{"name":"Bayer AG","slug":"bayer","ticker":"BAYRY","exchange":"OTC","domain":"bayer.com","description":"Bayer AG is a German multinational pharmaceutical and biotechnology company and is one of the largest pharmaceutical companies and biomedical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceuticals, consumer healthcare products, agricultural chemicals, seeds and biotechnology products. 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vessels.","indications":["Chronic thromboembolic pulmonary hypertension","Pulmonary arterial hypertension"],"catalyst":""},{"name":"BAY1834845","genericName":"BAY1834845","slug":"bay1834845","phase":"phase_1","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY2253651","genericName":"BAY2253651","slug":"bay2253651","phase":"phase_2","mechanism":"BAY2253651 is a small molecule that targets the CDK9 protein.","indications":["Relapsed or refractory diffuse large B-cell lymphoma"],"catalyst":""},{"name":"BAY2927088","genericName":"BAY2927088","slug":"bay2927088","phase":"phase_3","mechanism":"BAY2927088 is a fibroblast growth factor receptor (FGFR) inhibitor that blocks FGFR signaling to inhibit tumor cell proliferation and survival.","indications":["Urothelial carcinoma with FGFR alterations","Other solid tumors with FGFR mutations or fusions"],"catalyst":""},{"name":"BAY86-6150","genericName":"BAY86-6150","slug":"bay86-6150","phase":"phase_2","mechanism":"BAY86-6150 is a small molecule that inhibits the SGLT2 receptor.","indications":["Type 2 diabetes"],"catalyst":""},{"name":"Betaseron","genericName":"INTERFERON BETA-1B","slug":"interferon-beta-1b","phase":"marketed","mechanism":"Betaseron works by binding to the interferon alpha/beta receptor, which helps to reduce inflammation and slow disease progression in multiple sclerosis.","indications":["Relapsing remitting multiple sclerosis"],"catalyst":""},{"name":"COMPLERA","genericName":"COMPLERA","slug":"complera","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Citomix","genericName":"INTERFERON","slug":"interferon","phase":"marketed","mechanism":"Recombinant protein","indications":["Seasonal colds"],"catalyst":""},{"name":"Estradiol (E2 0.3mg)","genericName":"Estradiol (E2 0.3mg)","slug":"estradiol-e2-0-3mg","phase":"phase_3","mechanism":"Estradiol is a naturally occurring estrogen that binds to estrogen receptors (ERα and ERβ) to modulate hormone-dependent physiological processes.","indications":["Menopausal vasomotor symptoms (hot flashes, night sweats)","Postmenopausal osteoporosis prevention","Estrogen deficiency states"],"catalyst":""},{"name":"Femstat 3","genericName":"BUTOCONAZOLE","slug":"butoconazole","phase":"marketed","mechanism":"Small molecule","indications":["Candidal vulvovaginitis"],"catalyst":""},{"name":"GBCAs","genericName":"GBCAs","slug":"gbcas","phase":"phase_2","mechanism":"Gadolinium-based contrast agents work by providing a contrast between the magnetic properties of tissues and the surrounding environment, allowing for better visualization of internal structures during MRI scans.","indications":["Contrast enhancement in MRI scans"],"catalyst":""},{"name":"HF medication","genericName":"HF medication","slug":"hf-medication","phase":"phase_2","mechanism":"Blocks the action of aldosterone","indications":["Hypertension","Heart 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Intubation"],"catalyst":""},{"name":"Mentax","genericName":"BUTENAFINE","slug":"butenafine","phase":"marketed","mechanism":"Cytochrome P450 2D6","indications":["Pityriasis versicolor","Tinea corporis","Tinea cruris","Tinea pedis"],"catalyst":""},{"name":"NAH therapy","genericName":"NAH therapy","slug":"nah-therapy","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Postinor 2","genericName":"Postinor 2","slug":"postinor-2","phase":"phase_1","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Precose","genericName":"ACARBOSE","slug":"acarbose","phase":"marketed","mechanism":"Sucrase-isomaltase, intestinal","indications":["Diabetes mellitus type 2"],"catalyst":""},{"name":"Raw Mashed Allium Cepa Application","genericName":"Raw Mashed Allium Cepa Application","slug":"raw-mashed-allium-cepa-application","phase":"phase_1","mechanism":"Biologic","indications":[],"catalyst":""},{"name":"Shade 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fusion gene-positive advanced or recurrent solid tumors"],"catalyst":""},{"name":"Voglibose (Basen)","genericName":"Voglibose (Basen)","slug":"voglibose-basen","phase":"marketed","mechanism":"Voglibose is an alpha-glucosidase inhibitor that slows the digestion and absorption of carbohydrates in the small intestine, reducing postprandial blood glucose levels.","indications":["Type 2 diabetes mellitus"],"catalyst":""},{"name":"Yasmin (EE30/DRSP, BAY86-5131)","genericName":"Yasmin (EE30/DRSP, BAY86-5131)","slug":"yasmin-ee30-drsp-bay86-5131","phase":"phase_3","mechanism":"Yasmin is a combination oral contraceptive that works by inhibiting ovulation through the estrogen and progestin components.","indications":["Dysmenorrhea","Acne","Hirsutism","Dysfunctional uterine bleeding","Emergency contraception"],"catalyst":""},{"name":"rFVIII (BAY81-8973) on demand","genericName":"rFVIII (BAY81-8973) on demand","slug":"rfviii-bay81-8973-on-demand","phase":"phase_3","mechanism":"rFVIII (BAY81-8973) is a recombinant factor VIII replacement therapy that mimics the natural protein to treat bleeding episodes in patients with hemophilia A.","indications":["On-demand treatment of bleeding episodes in patients with hemophilia A"],"catalyst":""},{"name":"A solution of 0.2% SLS","genericName":"A solution of 0.2% SLS","slug":"a-solution-of-0-2-sls","phase":"phase_1","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"AZLOCILLIN","genericName":"AZLOCILLIN","slug":"azlocillin","phase":"marketed","mechanism":"Small molecule","indications":["Aspiration pneumonia","Bacterial infection due to Klebsiella