{"name":"AVROBIO","slug":"avrobio","ticker":"AVRO","exchange":"NASDAQ","domain":"avrobio.com","description":"AVROBIO is a clinical-stage gene therapy company focused on developing treatments for rare genetic diseases. The company's pipeline includes a gene therapy product in phase 2 clinical trials and an enzyme replacement agent. AVROBIO has discontinued its AVR-RD-01 program. The company is positioned to capitalize on the growing gene therapy market.","hq":"Cambridge, MA","founded":0,"employees":"","ceo":"Geoff MacKay","sector":"Clinical-Stage Gene Therapy","stockPrice":0,"stockChange":0,"stockChangePercent":0,"marketCap":"$95M","metrics":{"revenue":0,"revenueGrowth":0,"grossMargin":0,"rdSpend":63489000,"netIncome":-74151000,"cash":253798000,"dividendYield":0,"peRatio":0,"fiscalYear":"FY2026"},"revenueBreakdown":[],"timeline":[{"date":"2026-07-28","label":"Q2 2026 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2026-10-28","label":"Q3 2026 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-01-28","label":"Q4 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-04-28","label":"Q1 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-07-28","label":"Q2 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2027-10-28","label":"Q3 2027 Earnings","type":"earnings","sentiment":"neutral"},{"date":"2025-06-01","label":"AVR-RD-01 patent cliff ($0.0B at risk)","drug":"AVR-RD-01","type":"patent_expiry","sentiment":"negative"}],"diseaseAreas":[{"name":"Other","slug":"other","revenue":0,"percentOfTotal":0,"drugCount":1,"colorKey":"oncology","drugs":[{"name":"Gene therapy","genericName":"Gene therapy","slug":"gene-therapy","indication":"Other","status":"phase_2"}]}],"pipeline":[{"name":"Gene therapy","genericName":"Gene therapy","slug":"gene-therapy","phase":"phase_2","mechanism":"Small molecule","indications":[],"catalyst":""}],"recentEvents":[{"date":"2024-02-27","type":"regulatory","headline":"AVROBIO Announces FDA Clearance of Investigational New Drug (IND) Application for AVR-RD-04","summary":"AVROBIO announced that the FDA has cleared the IND application for AVR-RD-04, a gene therapy product for Fabry disease.","drugName":"AVR-RD-04","sentiment":"positive"},{"date":"2023-11-14","type":"earnings","headline":"AVROBIO Reports Third Quarter 2023 Financial Results","summary":"AVROBIO reported its third quarter 2023 financial results, including revenue and net loss.","drugName":"","sentiment":"neutral"},{"date":"2023-08-16","type":"deal","headline":"AVROBIO Announces Collaboration with the National Institutes of Health (NIH)","summary":"AVROBIO announced a collaboration with the NIH to develop gene therapies for rare genetic diseases.","drugName":"","sentiment":"positive"}],"realNews":[{"date":"2026-02-26","type":"regulatory","source":"SEC EDGAR","summary":"8-K filed with SEC: 8-K","headline":"SEC 8-K: 8-K","sentiment":"neutral"},{"date":"2026-02-26","type":"earnings","source":"SEC EDGAR","summary":"10-K filed with SEC: 10-K","headline":"Annual Report (10-K) Filed","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMikAFBVV95cUxOWGRlMkd3VmQ4ZTNCOVdWanJqMTlxLXJDWmdqMmJQNHFSbXZUbzNJeGhtTEE1QU5HTDFzN0Z3OVY4Qk9qdWJkNk8wTDczMnRoejRvVWZQdXlhc3l2dTVfUFY2cERFWWNIRXRuZ3pqN3hOZmlNMDE5c3hyTUtheF9QbE5qRlRSZUZDS1ZUaWdjaU4?oc=5","date":"2024-01-31","type":"deal","source":"BioPharma Dive","summary":"Avrobio’s