (progestin) and ethinyl estradiol (estrogen) that prevents pregnancy through ovulation suppression and cervical mucus thickening.","indications":["Contraception in women of reproductive age"],"catalyst":""},{"name":"Placebo Asenapine","genericName":"Placebo Asenapine","slug":"placebo-asenapine","phase":"phase_3","mechanism":"Asenapine is an atypical antipsychotic that blocks dopamine and serotonin receptors in the brain to reduce psychotic symptoms and mood disturbances.","indications":["Schizophrenia","Bipolar I disorder (acute manic or mixed episodes)"],"catalyst":""},{"name":"Placebo Corifollitropin alfa","genericName":"Placebo Corifollitropin alfa","slug":"placebo-corifollitropin-alfa","phase":"phase_3","mechanism":"Corifollitropin alfa is a long-acting follicle-stimulating hormone (FSH) analog that stimulates ovarian follicle development for assisted reproductive technology.","indications":["Controlled ovarian hyperstimulation in women undergoing assisted reproductive technology (ART) for infertility"],"catalyst":""},{"name":"Placebo for FDC EZ/Ator","genericName":"Placebo for FDC EZ/Ator","slug":"placebo-for-fdc-ez-ator","phase":"phase_3","mechanism":"This drug is a placebo, meaning it has no active therapeutic effect.","indications":["FDC EZ/Ator treatment for phase 3 clinical trials"],"catalyst":""},{"name":"Placebo for FP","genericName":"Placebo for FP","slug":"placebo-for-fp","phase":"phase_3","mechanism":"A placebo contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect.","indications":["FP (indication not specified)"],"catalyst":""},{"name":"Placebo for MF","genericName":"Placebo for MF","slug":"placebo-for-mf","phase":"phase_3","mechanism":"This drug has no known mechanism of action.","indications":[],"catalyst":""},{"name":"Placebo for MFNS","genericName":"Placebo for MFNS","slug":"placebo-for-mfns","phase":"phase_3","mechanism":"This drug is a placebo, meaning it has no active therapeutic effect.","indications":["Mild to moderate menopausal flushing"],"catalyst":""},{"name":"Placebo for SCH 900962","genericName":"Placebo for SCH 900962","slug":"placebo-for-sch-900962","phase":"phase_3","mechanism":"This is a placebo control with no active pharmacological mechanism.","indications":[],"catalyst":""},{"name":"Placebo for etoricoxib","genericName":"Placebo for etoricoxib","slug":"placebo-for-etoricoxib","phase":"marketed","mechanism":"A placebo contains no active pharmaceutical ingredient and produces no pharmacological effect.","indications":["Control arm in clinical trials for etoricoxib efficacy evaluation"],"catalyst":""},{"name":"Placebo for recFSH","genericName":"Placebo for recFSH","slug":"placebo-for-recfsh","phase":"phase_3","mechanism":"A placebo control arm used in clinical trials to evaluate the efficacy of recombinant follicle-stimulating hormone (recFSH) in fertility treatment.","indications":["Control arm in clinical trials for recombinant FSH in female infertility / assisted reproductive technology"],"catalyst":""},{"name":"Placebo to MK-0954A","genericName":"Placebo to MK-0954A","slug":"placebo-to-mk-0954a","phase":"phase_3","mechanism":"MK-0954A is a selective antagonist of the neurokinin-1 (NK1) receptor that