pneumoniae","Bacterial infection due to Serratia","Bacterial septicemia","Enterobacter Pneumonia"],"catalyst":""},{"name":"Acarbose (Glucobay, BAYG5421)","genericName":"Acarbose (Glucobay, BAYG5421)","slug":"acarbose-glucobay-bayg5421","phase":"marketed","mechanism":"Acarbose inhibits intestinal alpha-glucosidase enzymes to slow the digestion and absorption of carbohydrates, reducing postprandial blood glucose spikes.","indications":["Type 2 diabetes mellitus","Postprandial hyperglycemia in type 1 and type 2 diabetes"],"catalyst":""},{"name":"Adalat (Nifedipine, BAYA1040)","genericName":"Adalat (Nifedipine, BAYA1040)","slug":"adalat-nifedipine-baya1040","phase":"marketed","mechanism":"Nifedipine blocks calcium influx into vascular smooth muscle and cardiac cells, causing vasodilation and reduced blood pressure.","indications":["Hypertension","Angina pectoris (chronic stable angina)","Vasospastic angina (Prinzmetal's angina)"],"catalyst":""},{"name":"Advil","genericName":"Advil","slug":"advil","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Aliqopa","genericName":"COPANLISIB","slug":"copanlisib","phase":"marketed","mechanism":"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform","indications":["Follicular lymphoma"],"catalyst":""},{"name":"Alka Seltzer Extra Strength","genericName":"Alka Seltzer Extra Strength","slug":"alka-seltzer-extra-strength","phase":"marketed","mechanism":"Alka-Seltzer Extra Strength combines aspirin, citric acid, and sodium bicarbonate to neutralize stomach acid and provide analgesic and anti-inflammatory relief.","indications":["Heartburn and indigestion relief","Mild to moderate pain and fever","Acid reflux symptoms"],"catalyst":""},{"name":"Alka-Seltzer Gold","genericName":"GOLD","slug":"gold","phase":"marketed","mechanism":"Small molecule","indications":["Heartburn Relief","Acid Indigestion Relief","Sour Stomach Relief"],"catalyst":""},{"name":"Amlodipine (Norvasc)","genericName":"Amlodipine (Norvasc)","slug":"amlodipine-norvasc","phase":"marketed","mechanism":"Amlodipine blocks calcium channels in vascular smooth muscle and cardiac tissue, causing vasodilation and reduced blood pressure.","indications":["Hypertension","Angina pectoris (chronic stable angina and vasospastic angina)"],"catalyst":""},{"name":"Amoxicilline/clavulanic","genericName":"Amoxicilline/clavulanic","slug":"amoxicilline-clavulanic","phase":"phase_3","mechanism":"Amoxicillin/clavulanic acid is a beta-lactam antibiotic combination that kills bacteria by inhibiting cell wall synthesis, with clavulanic acid protecting amoxicillin from degradation by bacterial beta-lactamases.","indications":["Bacterial infections caused by beta-lactamase-producing organisms (respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media)"],"catalyst":""},{"name":"Anti-VEGF injections","genericName":"Anti-VEGF injections","slug":"anti-vegf-injections","phase":"phase_2","mechanism":"Anti-VEGF injections work by binding to and inhibiting vascular endothelial growth factor (VEGF), a protein that promotes angiogenesis.","indications":["Wet age-related macular degeneration","Macular edema following retinal vein occlusion","Diabetic macular edema"],"catalyst":""},{"name":"Antifibrinolytic treatment","genericName":"Antifibrinolytic treatment","slug":"antifibrinolytic-treatment","phase":"phase_2","mechanism":"Antifibrinolytic agents inhibit plasminogen activators and plasmin.","indications":["Treatment of bleeding in patients with hemophilia A or B","Prevention of excessive bleeding during and following surgery"],"catalyst":""},{"name":"Antithrombotic agents","genericName":"Antithrombotic agents","slug":"antithrombotic-agents","phase":"phase_2","mechanism":"Antithrombotic agents work by inhibiting platelet aggregation and preventing blood clots.","indications":["Atrial fibrillation for stroke prevention","Acute coronary syndrome","Deep vein thrombosis and pulmonary embolism"],"catalyst":""},{"name":"Any other OC","genericName":"Any other OC","slug":"any-other-oc","phase":"phase_2","mechanism":"Any other OC works by preventing ovulation.","indications":["Contraception"],"catalyst":""},{"name":"Aspirin 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3401016","slug":"bay-3401016","phase":"phase_2","mechanism":"Biologic","indications":[],"catalyst":""},{"name":"BAY 3547922","genericName":"BAY 3547922","slug":"bay-3547922","phase":"phase_1","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY 59-7939","genericName":"BAY 59-7939","slug":"bay-59-7939","phase":"phase_3","mechanism":"BAY 59-7939 is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent thrombus formation.","indications":["Thromboembolism prevention in patients undergoing hip or knee replacement surgery","Atrial fibrillation stroke prevention"],"catalyst":""},{"name":"BAY 77-1931","genericName":"BAY 77-1931","slug":"bay-77-1931","phase":"phase_2","mechanism":"BAY 77-1931 is a direct thrombin inhibitor that blocks the active site of thrombin to prevent blood clot formation.","indications":["Thromboembolism prevention and treatment"],"catalyst":""},{"name":"BAY 86-7660,levomefolate calcium","genericName":"BAY 86-7660,levomefolate 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targets the molecular target.","indications":["Phase 2 clinical trials for BAY3018250 are ongoing, but the specific indication is not publicly disclosed."],"catalyst":""},{"name":"BAY3283142","genericName":"BAY3283142","slug":"bay3283142","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY3498264","genericName":"BAY3498264","slug":"bay3498264","phase":"phase_1","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY3723113","genericName":"BAY3723113","slug":"bay3723113","phase":"phase_3","mechanism":"BAY3723113 is a selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) that blocks aberrant FGF/FGFR signaling in hepatocellular carcinoma and other cancers.","indications":["Hepatocellular