road ends in reverse merger with Tim Springer-backed startup - BioPharma Dive","headline":"Avrobio’s road ends in reverse merger with Tim Springer-backed startup","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMinAFBVV95cUxQZm9Ua09xaXNLWG1RcnZ3X0pEY1pUMFRPX1VaMGJ2Q2Zpckxfc19xbHd2dkdiRmRoa3FlbFR3ekxJWDFKVXhWekJrbkhGR2dyMC1ELVRoeUFtNDk0cm9LWklOT0Q3REE2N2xzWDlMeWFNbkRTN2lWQ0lueXc1cmt2Zk1Gcm5GRlUzSC1oaktfVjEzTXNnMXVjbm9TekI?oc=5","date":"2024-01-30","type":"deal","source":"Fierce Biotech","summary":"Avrobio's corporate tremor attracts Tectonic for reverse merger - Fierce Biotech","headline":"Avrobio's corporate tremor attracts Tectonic for reverse merger","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiqAFBVV95cUxPZElkX3VXeXBUNTNyOXJSSms1MVJXOXNBT0VBTzIxVmVuUXc0UmJUV3praklsYUlwcEstOFhGX053cGhZUVRKWGtTZnVidGh6cTk4SDIwYXlLSkNCUHE0d2oyajRfNk5ldFVWX1M0NjVvNm9yWjBQbUVKRnEtd0xRWWJVc0x5NUlMcnFaaGQtYWZydlJmQ2ZVcE5HdkVURl9rY2NhdEZuVmc?oc=5","date":"2024-01-30","type":"deal","source":"Business Wire","summary":"AVROBIO and Tectonic Therapeutic Announce Merger - Business Wire","headline":"AVROBIO and Tectonic Therapeutic Announce Merger","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMikAFBVV95cUxOT2VzMkppd3BhUTU2V2FiQkd1VHZwSl8waEE5RVFTYnZ0VUNIZlVtMEFfUEU4RWFkVzlmSzdRMkdEaEhLQzVzMElkUENUMk01VExKUnBhaDMzV2llbTRUUHNaVzYwQ3VKS2VrcU85aXR1U2ZteGpFUmZzRVdTR1JlRXo0S2k4TmM0NkRWM0p0TXU?oc=5","date":"2024-01-30","type":"pipeline","source":"Contract Pharma","summary":"Avrobio and Tectonic Therapeutic to Merge - Contract Pharma","headline":"Avrobio and Tectonic Therapeutic to Merge","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMikAFBVV95cUxNZE1TTGNKTkhlblVCbUlsUmtPbktBQnZrR3hGSU1GeDRqX2RDZU8wUkw4X3k1T25aZzlPbC16eDg5N1Y1RjYtVmk3NVRFRHFIMlJ4Z2hCVHpYZWt4UFh6U3ZpQVZpcXJ3LXJWZ3FLWi0xUXFZdVdPbEJsTmhaYkYzNlJ1RHZISWpidVRhY3ZhMWM?oc=5","date":"2023-07-12","type":"pipeline","source":"Contract Pharma","summary":"Avrobio to Explore Strategic Alternatives - Contract Pharma","headline":"Avrobio to Explore Strategic Alternatives","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiogFBVV95cUxOZzhSc0pCaldlS0pyLUs3a0ZCVWNFdUdqWnplQ09iNHpwTlhTR2IybWFzSXJmaktuXzR5U3AwYWVBbENqSGsteGVzS0hzbmhWUnNSQkhyX3NCcXk5Q01VaFJHRHRPQWVwSzdqeTFNTmk0YW9KOWJoTnZSM1NqekxkS2lBUllsVWFnQ0ZSRVpGUnV4VHRRQkJXM3FQdHNWel85eVE?oc=5","date":"2023-07-12","type":"pipeline","source":"BioPharma Dive","summary":"Avrobio halts gene therapy research and considers a sale - BioPharma Dive","headline":"Avrobio halts gene therapy research and considers a sale","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMijwFBVV95cUxOS1NyNzBtcEx2WFNCcnQzeTVtTVpFdF9rRHJFVVY2aVN1cjc4amxLQVJ3WVZsaDBPVzNKQzh0SHBucG1EdklEMGFEWUFvbzRVUlRuOTVtV2RCbWh6TDVLc3Zmak4taXJsaXM1THprdHZTY3JQVFFORV9HTHBIcXQ1T19NaU10a0Y0RGotaHprRQ?oc=5","date":"2023-05-30","type":"pipeline","source":"PharmTech.com","summary":"Novartis Purchases Cystinosis Gene Therapy from AVROBIO - PharmTech.com","headline":"Novartis Purchases Cystinosis Gene Therapy from AVROBIO","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMilgFBVV95cUxPS3B3NDM2SndhUmlrNzJBbTlxMlQ4QnRlODJDV3VxNU5wOVFUYVFYeS1OSHJRb1FDN0xYOFdyRmRDREdIblBTMEF2S2x0OC1JMFEwTHZmeno5VVdoRkxwbGhZRVdBMkZ6cERqQ2E5OHVvNFllczRXQU5qY0RNb1I4NFhoNmZuWl9QcllVV0lON1V6b2R5dHc?oc=5","date":"2023-05-26","type":"deal","source":"Labiotech.eu","summary":"Novartis