blocks substance P signaling in the central nervous system.","indications":["Chemotherapy-induced nausea and vomiting (CINV)"],"catalyst":""},{"name":"Placebo to MK-954H","genericName":"Placebo to MK-954H","slug":"placebo-to-mk-954h","phase":"phase_3","mechanism":"Placebo to MK-954H does not have an active pharmacological mechanism; it is used as a control in clinical trials.","indications":[],"catalyst":""},{"name":"Placebo to budesonide inhaler","genericName":"Placebo to budesonide inhaler","slug":"placebo-to-budesonide-inhaler","phase":"marketed","mechanism":"Budesonide is a corticosteroid that reduces airway inflammation by binding to glucocorticoid receptors and suppressing inflammatory cytokine production.","indications":["Asthma maintenance therapy","Chronic obstructive pulmonary disease (COPD)"],"catalyst":""},{"name":"Placebo to etoricoxib","genericName":"Placebo to etoricoxib","slug":"placebo-to-etoricoxib","phase":"phase_3","mechanism":"Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2, reducing prostaglandin synthesis and inflammation.","indications":["Osteoarthritis","Rheumatoid arthritis"],"catalyst":""},{"name":"Placebo to ezetimibe/atorvastatin","genericName":"Placebo to ezetimibe/atorvastatin","slug":"placebo-to-ezetimibe-atorvastatin","phase":"phase_3","mechanism":"Ezetimibe inhibits the absorption of cholesterol in the small intestine, while atorvastatin inhibits HMG-CoA reductase to reduce cholesterol production in the liver.","indications":["Hyperlipidemia","Homozygous familial hypercholesterolemia"],"catalyst":""},{"name":"Placebo to ibuprofen","genericName":"Placebo to ibuprofen","slug":"placebo-to-ibuprofen","phase":"phase_3","mechanism":"Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for producing prostaglandins that cause pain and inflammation.","indications":["Relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, and other conditions"],"catalyst":""},{"name":"Placebo to match amlodipine","genericName":"Placebo to match amlodipine","slug":"placebo-to-match-amlodipine","phase":"marketed","mechanism":"This is an inert placebo formulation designed to match the appearance and administration of amlodipine for use in blinded clinical trials.","indications":["Use as control in clinical trials comparing amlodipine efficacy and safety"],"catalyst":""},{"name":"Placebo to match asenapine","genericName":"Placebo to match asenapine","slug":"placebo-to-match-asenapine","phase":"phase_3","mechanism":"This is an inert placebo formulation designed to match the physical and sensory characteristics of asenapine for blinded clinical trial comparisons.","indications":["Control comparator in phase 3 clinical trials of asenapine"],"catalyst":""},{"name":"Placebo to montelukast chewable tablets","genericName":"Placebo to montelukast chewable tablets","slug":"placebo-to-montelukast-chewable-tablets","phase":"marketed","mechanism":"Montelukast is a leukotriene receptor antagonist that blocks cysteinyl leukotriene receptors to reduce airway inflammation and bronchoconstriction.","indications":["Asthma (prophylaxis and chronic treatment)","Allergic rhinitis","Exercise-induced bronchoconstriction"],"catalyst":""},{"name":"Placebo