carcinoma (HCC), FGFR4-positive or FGF19-positive"],"catalyst":""},{"name":"BAY60-4552 plus Vardenafil","genericName":"BAY60-4552 plus Vardenafil","slug":"bay60-4552-plus-vardenafil","phase":"phase_2","mechanism":"BAY60-4552 activates soluble guanylate cyclase to increase cGMP levels, while vardenafil inhibits phosphodiesterase-5 to prevent cGMP degradation, synergistically enhancing vasodilation and improving erectile function.","indications":["Erectile dysfunction","Pulmonary hypertension"],"catalyst":""},{"name":"BAY73-4506","genericName":"BAY73-4506","slug":"bay73-4506","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY85-3934","genericName":"BAY85-3934","slug":"bay85-3934","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY85-8501","genericName":"BAY85-8501","slug":"bay85-8501","phase":"phase_2","mechanism":"BAY85-8501 is a small molecule that targets the SGLT2 receptor.","indications":["Type 2 diabetes"],"catalyst":""},{"name":"BAY86-4891","genericName":"BAY86-4891","slug":"bay86-4891","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY86-4980","genericName":"BAY86-4980","slug":"bay86-4980","phase":"phase_3","mechanism":"BAY86-4980 is a selective inhibitor of phosphoinositide 3-kinase (PI3K) that blocks PI3K signaling to suppress tumor cell proliferation and survival.","indications":["Advanced or metastatic solid tumors with PI3K pathway alterations"],"catalyst":""},{"name":"BAY86-5016, SH P00331F","genericName":"BAY86-5016, SH P00331F","slug":"bay86-5016-sh-p00331f","phase":"phase_3","mechanism":"BAY86-5016 is a Factor IIa (thrombin) inhibitor that directly blocks the active site of thrombin to prevent blood clot formation.","indications":["Acute coronary syndrome","Thromboembolism prevention"],"catalyst":""},{"name":"BAY86-5046_Interferon-beta-1b","genericName":"BAY86-5046_Interferon-beta-1b","slug":"bay86-5046-interferon-beta-1b","phase":"phase_2","mechanism":"Interferon-beta-1b binds to the interferon-alpha/beta receptor, activating a signaling cascade that modulates immune responses.","indications":["Relapsing-remitting multiple sclerosis"],"catalyst":""},{"name":"BAY86-5300","genericName":"BAY86-5300","slug":"bay86-5300","phase":"phase_3","mechanism":"BAY86-5300 is a selective inhibitor of phosphoinositide 3-kinase (PI3K) that blocks PI3K signaling to suppress tumor cell proliferation and survival.","indications":["Advanced or metastatic solid tumors with PI3K pathway alterations"],"catalyst":""},{"name":"BAY86-5300_YAZ-Flex","genericName":"BAY86-5300_YAZ-Flex","slug":"bay86-5300-yaz-flex","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY94-8862","genericName":"BAY94-8862","slug":"bay94-8862","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"BAY94-9027","genericName":"BAY94-9027","slug":"bay94-9027","phase":"phase_3","mechanism":"BAY94-9027 is a long-acting factor VIII replacement therapy that extends the half-life of clotting factor VIII through PEGylation, reducing dosing frequency in hemophilia A patients.","indications":["Hemophilia A (routine prophylaxis and treatment of bleeding episodes)"],"catalyst":""},{"name":"BAY98-7443","genericName":"BAY98-7443","slug":"bay98-7443","phase":"phase_2","mechanism":"BAY98-7443 is a small molecule that acts as a selective and potent inhibitor of the sodium-glucose cotransporter 2 (SGLT2).","indications":["Treatment of type 2 diabetes"],"catalyst":""},{"name":"Bay 59-8862","genericName":"Bay 59-8862","slug":"bay-59-8862","phase":"phase_2","mechanism":"Bay 59-8862 is a selective and potent inhibitor of the sodium-glucose cotransporter 2 (SGLT2).","indications":["Type 2 diabetes"],"catalyst":""},{"name":"Baycol","genericName":"CERIVASTATIN","slug":"cerivastatin","phase":"marketed","mechanism":"3-hydroxy-3-methylglutaryl-coenzyme A reductase","indications":["Hypercholesterolemia","Mixed hyperlipidemia"],"catalyst":""},{"name":"Best standard of care (BSoC)","genericName":"Best standard of care (BSoC)","slug":"best-standard-of-care-bsoc","phase":"phase_3","mechanism":"Best standard of care (BSoC) is a comparator arm designation used in clinical trials, not a drug with a specific mechanism of action.","indications":[],"catalyst":""},{"name":"Betaferon, BAY86-5046","genericName":"Betaferon, BAY86-5046","slug":"betaferon-bay86-5046","phase":"phase_2","mechanism":"Betaferon is an immunomodulatory drug that works by inhibiting the production of interferon-gamma, a cytokine involved in the immune response.","indications":["Relapsing-remitting multiple sclerosis"],"catalyst":""},{"name":"Betaferon/Betaseron","genericName":"Betaferon/Betaseron","slug":"betaferon-betaseron","phase":"marketed","mechanism":"Betaferon is interferon beta-1b, which activates immune cells and reduces inflammatory responses in the central nervous system to slow disease progression.","indications":["Relapsing-remitting multiple sclerosis","Secondary progressive multiple sclerosis with active disease"],"catalyst":""},{"name":"Betapace","genericName":"sotalol","slug":"sotalol","phase":"marketed","mechanism":"Beta-1 adrenergic receptor, Beta-2 adrenergic receptor, Potassium voltage-gated channel subfamily H member 2","indications":["Atrial fibrillation","Life-Threatening Ventricular Tachycardia"],"catalyst":""},{"name":"Bifonazole cream 1%","genericName":"Bifonazole cream 1%","slug":"bifonazole-cream-1","phase":"phase_3","mechanism":"Bifonazole inhibits fungal cell membrane synthesis by disrupting ergosterol production through inhibition of lanosterol 14α-demethylase.","indications":["Fungal skin infections (dermatophytosis, candidiasis, pityriasis versicolor)","Topical treatment of tinea pedis, tinea corporis, and tinea cruris"],"catalyst":""},{"name":"Bifonazole spray once daily","genericName":"Bifonazole spray once daily","slug":"bifonazole-spray-once-daily","phase":"phase_2","mechanism":"Bifonazole is an antifungal agent that