buys AVROBIO cystinosis gene therapy program for $87.5M - Labiotech.eu","headline":"Novartis buys AVROBIO cystinosis gene therapy program for $87.5M","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMigAFBVV95cUxPWHlYUzlTVzBkUjJFVVZTbzk3MFhRdWxwYVZYSmlYdXZHUkRGcjVvbEVZQzVMQXF0alhkTnhsR2dQTHNBalB4TTV2SFZuQlBacGdkQ3NpUy1JeEtFNWkwMHhSZUtuV3EyS1B6QlAyS1kxOWZUalZ0VnNsMFBwRzVEcg?oc=5","date":"2023-05-24","type":"deal","source":"Pharmaceutical Executive","summary":"Novartis Acquires Avrobio’s $88M Gene Therapy - Pharmaceutical Executive","headline":"Novartis Acquires Avrobio’s $88M Gene Therapy","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMisAFBVV95cUxNMkUxbUtMd3ZXUlJLYXU2RDZCOGM4SW9EQ3JmR2F0aGR2QUFlODdUc2hxN1VfUTBlcnRET0VMRzF2UkhJcUhGNFVmZFFrRnE3NFpWdkhfTy1UUkF3VEtXYzhlcDNpRzI4enZrRHhFMllPc1J1WDlFTV96cTJIa2t2UWZPV1M4Um9pRW5feXRzRFhDeHE3b3l6eHFuc0czM3pXYlE3Q0tBRVRwTTROZUVWSw?oc=5","date":"2023-05-23","type":"pipeline","source":"BioProcess International","summary":"Novartis adding cystinosis gene therapy candidate from AvroBio - BioProcess International","headline":"Novartis adding cystinosis gene therapy candidate from AvroBio","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMilwFBVV95cUxQOGo1MkhsY1hoZlJwclVGMzgzcEJOOV9rVVctQUNCZkpLMXdxTFhYeW5yeUNyc0dMYndUb2JHX093UHFrRFZNNVRlbHljYW93T0ZILXgxMjRzSmJoZHZkeHZsd3ltNGstZ1hlajJEclpOOU5jOXlXUWxUWXVTaXpaODNDc0I5S1FBdFJCeG95SHhVS0RWVkIw?oc=5","date":"2021-10-26","type":"pipeline","source":"citybiz","summary":"AVROBIO Appoints Essra Ridha as Chief Medical Officer - citybiz","headline":"AVROBIO Appoints Essra Ridha as Chief Medical Officer","sentiment":"neutral"},{"url":"https://news.google.com/rss/articles/CBMiwAFBVV95cUxPXzZ3NUZxR3lrUWxUNVlsT0pmeXVrdE00T2Rubi1QLURtSjBQX1ZSblVoSTJQZk81V3Zydkt5bEpHbzdzREhwVHlnRmlxcHFpTjBhaEl6Ti04ZEgzVHl4QmtqQy1NSGNlYWhfcW9mcVFTZW5fRVFYMWtnWXlnVzVFRUpOS0VYdXJ4ank3bDlzb25yNE53NTdJa0M5bUlySGhWMGF2bTFCUnd0SjZ3OFhubTNMMnU3Qy13Sjk4SXdaUzk?oc=5","date":"2021-07-26","type":"pipeline","source":"Fierce Pharma","summary":"Robots, automation and pod factories: How cell and gene therapy makers are catching production up to speed - Fierce Pharma","headline":"Robots, automation and pod factories: How cell and gene therapy makers are catching production up to speed","sentiment":"neutral"}],"patents":[{"drugName":"AVR-RD-01","drugSlug":"generic","patentNumber":"","type":"Patent Cliff","expiryDate":"2025-06-01","territory":"US","annualRevenue":0}],"drugCount":1,"phaseCounts":{"phase_2":1},"enrichmentLevel":3,"visitCount":1,"keyCompetitors":["Bluebird Bio","Sangamo Therapeutics","Editas Medicine"],"therapeuticFocus":["Rare Genetic Diseases","Gene Therapy"],"financials":{"source":"sec_edgar","revenue":null,"revenuePeriod":null,"revenueHistory":[],"grossProfit":null,"grossProfitHistory":[],"rdSpend":63489000,"rdSpendHistory":[],"sgaSpend":null,"operatingIncome":null,"operatingIncomeHistory":[],"netIncome":-74151000,"netIncomeHistory":[],"eps":null,"epsHistory":[],"cash":253798000,"cashHistory":[],"totalAssets":261038000,"totalLiabilities":null,"totalDebt":null,"equity":null,"operatingCashflow":null,"operatingCashflowHistory":[],"capex":null,"capexHistory":[],"freeCashflow":null,"dividendsPaid":null,"buybacks":null,"employees":null,"segmentRevenue":[],"geographicRevenue":[],"ciks":null,"lastFiledAt":null},"yahoo":null}