vaginal ring","genericName":"Placebo vaginal ring","slug":"placebo-vaginal-ring","phase":"marketed","mechanism":"A placebo vaginal ring delivers no active pharmaceutical ingredient and serves as an inert control device for clinical trials.","indications":["Placebo control in clinical trials for vaginal ring contraceptives and hormone replacement therapies"],"catalyst":""},{"name":"Prednisone/Prednisolone","genericName":"Prednisone/Prednisolone","slug":"prednisone-prednisolone","phase":"marketed","mechanism":"Prednisone/prednisolone is a corticosteroid that binds to glucocorticoid receptors in the cytoplasm, translocates to the nucleus, and suppresses inflammatory gene expression and immune cell activation.","indications":["Rheumatoid arthritis and other autoimmune inflammatory conditions","Adrenocortical insufficiency (Addison's disease)","Allergic reactions and angioedema","Asthma and chronic obstructive pulmonary disease exacerbations","Systemic lupus erythematosus and other connective tissue diseases"],"catalyst":""},{"name":"Radiopaque Etonogestrel Implant","genericName":"Radiopaque Etonogestrel Implant","slug":"radiopaque-etonogestrel-implant","phase":"phase_3","mechanism":"A subdermal contraceptive implant that releases etonogestrel (a progestin) to prevent ovulation and thicken cervical mucus, with added radiopaque material for improved visibility on imaging.","indications":["Contraception in women of reproductive age"],"catalyst":""},{"name":"Radiopaque Implanon","genericName":"Radiopaque Implanon","slug":"radiopaque-implanon","phase":"phase_3","mechanism":"Radiopaque Implanon is a subdermal contraceptive implant containing etonogestrel that provides long-acting reversible contraception by suppressing ovulation through progestin delivery.","indications":["Long-acting reversible contraception in women of reproductive age"],"catalyst":""},{"name":"Simivastatin","genericName":"Simivastatin","slug":"simivastatin","phase":"phase_3","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"VTAMA (tapinarof) cream, 1%","genericName":"VTAMA (tapinarof) cream, 1%","slug":"vtama-tapinarof-cream-1","phase":"marketed","mechanism":"Tapinarof is an aryl hydrocarbon receptor (AhR) agonist that modulates immune responses in the skin to reduce inflammation and treat atopic dermatitis.","indications":["Atopic dermatitis (mild to moderate)"],"catalyst":""},{"name":"Vehicle Cream","genericName":"Vehicle Cream","slug":"vehicle-cream","phase":"marketed","mechanism":"Vehicle Cream is an inert topical formulation base used as a delivery system for active pharmaceutical ingredients in dermatological applications.","indications":["Pharmaceutical vehicle/excipient for topical dermatological formulations"],"catalyst":""},{"name":"Zyrtec® (cetirizine)","genericName":"Zyrtec® (cetirizine)","slug":"zyrtec-cetirizine","phase":"marketed","mechanism":"Cetirizine is a selective H1-receptor antagonist that blocks histamine binding to H1 receptors on cells, preventing allergic symptoms.","indications":["Seasonal and perennial allergic rhinitis","Chronic urticaria (hives)"],"catalyst":""},{"name":"aminophylline hydrate","genericName":"aminophylline