works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes.","indications":["Cutaneous candidiasis","Dermatophytosis"],"catalyst":""},{"name":"Bifonazole spray twice daily","genericName":"Bifonazole spray twice daily","slug":"bifonazole-spray-twice-daily","phase":"phase_2","mechanism":"Bifonazole is an antifungal agent that works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes.","indications":["Cutaneous candidiasis","Dermatophytosis"],"catalyst":""},{"name":"Butenafine HCl 1% (BAY1896425)","genericName":"Butenafine HCl 1% (BAY1896425)","slug":"butenafine-hcl-1-bay1896425","phase":"phase_3","mechanism":"Butenafine HCl is an allylamine antifungal that disrupts fungal cell membrane integrity by inhibiting squalene epoxidase, leading to ergosterol depletion.","indications":["Fungal skin infections (dermatophytosis, tinea pedis, tinea corporis, tinea cruris)"],"catalyst":""},{"name":"Ceftriaxone; Azithromycin; Amoxicilline/clavulanate; Clarithromycin","genericName":"Ceftriaxone; Azithromycin; Amoxicilline/clavulanate; Clarithromycin","slug":"ceftriaxone-azithromycin-amoxicilline-clavulanate-clarithromycin","phase":"phase_3","mechanism":"This is a combination of four beta-lactam and macrolide antibiotics that work by inhibiting bacterial cell wall synthesis and protein synthesis to kill or inhibit growth of susceptible bacteria.","indications":["Bacterial infections susceptible to beta-lactams and macrolides (respiratory tract infections, otitis media, sinusitis, skin infections)","Community-acquired pneumonia","Helicobacter pylori eradication (amoxicillin/clavulanate with clarithromycin)"],"catalyst":""},{"name":"Cipro","genericName":"ciprofloxacin","slug":"ciprofloxacin","phase":"marketed","mechanism":"DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A","indications":["Abdominal abscess","Acute Moraxella catarrhalis bronchitis","Acute bacterial bronchitis","Acute bacterial peritonitis","Acute bacterial sinusitis"],"catalyst":""},{"name":"Ciprofloxacin (BAYO9867)","genericName":"Ciprofloxacin (BAYO9867)","slug":"ciprofloxacin-bayo9867","phase":"phase_3","mechanism":"Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription in susceptible bacteria.","indications":["Bacterial infections (respiratory tract, urinary tract, gastrointestinal, skin and soft tissue)","Anthrax (inhalational exposure prophylaxis and treatment)"],"catalyst":""},{"name":"Ciprofloxacin DPI (BAYQ3939)","genericName":"Ciprofloxacin DPI (BAYQ3939)","slug":"ciprofloxacin-dpi-bayq3939","phase":"phase_3","mechanism":"Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription in susceptible bacteria.","indications":["Cystic fibrosis-associated Pseudomonas aeruginosa lung infection (inhaled formulation)","Respiratory tract infections caused by susceptible gram-negative and gram-positive bacteria"],"catalyst":""},{"name":"Ciprofloxacin single dose","genericName":"Ciprofloxacin single dose","slug":"ciprofloxacin-single-dose","phase":"phase_3","mechanism":"Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription in susceptible bacteria.","indications":["Acute bacterial infections (respiratory, urinary tract, gastrointestinal, skin)","Gonorrhea (single-dose regimen)","Traveler's diarrhea"],"catalyst":""},{"name":"Ciprofloxacin triple dose","genericName":"Ciprofloxacin triple dose","slug":"ciprofloxacin-triple-dose","phase":"phase_3","mechanism":"Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription in susceptible bacteria.","indications":["Bacterial infections (specific indication for triple-dose formulation in Phase 3 unknown; historically used for respiratory, urinary, gastrointestinal, and skin infections)"],"catalyst":""},{"name":"Clotrimazole, vaginal ovule","genericName":"Clotrimazole, vaginal ovule","slug":"clotrimazole-vaginal-ovule","phase":"phase_3","mechanism":"Clotrimazole disrupts fungal cell membrane integrity by inhibiting ergosterol synthesis, leading to cell death.","indications":["Vulvovaginal candidiasis"],"catalyst":""},{"name":"Conventional medical treatment","genericName":"Conventional medical treatment","slug":"conventional-medical-treatment","phase":"marketed","mechanism":"Conventional medical treatment refers to standard, evidence-based therapeutic approaches using established drugs and interventions rather than experimental or novel therapies.","indications":[],"catalyst":""},{"name":"Copanlisib (BAY 80-6946)","genericName":"Copanlisib (BAY 80-6946)","slug":"copanlisib-bay-80-6946","phase":"phase_3","mechanism":"Copanlisib is a pan-class I phosphatidylinositol 3-kinase (PI3K) inhibitor that blocks PI3K signaling to suppress tumor cell proliferation and survival.","indications":["Relapsed or refractory follicular lymphoma","Relapsed or refractory indolent non-Hodgkin lymphoma"],"catalyst":""},{"name":"Coracten","genericName":"Coracten","slug":"coracten","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"DOACs: Rivaroxaban, Dabigatran, Apixaban","genericName":"DOACs: Rivaroxaban, Dabigatran, Apixaban","slug":"doacs-rivaroxaban-dabigatran-apixaban","phase":"phase_2","mechanism":"Rivaroxaban, dabigatran, and apixaban are direct oral anticoagulants that inhibit Factor Xa or thrombin.","indications":["Atrial fibrillation for stroke prevention","Deep vein thrombosis and pulmonary embolism treatment and prevention"],"catalyst":""},{"name":"Dabigatran etexilate (Pradaxa)","genericName":"Dabigatran etexilate (Pradaxa)","slug":"dabigatran-etexilate-pradaxa","phase":"marketed","mechanism":"Dabigatran etexilate is a prodrug that converts to dabigatran, a direct thrombin inhibitor that blocks the final step of the coagulation cascade.","indications":["Atrial fibrillation for stroke and systemic embolism prevention","Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE)","Prophylaxis of DVT and PE following hip replacement surgery"],"catalyst":""},{"name":"Data on other treatments","genericName":"Data on other