hydrate","slug":"aminophylline-hydrate","phase":"phase_3","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"estradiol-norethisterone","genericName":"estradiol-norethisterone","slug":"estradiol-norethisterone","phase":"phase_3","mechanism":"Estradiol-norethisterone is a combination of an estrogen and a progestin that works by replacing natural hormones in the body.","indications":["Treatment of moderate to severe vasomotor symptoms associated with menopause","Prevention of postmenopausal osteoporosis"],"catalyst":""},{"name":"ezetimibe with simvastatin","genericName":"ezetimibe with simvastatin","slug":"ezetimibe-with-simvastatin","phase":"phase_3","mechanism":"Ezetimibe inhibits the absorption of cholesterol in the small intestine, while simvastatin is a statin that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis.","indications":["Hypercholesterolemia","Mixed dyslipidemia"],"catalyst":""},{"name":"fluticasone nasal spray","genericName":"fluticasone nasal spray","slug":"fluticasone-nasal-spray","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"loratadine; montelukast","genericName":"loratadine; montelukast","slug":"loratadine-montelukast","phase":"phase_3","mechanism":"Loratadine is an antihistamine that blocks the action of histamine, a substance in the body that causes allergy symptoms, while montelukast is a leukotriene receptor antagonist that blocks the action of leukotrienes, substances in the body that cause inflammation and constriction of airways.","indications":["Perennial allergic rhinitis","Chronic idiopathic urticaria","Asthma"],"catalyst":""},{"name":"low-dose estradiol/noresterone","genericName":"low-dose estradiol/noresterone","slug":"low-dose-estradiol-noresterone","phase":"marketed","mechanism":"Low-dose estradiol and noresterone work together as hormonal contraceptives by suppressing ovulation and altering cervical mucus and endometrial conditions to prevent pregnancy.","indications":["Contraception","Regulation of menstrual cycles"],"catalyst":""},{"name":"mometasone furoate nasal spray","genericName":"mometasone furoate nasal spray","slug":"mometasone-furoate-nasal-spray","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"open-label recFSH","genericName":"open-label recFSH","slug":"open-label-recfsh","phase":"phase_3","mechanism":"RecFSH stimulates follicular growth and ovulation in women with infertility.","indications":["Treatment of infertility in women"],"catalyst":""},{"name":"placebo nasal spray","genericName":"placebo nasal spray","slug":"placebo-nasal-spray","phase":"marketed","mechanism":"A placebo nasal spray contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect.","indications":[],"catalyst":""},{"name":"recFSH","genericName":"recFSH","slug":"recfsh","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""}],"recentEvents":[],"realNews":[{"url":"https://news.google.com/rss/articles/CBMiwgFBVV95cUxPUlVxOVY0aUpfeFFGc2lUVWRodDJjTzhHUy1lbnVkYVJpZ3NIWWtnMGI4WmtkNHVwYkx6TFg1bmRwX0gxZW42RExhdGoxc3NXS09WVFZaQ2lxX0NPcU5Lc1BLV1dqYzdjd2liYnExMEh6ZlJOb2I0RzdYTEw0bXYzY29sZ3RxTmlZTDJ2dXFma1ZHeEx6TklIaEpITEJ2dmJPeHVCTldpNGx1bTNtUDdmdzlELTd3ZzMtT09VX25kS0V0Zw?oc=5","date":"2026-03-25","type":"pipeline","source":"AD HOC NEWS","summary":"Organon & Co stock faces renewed scrutiny amid women's health sector shifts and pipeline updates - AD HOC NEWS","headline":"Organon & Co stock faces renewed scrutiny amid women's health sector shifts and pipeline updates","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMimwFBVV95cUxNZlVHaXpVWGJiTDdiNnlROXUzTmVWek5CTWQwLUlDUnNWMnZZNl91MEEwZ0lPVnU1N1VUTjkzQmtGMEZwemlzNzNZTXpNRWdjVzhxU3g0Z2hVOEkxWk9mc2RZVDA5OEpOTFY1aVA2OUFIbmZHZGdvTTNyVVZHY244V2VwWF9ySFRZUDVXZDdnYWlFSkxUb1pyTWNnNA?oc=5","date":"2026-02-23","type":"pipeline","source":"Finviz","summary":"Organon & Co. (OGN) Posts FY Adjusted EPS of $3.66, EBITDA Margin at 30.7% - Finviz","headline":"Organon & Co. (OGN) Posts FY Adjusted EPS of $3.66, EBITDA Margin at 30.7%","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiuwFBVV95cUxQeFRfcW5ERTFBaHpheXVSMUZYVlhHemswdy1GVnpKb3NjTW1XRFlya0lIOVpIRTBLV3FwU1dPcVpQWk1rVlRvZC1DUlRxSnFhcnFnV3c5ZFdFVGlyWGJWS2lWRWRrSlJCMVJDN0dkeWtveG5IUjlPZzgzWXJZQmJldUJTWU1lMnF4MlM1NVF3M3l5dFFvSGhndHd5T1JmRHJUa3diYnVZcVBVWEhHR3dOeDNUZy1Hb245d1pN?oc=5","date":"2026-01-23","type":"pipeline","source":"Sahm","summary":"Sun Pharma Bid Puts Organon Valuation And Growth Prospects In Focus - Sahm","headline":"Sun Pharma Bid Puts Organon Valuation And Growth Prospects In Focus","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMitgFBVV95cUxOaFFMZ0YwQ0cwZnZUd2ZJaE5lRzZIS09ZZDFYdGstYXRSNXlmeEJzVXpCYTJ5M0laSHc3RU05dHBDMlJBRWcwWUM3UmtnWXdybFdxYUJLbXRSY1RNU2NqVWNMdTZ1elYxLS1CMUJ2Zm1GMXdUMDVaQW1ST0p3M0V0cElWbDNzelRDZktJY0FobWZrS1VKdlZycFNQYm5YcFFNY0hYSThPdnc3Qy1VWXBNOURKVEJ3Zw?oc=5","date":"2026-01-21","type":"pipeline","source":"Bloomberg.com","summary":"India’s Biggest Pharma Firm Said to Mull Bid for New York-Listed Organon - Bloomberg.com","headline":"India’s Biggest Pharma Firm Said to Mull Bid for New York-Listed Organon","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiwwFBVV95cUxQLVk4MEJqTXFUal9Zc0tabHVjXzFSRU96VDdHZGNQWWRRUXdZUHBYSGxYOXVhZEMzNHZLYmJJbzlaY2E3X1JkZVVxUVRsZG1fb01Md0VYZUlVZTNuWXFVT3gwUUNBVkRxMjktM1NFa0RYRTcwRktNcERYVVQ5T1B5UUNiNWVqM09wOGpUdUVJMEVNVVNraGF0d2ZlU0o2Z01PUDJULWMxcFlRRVZfTU91SlFlaXRiS1daRXFKdWgwUUROV3c?oc=5","date":"2026-01-21","type":"pipeline","source":"Trefis","summary":"Organon Stock (+8%): Sun Pharma Bid Rumors Spark an M&A Chase - Trefis","headline":"Organon Stock (+8%): Sun Pharma Bid Rumors Spark an M&A Chase","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMizwFBVV95cUxNMENKaHJLS2dGeHRjS3RsclBrUjBjbndmc2V4Y0RTLVFqVVNoUDFGT2pFcjVGUUpabmljaDNGN2tmSmQzeVVhLUJIN0lEZ1Z6V0hfUUdNeVR4OUtaeEpBZlZ3SU5QdktrNllITU9xbF8xdlhOMm5GQWlwZTNjWV9DYXZ3Xzh3VGNIaUtDdFd1T0F5U2xMYXRUWXc0RlhpRFktVVJtWi1XRzBOek5ZOU9ieEdfWmVXVzd6WHhrb1dwa1V2YUkxMExpc1h1MVBkNFE?oc=5","date":"2026-01-20","type":"pipeline","source":"msn.com","summary":"Organon gains on report of Sun Pharmaceutical interest - msn.com","headline":"Organon gains on report of Sun Pharmaceutical interest","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiswFBVV95cUxQVmEzOTNHQ1d5VzdpWC03YzRVNVJjbHYybzBGN2RleS1QM3VjVWMxZm1rX3ZybEpEZzZuUTgzRTVZNXY4R0NNV0FobFNKdTJkcHM4WkZhVmYzSWV1clN4QUs0b0pwVW9uM0h6UEJJSnRFX1dXZ0d5WWxMUVZlbVFfbmxXa3o3SGtFWGVMRnFwM3JtUlc1cFNIM0E0X3VJSmVvRTBMX09xNXdRN0Rmd0NBT2otRQ?oc=5","date":"2026-01-20","type":"pipeline","source":"The