treatments","slug":"data-on-other-treatments","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Dehydroepiandrosterone, BAY86-5314","genericName":"Dehydroepiandrosterone, BAY86-5314","slug":"dehydroepiandrosterone-bay86-5314","phase":"phase_2","mechanism":"Dehydroepiandrosterone is a naturally occurring steroid hormone that has been investigated for its potential therapeutic effects.","indications":["Fatigue"],"catalyst":""},{"name":"Dexpanthenol (BAY81-2996)","genericName":"Dexpanthenol (BAY81-2996)","slug":"dexpanthenol-bay81-2996","phase":"marketed","mechanism":"Dexpanthenol is converted to pantothenic acid (vitamin B5), which serves as a precursor for coenzyme A, essential for cellular metabolism and tissue repair.","indications":["Wound healing and tissue repair","Dermatitis and skin irritation","Post-operative wound care","Minor burns and abrasions"],"catalyst":""},{"name":"Dexpanthenol foam spray, new formulation","genericName":"Dexpanthenol foam spray, new formulation","slug":"dexpanthenol-foam-spray-new-formulation","phase":"phase_2","mechanism":"Dexpanthenol, a form of vitamin B5, helps to soothe and protect the skin by promoting the healing of wounds and reducing inflammation.","indications":["Treatment of minor cuts and scrapes"],"catalyst":""},{"name":"Dexpanthenol foam spray, old formulation","genericName":"Dexpanthenol foam spray, old formulation","slug":"dexpanthenol-foam-spray-old-formulation","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Diagnostic procedures","genericName":"Diagnostic procedures","slug":"diagnostic-procedures","phase":"marketed","mechanism":"Diagnostic procedures are clinical or imaging techniques used to identify, visualize, or confirm the presence of disease or medical conditions.","indications":["General diagnostic imaging and clinical assessment across multiple therapeutic areas"],"catalyst":""},{"name":"Diane","genericName":"Diane","slug":"diane","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Diovan","genericName":"Diovan","slug":"diovan","phase":"marketed","mechanism":"Platelet glycoprotein VI, Type-1 angiotensin II receptor, Angiotensin II receptor (AT-1) type-1","indications":["Chronic heart failure","Hypertensive disorder","Left ventricular cardiac dysfunction"],"catalyst":""},{"name":"Diovan (Valsartan)","genericName":"Diovan (Valsartan)","slug":"diovan-valsartan","phase":"marketed","mechanism":"Valsartan blocks angiotensin II receptors on blood vessels and the heart, causing vasodilation and reducing blood pressure.","indications":["Hypertension","Heart failure (reduced ejection fraction)","Post-myocardial infarction with left ventricular dysfunction"],"catalyst":""},{"name":"Domeboro","genericName":"ALUMINUM ACETATE","slug":"aluminum-acetate","phase":"marketed","mechanism":"Small molecule","indications":["Skin irritation"],"catalyst":""},{"name":"Drospirenone/Ethinylestradiol/Methyltetrahydrofolate","genericName":"Drospirenone/Ethinylestradiol/Methyltetrahydrofolate","slug":"drospirenone-ethinylestradiol-methyltetrahydrofolate","phase":"phase_3","mechanism":"This combination oral contraceptive prevents pregnancy by suppressing ovulation through progestin and estrogen activity, while methyltetrahydrofolate supplementation reduces neural tube defect risk.","indications":["Contraception with reduced risk of neural tube defects"],"catalyst":""},{"name":"Drug: YAZ flex (SH T00186D)","genericName":"Drug: YAZ flex (SH T00186D)","slug":"drug-yaz-flex-sh-t00186d","phase":"phase_3","mechanism":"YAZ flex is an oral contraceptive that prevents ovulation through a combination of ethinyl estradiol and drospirenone, with a flexible dosing regimen.","indications":["Contraception","Treatment of premenstrual dysphoric disorder (PMDD)"],"catalyst":""},{"name":"EE20/DRSP (YAZ, BAY86-5300)","genericName":"EE20/DRSP (YAZ, BAY86-5300)","slug":"ee20-drsp-yaz-bay86-5300","phase":"marketed","mechanism":"EE20/DRSP is an oral contraceptive combining ethinyl estradiol and drospirenone to prevent ovulation and thicken cervical mucus.","indications":["Contraception","Acne vulgaris (moderate)","Premenstrual dysphoric disorder (PMDD)"],"catalyst":""},{"name":"EV/DNG (Qlaira, BAY86-5027)","genericName":"EV/DNG (Qlaira, BAY86-5027)","slug":"ev-dng-qlaira-bay86-5027","phase":"phase_3","mechanism":"EV/DNG is an estradiol valerate and dienogest combination oral contraceptive that prevents ovulation through hormonal suppression.","indications":["Contraception in women of reproductive age","Treatment of heavy menstrual bleeding in women desiring contraception"],"catalyst":""},{"name":"Elinzanetant (BAY3427080)","genericName":"Elinzanetant (BAY3427080)","slug":"elinzanetant-bay3427080","phase":"phase_3","mechanism":"Elinzanetant is a neurokinin-3 (NK3) receptor antagonist that reduces vasomotor symptoms by blocking neurokinin signaling in the hypothalamus.","indications":["Vasomotor symptoms (hot flashes and night sweats) associated with menopause"],"catalyst":""},{"name":"Enoxaparin followed by VKA","genericName":"Enoxaparin followed by VKA","slug":"enoxaparin-followed-by-vka","phase":"phase_3","mechanism":"Enoxaparin is a low-molecular-weight heparin that inhibits blood clotting factors, followed by a vitamin K antagonist (VKA) to maintain long-term anticoagulation.","indications":["Venous thromboembolism (DVT/PE) treatment and prevention","Acute coronary syndrome","Atrial fibrillation for stroke prevention"],"catalyst":""},{"name":"Eovist","genericName":"gadoxetate","slug":"gadoxetate","phase":"marketed","mechanism":"Eovist works by accumulating in liver cells and providing a contrast signal in MRI scans.","indications":["Liver MRI for lesion detection and characterization"],"catalyst":""},{"name":"Ertapenem intravenous","genericName":"Ertapenem intravenous","slug":"ertapenem-intravenous","phase":"phase_3","mechanism":"Ertapenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.","indications":["Complicated intra-abdominal infections","Complicated skin and soft tissue infections","Community-acquired pneumonia","Complicated urinary tract infections","Acute pelvic infections"],"catalyst":""},{"name":"FVIII products","genericName":"FVIII products","slug":"fviii-products","phase":"phase_2","mechanism":"FVIII products replace or supplement the missing or defective clotting factor VIII in the blood to help the blood to clot normally.","indications":["Hemophilia A","Hemophilia A with inhibitors"],"catalyst":""},{"name":"Finerenone (BAY94-8862)","genericName":"Finerenone (BAY94-8862)","slug":"finerenone-bay94-8862","phase":"phase_3","mechanism":"Finerenone is a non-steroidal mineralocorticoid receptor antagonist that blocks aldosterone signaling to reduce inflammation and fibrosis in the kidneys and cardiovascular system.","indications":["Chronic kidney disease in patients with type 2 diabetes","Diabetic kidney disease"],"catalyst":""},{"name":"Gadavist","genericName":"GADOBUTROL","slug":"gadobutrol","phase":"marketed","mechanism":"Gadavist works by binding to gadolinium ions, which then accumulate in body tissues and enhance MRI signal.","indications":["Magnetic resonance imaging"],"catalyst":""},{"name":"Gadoquatrane (BAY1747846)","genericName":"Gadoquatrane (BAY1747846)","slug":"gadoquatrane-bay1747846","phase":"phase_3","mechanism":"Gadoquatrane is a gadolinium-based contrast agent designed for magnetic resonance imaging (MRI) that provides enhanced visualization of blood vessels and tissues.","indications":["Magnetic resonance imaging (MRI) contrast enhancement for vascular and tissue imaging"],"catalyst":""},{"name":"Gadoterate (Dotarem/Clariscan)","genericName":"Gadoterate (Dotarem/Clariscan)","slug":"gadoterate-dotarem-clariscan","phase":"marketed","mechanism":"Gadoterate is a gadolinium-based contrast agent that accumulates in tissues and enhances MRI signal to improve visualization of anatomical structures and lesions.","indications":["MRI contrast enhancement for central nervous system imaging","MRI contrast enhancement for body imaging including cardiovascular and abdominal applications"],"catalyst":""},{"name":"Gadoteridol (ProHance)","genericName":"Gadoteridol (ProHance)","slug":"gadoteridol-prohance","phase":"phase_3","mechanism":"Gadoteridol is a gadolinium-based contrast agent that enhances magnetic resonance imaging (MRI) by shortening the T1 relaxation time of water protons in tissues.","indications":["MRI contrast enhancement for central nervous system imaging","MRI contrast enhancement for body imaging including liver, kidney, and other organs"],"catalyst":""},{"name":"Gynodian® Depot (BAY86-5032)","genericName":"Gynodian® Depot (BAY86-5032)","slug":"gynodian-depot-bay86-5032","phase":"phase_3","mechanism":"Gynodian Depot is a long-acting gonadotropin-releasing hormone (GnRH) agonist that suppresses luteinizing hormone and follicle-stimulating hormone to reduce estrogen levels.","indications":["Endometriosis","Uterine fibroids (leiomyomas)"],"catalyst":""},{"name":"Ibuprofen (Advil)","genericName":"Ibuprofen (Advil)","slug":"ibuprofen-advil","phase":"marketed","mechanism":"Ibuprofen inhibits cyclooxygenase (COX) enzymes to reduce the production of prostaglandins, thereby decreasing inflammation, pain, and fever.","indications":["Mild to moderate pain","Fever reduction","Inflammation associated with headache, muscular aches, backache, minor arthritis pain, menstrual cramps, and the common cold"],"catalyst":""},{"name":"Interferon beta-1b, FRP within 15 days after randomization","genericName":"Interferon beta-1b, FRP within 15 days after randomization","slug":"interferon-beta-1b-frp-within-15-days-after-randomization","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Intracervical lidocaine","genericName":"Intracervical lidocaine","slug":"intracervical-lidocaine","phase":"marketed","mechanism":"Intracervical lidocaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission in cervical tissue.","indications":["Cervical anesthesia during gynecological procedures","Pain relief during cervical examination or instrumentation"],"catalyst":""},{"name":"Iotrol","genericName":"IOTROLAN","slug":"iotrolan","phase":"marketed","mechanism":"","indications":[],"catalyst":""},{"name":"Kogenate (BAY 14-2222)","genericName":"Kogenate (BAY 14-2222)","slug":"kogenate-bay-14-2222","phase":"marketed","mechanism":"Kogenate is a recombinant human coagulation factor VIII that replaces deficient or dysfunctional factor VIII to restore blood clotting ability in hemophilia A patients.","indications":["Hemophilia A (congenital factor VIII deficiency) — treatment and prevention of bleeding episodes","Perioperative management in hemophilia A patients"],"catalyst":""},{"name":"Kogenate (BAY14-2222)","genericName":"Kogenate (BAY14-2222)","slug":"kogenate-bay14-2222","phase":"marketed","mechanism":"Kogenate is a recombinant human coagulation factor VIII that replaces deficient or dysfunctional factor VIII to restore blood clotting ability in hemophilia A patients.","indications":["Hemophilia A (congenital factor VIII deficiency) — prevention and treatment of bleeding episodes","Perioperative management in hemophilia A patients"],"catalyst":""},{"name":"Kyleena","genericName":"Kyleena","slug":"kyleena","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"LCS12","genericName":"LCS12","slug":"lcs12","phase":"phase_3","mechanism":"LCS12 is a small molecule that inhibits the PCSK9 enzyme.","indications":["Hypercholesterolemia"],"catalyst":""},{"name":"LCS16","genericName":"LCS16","slug":"lcs16","phase":"phase_3","mechanism":"LCS16 is a small molecule that inhibits the PCSK9 enzyme.","indications":["Hypercholesterolemia"],"catalyst":""},{"name":"LNG-IUS (BAY 86-5028)","genericName":"LNG-IUS (BAY 86-5028)","slug":"lng-ius-bay-86-5028","phase":"phase_3","mechanism":"LNG-IUS is a levonorgestrel-releasing intrauterine system that