Pharma Letter","summary":"BRIEF—Sun Pharma clarifies $10 billion Organon acquisition report - The Pharma Letter","headline":"BRIEF—Sun Pharma clarifies $10 billion Organon acquisition report","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiywFBVV95cUxNRXFYQ2NxRTB2Q1drLUliTFNMTkVKMVRoM3FBeGczem9va0VucFJIMHZXSENaVHhCTFBFeWZpTEtQRmhCbGg4Wnk5SnhCMDZLVF9yanY1X25qNThpcVNNZlpxbFhCTGZ2eHR6LUlTT2gxREJ3cEluNHJRZXE0TmFIekNvVF9FNW1qTW04MVNpSDBVMHhxRkxmTm1lTXpfWU1vNVFiOExGeDAyOWdPZ2V4STRTREFhTDRpT0xVeUhQdE42LWtNS0E4VFdCNA?oc=5","date":"2026-01-20","type":"deal","source":"Benzinga","summary":"Sun Pharma Eyes Organon In What Could Be India Pharma's Biggest Cross-Border Deal: Report - Benzinga","headline":"Sun Pharma Eyes Organon In What Could Be India Pharma's Biggest Cross-Border Deal: Report","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiU0FVX3lxTFBDNzF1R0FPZFh6U21oYmhOTFc5aGFwakJ6eTJxNVljaW1FaUF6WU1XaklsaEl5b3Q1d1dIWGFRUk5DVExpUkhNNEFmdVl0WXlqNm1r?oc=5","date":"2026-01-19","type":"deal","source":"FirstWord Pharma","summary":"Sun Pharma tight-lipped over rumoured $10B deal for Organon - FirstWord Pharma","headline":"Sun Pharma tight-lipped over rumoured $10B deal for Organon","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMihgFBVV95cUxNMGFaQks2aEVDNEdnSmt5LTV1ek5nODdyLVZNX18yU1FWVVNreXhDazd3SllTSnNjenM2VlRBNEJ1SHpodEJ1SDVsWHNsV0tIc1pHbW16U1RSY3l4cGhLNFpBSWxDTVc3T3BEaFlpLWYyTW5TeGxPd2JNUl9zNlpReEI4aGM3QQ?oc=5","date":"2026-01-19","type":"pipeline","source":"pharmaphorum","summary":"Sun Pharma says talk of $10bn Organon bid is 'speculative' - pharmaphorum","headline":"Sun Pharma says talk of $10bn Organon bid is 'speculative'","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiwgFBVV95cUxQUWFEd1VMMXA4ejZlTzBXbXJjb1JrbjZJYVpBbkVzU0F2T1FOQWZnMDlmQ00wZEc4ZEdlb2ZtM0VXU1NhYkI3Y2R0QzkxZkNPc3BnbXU1SDVUcmpYLTU3V1JucERjczY3SUtiRE4zanQwRFZfc05aY2xTeEpXY0pMVlhjYmJLSmI3ZndxbDBNWnVnYzFBODhXdDJPM3lwTkR4ekJYVUNfeUhNLU5PVG9rdmF4RGhxVFd4WUlKX0FwWHJkQQ?oc=5","date":"2026-01-19","type":"pipeline","source":"Investing.com","summary":"India’s Sun Pharma weighs $10 bln bid for US-listed Organon, ET reports - Investing.com","headline":"India’s Sun Pharma weighs $10 bln bid for US-listed Organon, ET reports","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMixgFBVV95cUxNSzBYMGVUX3l6ZElzNVd2QzU4eU5iaE5xRDRZOXZoNVg4S2RmeFp5RHE1emw3ZDRNcmc2TFU4MjJGcUxPakJoSVQtN2YxWU1mUVdLTGRGVEFMOHVXSEhsVE16Y094Q21OZS1qRW9ZOWotamJfczhqOEJXaDNyRG9jYUJ4bDFfNUtGaVh5MGJSdXhyNm9oWVZOZllscTlseHlHdzBRMUZKY1hvMDRsQlZHQ2RZNHZHakFnZkt4c3lRZzBXOHdsS2c?oc=5","date":"2025-10-27","type":"pipeline","source":"Fierce Pharma","summary":"Organon CEO exits, company goes on hunt for successor as internal probe turns up 'improper' Nexplanon sales tactics - Fierce Pharma","headline":"Organon CEO exits, company goes on hunt for successor as internal probe turns up 'improper' Nexplanon sales tactics","sentiment":"neutral"}],"patents":[],"drugCount":135,"phaseCounts":{"marketed":40,"phase_3":89,"phase_2":6},"enrichmentLevel":2,"visitCount":2,"keyCompetitors":[],"therapeuticFocus":[],"financials":null,"yahoo":null}