provides long-acting reversible contraception by releasing a synthetic progestin directly into the uterus.","indications":["Contraception (long-acting reversible)","Heavy menstrual bleeding (off-label/secondary indication)"],"catalyst":""},{"name":"Laif® 900, BAY98-7108","genericName":"Laif® 900, BAY98-7108","slug":"laif-900-bay98-7108","phase":"phase_3","mechanism":"Laif 900 is a standardized St. John's Wort extract that modulates serotonin and other neurotransmitter systems to improve mood in depression.","indications":["Mild to moderate depression"],"catalyst":""},{"name":"Lampit","genericName":"NIFURTIMOX","slug":"nifurtimox","phase":"marketed","mechanism":"Lampit works by releasing reactive oxygen species that damage the DNA of Trypanosoma cruzi, ultimately killing the parasite.","indications":["Infection by Trypanosoma cruzi"],"catalyst":""},{"name":"Levofloxacin + Ceftriaxone","genericName":"Levofloxacin + Ceftriaxone","slug":"levofloxacin-ceftriaxone","phase":"phase_3","mechanism":"This combination uses a fluoroquinolone antibiotic to inhibit bacterial DNA gyrase and topoisomerase IV, while a third-generation cephalosporin inhibits bacterial cell wall synthesis, providing broad-spectrum coverage against gram-positive and gram-negative bacteria.","indications":["Community-acquired pneumonia","Complicated urinary tract infections","Intra-abdominal infections","Bacterial infections requiring broad-spectrum coverage"],"catalyst":""},{"name":"Levonorgestrel (BAY98-7196)","genericName":"Levonorgestrel (BAY98-7196)","slug":"levonorgestrel-bay98-7196","phase":"phase_3","mechanism":"Levonorgestrel is a synthetic progestin that prevents pregnancy by suppressing ovulation and altering cervical mucus and endometrial conditions.","indications":["Oral contraception","Emergency contraception"],"catalyst":""},{"name":"Lotrimin","genericName":"clotrimazole","slug":"clotrimazole","phase":"marketed","mechanism":"7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, Malate dehydrogenase cytoplasmic , 5-hydroxytryptamine receptor 6","indications":["Candidal vulvovaginitis","Candidiasis of mouth","Candidiasis of skin","Diaper rash","Oropharyngeal Candidiasis"],"catalyst":""},{"name":"Lotrimin Daily Sweat and Odor Control","genericName":"STARCH","slug":"starch","phase":"marketed","mechanism":"","indications":["minor skin irritation"],"catalyst":""},{"name":"Macrogol (Forlax)","genericName":"Macrogol (Forlax)","slug":"macrogol-forlax","phase":"marketed","mechanism":"Macrogol is an osmotic laxative that draws water into the intestinal lumen to soften stool and promote bowel movements.","indications":["Constipation (functional and occasional)","Bowel preparation prior to colonoscopy or other gastrointestinal procedures"],"catalyst":""},{"name":"Magnevist (SH L 451A)","genericName":"Magnevist (SH L 451A)","slug":"magnevist-sh-l-451a","phase":"phase_3","mechanism":"Magnevist is a gadolinium-based contrast agent that enhances magnetic resonance imaging (MRI) by shortening the T1 relaxation time of water protons in tissues.","indications":["MRI contrast enhancement for central nervous system imaging","MRI contrast enhancement for body imaging including cardiovascular and abdominal applications"],"catalyst":""},{"name":"Mercilon","genericName":"Mercilon","slug":"mercilon","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Minisiston (SH D00342A)","genericName":"Minisiston (SH D00342A)","slug":"minisiston-sh-d00342a","phase":"phase_3","mechanism":"Minisiston is a progestin-only oral contraceptive that prevents pregnancy primarily through cervical mucus thickening and endometrial suppression.","indications":["Oral contraception for pregnancy prevention"],"catalyst":""},{"name":"Mirena (BAY86-5028)","genericName":"Mirena (BAY86-5028)","slug":"mirena-bay86-5028","phase":"marketed","mechanism":"Mirena releases levonorgestrel directly into the uterus to prevent pregnancy and reduce menstrual bleeding through local hormonal suppression.","indications":["Contraception","Heavy menstrual bleeding (menorrhagia)"],"catalyst":""},{"name":"Molidustat (BAY85-3934)","genericName":"Molidustat (BAY85-3934)","slug":"molidustat-bay85-3934","phase":"phase_3","mechanism":"Molidustat activates hypoxia-inducible factor prolyl hydroxylase (HIF-PH) enzymes, leading to stabilization of HIF-α subunits and increased erythropoietin production.","indications":["Anemia associated with chronic kidney disease (CKD) in adults not on dialysis","Anemia associated with CKD in adults on dialysis"],"catalyst":""},{"name":"Musredo","genericName":"MOLIDUSTAT","slug":"molidustat","phase":"marketed","mechanism":"Egl nine homolog 1","indications":["Renal anemia"],"catalyst":""},{"name":"Naproxen sodium ER (BAYH6689)","genericName":"Naproxen sodium ER (BAYH6689)","slug":"naproxen-sodium-er-bayh6689","phase":"phase_3","mechanism":"Naproxen sodium ER is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain.","indications":["Chronic pain management","Osteoarthritis","Rheumatoid arthritis"],"catalyst":""},{"name":"Nifedipine (Adalat, BAYA1040)","genericName":"Nifedipine (Adalat, BAYA1040)","slug":"nifedipine-adalat-baya1040","phase":"marketed","mechanism":"Nifedipine blocks L-type calcium channels in vascular smooth muscle and cardiac tissue, reducing calcium influx and causing vasodilation and decreased cardiac contractility.","indications":["Hypertension","Angina pectoris","Coronary artery spasm (Prinzmetal's angina)"],"catalyst":""},{"name":"Nifedipine/Telmisartan","genericName":"Nifedipine/Telmisartan","slug":"nifedipine-telmisartan","phase":"marketed","mechanism":"This combination reduces blood pressure by blocking calcium channels (nifedipine) to relax blood vessels and blocking angiotensin II receptors (telmisartan) to prevent vasoconstriction.","indications":["Hypertension"],"catalyst":""},{"name":"Nifidipine","genericName":"Nifidipine","slug":"nifidipine","phase":"marketed","mechanism":"Small molecule","indications":[],"catalyst":""},{"name":"Nifurtimox (Lampit, BAYA2502)","genericName":"Nifurtimox (Lampit, BAYA2502)","slug":"nifurtimox-lampit-baya2502","phase":"phase_3","mechanism":"Nifurtimox is a nitrofuran compound that generates reactive oxygen species to kill parasites, particularly effective against Trypanosoma cruzi.","indications":["Chagas disease (Trypanosoma cruzi infection)","Phase 3 investigation for additional parasitic or infectious indications (specific indication not publicly detailed)"],"catalyst":""},{"name":"Non-quinolone antibiotic","genericName":"Non-quinolone antibiotic","slug":"non-quinolone-antibiotic","phase":"phase_3","mechanism":"Non-quinolone antibiotics inhibit bacterial protein synthesis or cell wall formation through mechanisms distinct from fluoroquinolone drugs.","indications":["Bacterial infections (specific indication unknown without drug identity)"],"catalyst":""},{"name":"Phosphestrol","genericName":"fosfestrol","slug":"fosfestrol","phase":"marketed","mechanism":"Estrogen receptor","indications":[],"catalyst":""},{"name":"Piperacillin/Tazobactam & Amoxicillin/Clavulanic acid","genericName":"Piperacillin/Tazobactam & Amoxicillin/Clavulanic acid","slug":"piperacillin-tazobactam-amoxicillin-clavulanic-acid","phase":"phase_3","mechanism":"Piperacillin/Tazobactam is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis, while Amoxicillin/Clavulanic acid is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis and is protected from beta-lactamase degradation by Clavulanic acid.","indications":["Treatment of complicated urinary tract infections, complicated intra-abdominal infections, and nosocomial pneumonia","Treatment of skin and soft tissue infections"],"catalyst":""},{"name":"Placebo (10 mg)","genericName":"Placebo (10 mg)","slug":"placebo-10-mg","phase":"phase_3","mechanism":"Placebo produces therapeutic effects through patient expectation and the psychobiological placebo response, rather than through a pharmacologically active ingredient.","indications":["Clinical trial control comparator (non-therapeutic use)"],"catalyst":""},{"name":"Placebo Match to SH D593B","genericName":"Placebo Match to SH D593B","slug":"placebo-match-to-sh-d593b","phase":"phase_3","mechanism":"This is a placebo formulation designed to match the physical and sensory characteristics of the active investigational drug SH D593B in clinical trials.","indications":[],"catalyst":""},{"name":"Placebo Match to SH T00658ID","genericName":"Placebo Match to SH T00658ID","slug":"placebo-match-to-sh-t00658id","phase":"phase_3","mechanism":"This is a placebo control formulation designed to match the appearance and administration characteristics of an active investigational drug (SH T00658ID) in a Phase 3 clinical trial.","indications":[],"catalyst":""},{"name":"Placebo of Darbepoetin alfa","genericName":"Placebo of Darbepoetin alfa","slug":"placebo-of-darbepoetin-alfa","phase":"phase_3","mechanism":"Darbepoetin alfa is an erythropoiesis-stimulating protein that mimics the action of erythropoietin to stimulate red blood cell production.","indications":["Anemia associated with chronic kidney disease","Anemia associated with cancer chemotherapy"],"catalyst":""},{"name":"Placebo: syringes of Enoxaparin","genericName":"Placebo: syringes of Enoxaparin","slug":"placebo-syringes-of-enoxaparin","phase":"phase_3","mechanism":"Enoxaparin is a low-molecular-weight heparin that inhibits blood clotting by enhancing the activity of antithrombin III against factors Xa and IIa.","indications":["Prophylaxis of venous thromboembolism in surgical patients","Treatment of acute deep vein thrombosis","Treatment of acute pulmonary embolism","Prophylaxis in medically ill patients at risk of thromboembolism"],"catalyst":""},{"name":"Placebo: tablet of Rivaroxaban","genericName":"Placebo: tablet of Rivaroxaban","slug":"placebo-tablet-of-rivaroxaban","phase":"phase_3","mechanism":"Rivaroxaban is a direct Factor Xa inhibitor that prevents the coagulation cascade.","indications":["Deep vein thrombosis","Pulmonary embolism","Atrial fibrillation for stroke prevention","Acute coronary syndrome"],"catalyst":""},{"name":"Pradaxa (Dabigatran etexilate)","genericName":"Pradaxa (Dabigatran etexilate)","slug":"pradaxa-dabigatran-etexilate","phase":"marketed","mechanism":"Dabigatran etexilate is a direct thrombin inhibitor that blocks the final step of the coagulation cascade by directly binding to and inhibiting thrombin.","indications":["Atrial fibrillation for stroke and systemic embolism prevention","Treatment of deep vein thrombosis and pulmonary embolism","Prophylaxis of deep vein thrombosis and pulmonary embolism following hip replacement surgery"],"catalyst":""},{"name":"Prilosec OTC™ Tablets","genericName":"Prilosec OTC™ 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disorders.","indications":["Uterine fibroids (leiomyomas)","Endometriosis"],"catalyst":""},{"name":"SH P00331N","genericName":"SH P00331N","slug":"sh-p00331n","phase":"phase_3","mechanism":"SH P00331N is a small molecule drug that targets the SGLT2 receptor.","indications":["Type 2 diabetes"],"catalyst":""},{"name":"SPF 15 Control","genericName":"SPF 15 Control","slug":"spf-15-control","phase":"marketed","mechanism":"SPF 15 Control is a sunscreen that provides ultraviolet (UV) radiation protection by absorbing and reflecting UVA and UVB rays.","indications":["UV protection and sunburn prevention"],"catalyst":""},{"name":"STW5 (Iberogast, BAY98-7411)","genericName":"STW5 (Iberogast, BAY98-7411)","slug":"stw5-iberogast-bay98-7411","phase":"phase_3","mechanism":"STW5 is a herbal combination product that modulates gastric motility and secretion to improve digestive function and reduce functional gastrointestinal symptoms.","indications":["Functional dyspepsia","Irritable bowel 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